María Luisa Somoza

ORCID: 0000-0002-0141-8914
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About
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Research Areas
  • Allergic Rhinitis and Sensitization
  • Food Allergy and Anaphylaxis Research
  • Contact Dermatitis and Allergies
  • Drug-Induced Adverse Reactions
  • Asthma and respiratory diseases
  • Urticaria and Related Conditions
  • Occupational exposure and asthma
  • Eosinophilic Esophagitis
  • Dermatology and Skin Diseases
  • Mast cells and histamine
  • Pharmaceutical studies and practices
  • Medical Imaging and Pathology Studies
  • Transgenic Plants and Applications
  • Heterotopic Ossification and Related Conditions
  • Pediatric health and respiratory diseases
  • Eosinophilic Disorders and Syndromes
  • Indoor Air Quality and Microbial Exposure
  • Plant Reproductive Biology
  • Inhalation and Respiratory Drug Delivery
  • Soybean genetics and cultivation
  • Plant Surface Properties and Treatments
  • Seed Germination and Physiology
  • Agricultural pest management studies
  • Mediterranean and Iberian flora and fauna
  • Blood disorders and treatments

Hospital Universitario Infanta Leonor
2015-2024

Instituto de Investigación Biomédica de Málaga
2024

Hospital Universitario 12 De Octubre
2004

An increasing number of patients show immediate selective hypersensitivity reactions to clavulanic acid (CLV) and amoxicillin (AX), probably due their increased prescription. The maintenance this response should be established.To assess that the AX or CLV is maintained after repeated administration penicillin G (PG)/penicillin V (PV) AX.Patients with proven (Group A) B) were included. Diagnosis was performed using skin tests major minor determinants PG (PPL/MDM), by drug provocation test...

10.1111/all.12636 article EN Allergy 2015-04-24

<b><i>Background:</i></b> Component-resolved diagnosis reveals the IgE response to many inhaled, food, and other allergens, improving understanding of allergic diseases. <b><i>Objective:</i></b> The aims study are recognition different lipid transfer proteins (LTPs) allergen families in a large group people sensitized Pru p 3 analyze relationship between clinical entities allergens. <b><i>Methods:</i></b> This...

10.1159/000511977 article EN International Archives of Allergy and Immunology 2020-12-18

Peach tree (PT) pollen sensitization is highly prevalent in subjects living areas where this widely cultivated. None of the allergens responsible for these sensitizations have been identified so far. Our aim was to identify most relevant PT and analyze their capacity inducing respiratory symptoms. We studied sixty-two individuals sensitized who developed symptoms after its exposure. The IgE binding profile on peach extract by means immunoblotting using sera from analyzed. Protein...

10.1371/journal.pone.0230010 article EN cc-by PLoS ONE 2020-03-19

Abstract Background Beta‐lactams generate different allergenic determinants that induce selective or cross‐reactive drug hypersensitivity reactions (DHRs). We aimed to identify the drugs involved, selectivity of response, mechanism, and value diagnostic tests for establishing a diagnosis in children evaluated DHRs beta‐lactams. Methods Prospective study evaluating aged under 16 years reporting Reactions were classified as immediate non‐immediate reactions. The workup included sIgE, skin...

10.1111/pai.13608 article EN Pediatric Allergy and Immunology 2021-07-29

Background: Although plant and fruit pollens are entomophilous relevant in exposed workers, we have shown a high frequency of sensitisation symptoms induction peach tree pollen (PTP) Prunus persica 9 (Pru p 9) adults from areas cultivars. Methods: We studied the clinical relevance PTP Pru large group children adolescents aged 3–19 years. A detailed questionnaire plus skin prick testing to prevalent allergens, PTP, were carried out. The was established by nasal provocation test (NPT) symptom...

10.1159/000502352 article EN International Archives of Allergy and Immunology 2019-01-01

Objectives Several studies have described peach tree (PT) as an occupational allergen. The aim of this work was to assess the effect Prunus persica 9 (Pru p 9), a recently identified allergen from PT pollen, in exposed workers. Methods study included people who reported respiratory symptoms after handling orchards during flowering period (Blanca village, Murcia region, south-east Spain). After completing detailed questionnaire, participants underwent skin prick test (SPT) and nasal...

10.1136/oemed-2020-106641 article EN Occupational and Environmental Medicine 2020-10-16

Peach tree allergens are present in fruit, pollen, branches, and leaves, can induce systemic, respiratory, cutaneous, gastrointestinal symptoms. We studied the capacity of peach fruit/Pru p 1, Pru 3, 4, 7 pollen/Pru 9 for inducing symptoms following oral or respiratory exposure a large group subjects. included 716 adults (aged 21 to 83 y.o.) exposed pollen fruit intake study population. Participants completed questionnaire were skin tested with panel inhalant food allergens, including...

10.1371/journal.pone.0255305 article EN cc-by PLoS ONE 2021-08-19

Clavulanate, a beta-lactam associated with amoxicillin, is frequently prescribed in patients at all ages. Recent data implicate amoxicillin-clavulanate up to 80% of allergy cases. We assessed clavulanate's role inducing allergic reactions this combination treatment, focus on selective immediate reactions.Adults (≥ 16 years) reporting history were evaluated through allergological workup, using modified European Academy Allergy and Clinical Immunology guidelines. Patients first underwent skin...

10.4168/aair.2023.15.2.201 article EN Allergy Asthma and Immunology Research 2023-01-01

The prevalence of asthma has increased in recent decades. Among the reasons for this increase is environmental pollution. Pollutants cause bronchial inflammation and introduce modifications pollen, making it more allergenic.Assess symptoms medication requirements asthmatic patients with grass allergies Madrid (high urban pollution) Ciudad Real (low pollution), simultaneously evaluate vitro effects that pollen collected both areas on immune cells patients.During two seasons, from cities were...

10.1111/cea.14041 article EN Clinical & Experimental Allergy 2021-11-06

Allergy can start at early ages, with genetic and environmental factors contributing to its development.The study aimed describe the pattern of sensitisation allergy in children adolescents Spanish versus Moroccan ancestry but born same rural area Spain.Participants were (3-19 years) or descent, Blanca, Murcia (Spain). A detailed questionnaire was completed, skin prick tests performed assess reactions most prevalent pollen allergens (O. europaea, P. pratense, S. kali, C. arizonica,...

10.2147/jaa.s370279 article EN cc-by-nc Journal of Asthma and Allergy 2022-09-01

Food allergy is an increasing health problem with many proteins involved that belong mainly to a limited number of families. They show high level cross-reactivity. In the Mediterranean area, most prevalent food allergens are those vegetal origin. Although tomato (Solanum lycopersium L.) one implicated foods, studies on identification and relevance their have not been carried out in detail. This could be particularly relevant for seeds as happen other fruits like kiwi. The aimed was analyse...

10.1186/2045-7022-5-s3-p120 article EN cc-by Clinical and Translational Allergy 2015-03-30

Exposure to cat allergens is often difficult avoid. Here, we evaluated the safety and effectiveness of a depigmented, polymerized epithelium extract (Dpg-pol-cat) for treatment allergic rhinoconjunctivitis asthma.

10.1159/000541838 article EN International Archives of Allergy and Immunology 2024-11-14
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