Naila Safdar

ORCID: 0000-0002-0183-9452
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About
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Research Areas
  • Plant tissue culture and regeneration
  • Transgenic Plants and Applications
  • Essential Oils and Antimicrobial Activity
  • Nanoparticles: synthesis and applications
  • Natural Antidiabetic Agents Studies
  • Medicinal Plants and Neuroprotection
  • Phytochemicals and Antioxidant Activities
  • Ethnobotanical and Medicinal Plants Studies
  • Electrochemical sensors and biosensors
  • Advanced Nanomaterials in Catalysis
  • Food Science and Nutritional Studies
  • Tea Polyphenols and Effects
  • Advanced biosensing and bioanalysis techniques
  • CRISPR and Genetic Engineering
  • Proteoglycans and glycosaminoglycans research
  • Plant-Microbe Interactions and Immunity
  • Glycosylation and Glycoproteins Research
  • Plant Genetic and Mutation Studies
  • Phytochemistry and Biological Activities
  • Allelopathy and phytotoxic interactions
  • Natural product bioactivities and synthesis
  • Plant Micronutrient Interactions and Effects
  • Air Quality and Health Impacts
  • Cholinesterase and Neurodegenerative Diseases
  • Genetically Modified Organisms Research

Fatima Jinnah Women University
2016-2024

Quaid-i-Azam University
2008-2013

The present study examined the biological potential and phytochemicals of Sophora mollis, Mucuna pruriens, Indigofera atropurpurea methanolic leaf extracts. In vitro anti-acetylcholinesterase anti-lipase assays were performed using different concentrations plant extracts, IC50 values determined. cytotoxic selected extracts was assessed against HeLa, PC3, 3T3 cell lines an MTT assay. S. mollis extract displayed highest inhibition percentage (114.60% ± 19.95 at 1000 μg/mL) for activity with a...

10.1016/j.heliyon.2023.e15909 article EN cc-by-nc-nd Heliyon 2023-05-01

In allelopathy, one plant suppresses the growth and development of other plant/plants by negatively affecting a variety physiological biochemical reactions. We checked effects methanolic extracts (allelochemical extracts) Phytolacca latbenia (Moq.) H. Walter on antioxidant enzyme activities such as peroxidases (PODs), super oxide dismutases (SODs) catalase (CAT) total protein contents (TPC), cellular injury (CI), malondialdehyde (MDA) in germinating seeds Brassica napus L. (dicot) Triticum...

10.1177/0748233713483205 article EN Toxicology and Industrial Health 2013-04-09

The Fabaceae is renowned for its diverse range of chemical compounds with significant biological activities, making it a valuable subject pharmacological studies. composition and activities three species were investigated using methanol separately in combination dimethyl sulfoxide (DMSO) glycerol extraction. results revealed the highest phenolic (49.59 ± 0.38 mg gallic acid equivalent/g), flavonoid (29.16 0.39 rutin alkaloid (14.23 0.54 atropine equivalent/g) contents Caesalpinia decapetala...

10.1016/j.heliyon.2024.e33668 article EN cc-by-nc-nd Heliyon 2024-06-27

Weeds in Gwalior and nearby regions their medicinal properties: A case studySapna Kondalkar, Avinash Vijay Kumar, Anupam K Mangal, Om Prakash

10.7324/jabb.2016.40306 article EN Journal of Applied Biology & Biotechnology 2016-01-01

Extracellular thermophilic multicopper oxidase i.e. laccase was purified, identified and characterized from Geobacillus stearothermophilus MB600. Fast protein liquid chromatography (FPLC) of lacasse showed a prominent peak at 610 nm. Sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) for presented molecular weight 59.13 kDa. Analysis via Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) confirmed the presence similar to in thermoleovorans B23 sp....

10.1080/16583655.2023.2268903 article EN cc-by Journal of Taibah University for Science 2023-10-26

Abstract Tomato cv Rio Grande plants were transformed with yeast halotolerance genes ( HAL I or II ) using pPM7 pJRM16 , p35 GUSINT as control. Transformation efficiency varied in the three constructs, highest transformation found p35GUSINT. Final selection of transgenic was made on basis PCR. Transgene integration and copy number assessed by Southern hybridisation. The primary transformants allowed to self‐pollinate expected Mendelian ratios studied second‐generation progeny. Five...

10.1111/j.1438-8677.2010.00412.x article EN Plant Biology 2010-11-19

Conventional cancer treatments normally involve chemotherapy or a combination of radio- and chemotherapy. However, the adverse effects synthetic medicines encouraged exploration novel therapeutic medications bio-friendly nature. In an effort to explore anticancer compounds from natural resources, crude extract Peganum harmala (seeds) was fractionated on basis polarity, fractions were further tested for activity. Brine shrimp lethality assays potato disc antitumor used test each fraction...

10.3390/separations9110355 article EN cc-by Separations 2022-11-07

Wide spectrum medicinal significance augments plant utilization as the primary source of significant pharmaceutical agents. In vitro investigation antioxidant and antimicrobial activity highlights therapeutic potential Otostegia limbata. Methanol extract (MEP) shows considerable dose dependent ability at six concentrations (7.81 µg/mL to 250 µg/mL) in 2.2-diphenyl-1-picrylhydrazyl (DPPH) assay, phosphomolybdate assay (PMA) reducing power (RPA). The capability scavenge free radicals mixture...

10.3390/plants10112360 article EN cc-by Plants 2021-11-02
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