A5036179266- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Gastroesophageal reflux and treatments
- Obstructive Sleep Apnea Research
- Allergic Rhinitis and Sensitization
- Ocular Disorders and Treatments
- Voice and Speech Disorders
- Nerve injury and regeneration
- Salivary Gland Disorders and Functions
- Lysosomal Storage Disorders Research
- Glaucoma and retinal disorders
- Contact Dermatitis and Allergies
- Trigeminal Neuralgia and Treatments
- Corneal surgery and disorders
- Biochemical Analysis and Sensing Techniques
- Retinal and Macular Surgery
- Respiratory and Cough-Related Research
- Ophthalmology and Eye Disorders
- Biomedical Research and Pathophysiology
- Hematopoietic Stem Cell Transplantation
- Facial Nerve Paralysis Treatment and Research
- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
Policlinico Umberto I
2021-2022
Sapienza University of Rome
2014-2022
Background: patients with laryngopharyngeal reflux (LPR) showed detectable levels of tear pepsin that explain the nasolacrimal obstruction. The purpose this study was to determine whether LPR show ocular surface changes and investigate relationship between lacrimal concentration alterations. Methods: Fifty positive endoscopic signs for an equal or higher score 13 7 Reflux Symptom Index Finding Score were enrolled. Twenty healthy no disease dry eye included as control group. After evaluation...
Objective Usher’s syndrome type II (USH2) is characterized by moderate to profound congenital hearing loss, later onset of retinitis pigmentosa, and normal vestibular function. Recently, a study investigating the function USH2 patients demonstrated pathologic response tests. In this cross‐sectional we performed tests group with genetic diagnosis demonstrate if damage present in patients. Study Design Cross‐sectional study. Setting Tertiary referral center. Subjects Methods Mutated genes 7...
Abstract This study sought to evaluate the prospective role exerted by vascular endothelial growth factor (VEGF) in modulation of nerve (NGF) and brain‐derived neurotrophic (BDNF) signalling pathways rabbit retina. To reach this aim, anti‐VEGF agents aflibercept ranibizumab were used as a pharmacological approach putative consequences elicited VEGF inhibition on neurotrophin signalling. determined marked imbalance proneurotrophin expression, significant reduction TrkA TrkB phosphorylation...
Fabry disease (FD) is a rare X-linked, lysosomal storage disorder caused by mutations in the alpha-galactosidase gene and characterized neurological, cutaneous, renal, cardiovascular, cochleo-vestibular ocular manifestations. The aim of this study to characterize morphological, functional autophagy-lysosome pathway alterations surface FD patients.Eleven subjects with diagnosis fifteen healthy control were examined. All patients underwent slit lamp examination, corneal aesthesiometry vivo...
To report the case of persistent corneal epithelial defect in total limbal stem cell deficiency (LSCD) after severe firework-related ocular burn treated with autologous Platelet-Rich Plasma (PRP).A young patient, victim fireworks trauma, presented a large affecting central cornea his left eye and progressing to stromal melting, context grade VI surface 12 h involvement. Impression cytology confirmed complete LSCD. Assessment sensitivity by Cochet Bonnet esthesiometer revealed anesthesia....
Obstructive sleep apnoea (OSA) and laryngopharyngeal reflux disease (LPR) are two common diseases that lower patients' quality of life. OSA is defined by cyclic events airflow obstruction occur during sleep, while LPR characterized upper airway inflammatory signs symptoms due to the return gastroduodenal gaseous liquid elements. pH-metry gold standard in diagnosis, but considering its invasiveness among other negative traits, questionnaires catalog such as Reflux Symptoms Index (RSI) Finding...