Shosaku Kashiwada

ORCID: 0000-0002-0148-2107
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About
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Research Areas
  • Environmental Toxicology and Ecotoxicology
  • Microplastics and Plastic Pollution
  • Nanoparticles: synthesis and applications
  • Mercury impact and mitigation studies
  • Effects and risks of endocrine disrupting chemicals
  • Reproductive biology and impacts on aquatic species
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Pesticide and Herbicide Environmental Studies
  • Toxic Organic Pollutants Impact
  • Aquaculture Nutrition and Growth
  • Fish Ecology and Management Studies
  • Heavy Metal Exposure and Toxicity
  • Aquaculture disease management and microbiota
  • Pesticide Exposure and Toxicity
  • Recycling and Waste Management Techniques
  • Graphene and Nanomaterials Applications
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Isotope Analysis in Ecology
  • Geochemistry and Elemental Analysis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Angiogenesis and VEGF in Cancer
  • biodegradable polymer synthesis and properties
  • Air Quality and Health Impacts
  • Chromium effects and bioremediation
  • Anesthesia and Neurotoxicity Research

Toyo University
2015-2024

Nippon Shokubai (Japan)
2021

Centre for Life
2014-2020

Bunkyo University
2018

University of South Carolina
2008-2012

National Institute for Environmental Studies
2005-2009

Duke University
2002-2007

Shimane University
1995-2002

Fujieda Municipal General Hospital
1998

Because the environmental fate of manufactured nanoparticles is considered an emerging concern, I used water-suspended fluorescent (solid latex solution) to investigate distribution in eggs and bodies see-through medaka (Oryzias latipes).Particles 39.4-42,000 nm diameter were adsorbed chorion accumulated oil droplets; 474-nm particles had highest bioavailability eggs. Particles 39.4 shifted into yolk gallbladder during embryonic development. Adult 39.4-nm mainly gills intestine when exposed...

10.1289/ehp.9209 article EN public-domain Environmental Health Perspectives 2006-07-05

Mature male medaka were continuously exposed to 0.005, 0.0–5 or 1.0 ppb of estradiol-17β (E2 0.1, 10 100 p-nonylphenol (NP) bis-phenol-A (BPA). Female-specific proteins (Fsp) induced in 0.005 E2, 0.1 NP, BPA. Concentrations pbb E2 and NP corresponded concentrations these chemicals detected river water Japan. The abilities the 3 induce Fsp E2> NP> Embryonic BPA under conditions static-renewal for 200–230 days until pre-maturity. Survival ratios declined more than 25 50 ppb,...

10.2166/wst.2001.0079 article EN Water Science & Technology 2001-01-01

We evaluated if the choice of no observed effect concentration (NOEC) or a 10% (EC10) affects hazardous concentrations for 5% species (HC5s) estimated from sensitivity distributions (SSDs). By reviewing available literature reporting NOECs and reanalyzing original toxicity data to estimate EC10s, we developed two SSDs five chemicals (zinc, lead, nonylphenol, 3,4-dichlorobenzenamine, lindane) based separately on 9–19 EC10s NOECs. On average, point estimates HC5s were 1.2 (range 0.6–1.9) times...

10.1021/acs.est.5b02069 article EN Environmental Science & Technology 2015-07-13

Silver nanomaterials are the major components of healthcare products largely because their antimicrobial effects. However, unintended toxicity to biological organisms and its mechanism not well understood. Using medaka fish embryo model, toxic effects corresponding mechanisms silver nanocolloids (SNC, particle size 3.8 ± 1.0-diameter nm) were investigated. SNC caused morphological changes in embryos including cardiovascular malformations, ischemia, underdeveloped central nervous system eyes,...

10.1021/es2045647 article EN Environmental Science & Technology 2012-05-09

This work reports the distribution of negatively charged, gold core nanoparticles in a model marine estuary as function time. A single dose purified polystyrene sulfonate (PSS)-coated nanorods was added to series three replicate estuarine mesocosms emulate an abrupt nanoparticle release event tidal creek Spartina -dominated estuary. The contained several phases that were monitored: seawater, natural sediments, mature cordgrass, juvenile northern quahog clam, mud snails, and grass shrimp....

10.1021/es402880u article EN Environmental Science & Technology 2013-10-21

The aim of this study is to develop a new methodology based on optical sensors able recognize and characterize microplastics collected in the marine environment. In recent years, pollution represents an environmental emergency with serious effects human health organisms. was carried out different geographical areas. Through hyperspectral imaging (HSI) approach, performed SWIR range (1000-2500 nm), classification model chemometric techniques implemented order identify rapid, non invasive...

10.1117/12.2542793 article EN 2019-11-12

In aquatic environments, silver nanotoxicity depends on salinity.

10.1039/c4en00175c article EN Environmental Science Nano 2014-11-24

Tantalum (Ta) is a technology-critical element (TCE) that growing in global demand because of its use electronic and medical devices, capacitors, aircraft, hybrid cars. Despite economic relevance, little known about environmental concentrations the trophodynamics Ta aquatic food webs have not been studied. Invertebrates fishes from coastal marine representing different climatic zones northwestern Chile, western Chilean Patagonia, Antarctic Peninsula were sampled analyzed for Ta. The trophic...

10.1021/acs.estlett.8b00051 article EN Environmental Science & Technology Letters 2018-03-09

Treatment modalities for kidney disease caused by long-term exposure to heavy metals, such as cadmium (Cd), are limited. Often, chronic, environmental metal is not recognized in the early stages; therefore, chelation therapy an effective option. Extracellular vesicles (EVs) derived from stem cells have been demonstrated reduce pathology both acute and chronic models. To test ability of EVs human bone marrow mesenchymal (hBM-MSCs) treat Cd damage, we generated a Cd-exposed medaka model. This...

10.14814/phy2.14172 article EN cc-by Physiological Reports 2019-07-01

The Japanese archipelago is surrounded by the Sea of Japan, Okhotsk, Pacific Ocean, and East China Sea. oceans are known to be contaminated waste artifacts (marine litter). To investigate how these contaminate sandy beaches in Japan their fate oceans, we sampled sand from 19 ranging western area main island (Honshu), which faces westernmost (Yonaguni Island), Almost all were marine litter. maximum density number pieces was 604,600 per m3 a 2-cm depth on Yonaguni Island. Polystyrene foam most...

10.1007/s44289-024-00029-2 article EN cc-by-nc-nd Deleted Journal 2024-10-10
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