Chao Chen

ORCID: 0000-0002-0413-2604
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Research Areas
  • Advanced Polymer Synthesis and Characterization
  • Nanoparticle-Based Drug Delivery
  • Polymer Surface Interaction Studies
  • RNA Interference and Gene Delivery
  • biodegradable polymer synthesis and properties
  • Carbon dioxide utilization in catalysis
  • X-ray Diffraction in Crystallography
  • Electrospun Nanofibers in Biomedical Applications
  • Dendrimers and Hyperbranched Polymers
  • Thermal properties of materials
  • Advanced biosensing and bioanalysis techniques
  • Crystallization and Solubility Studies
  • Polymer crystallization and properties
  • Synthesis and properties of polymers
  • Circular RNAs in diseases
  • Silicone and Siloxane Chemistry
  • Thermal Radiation and Cooling Technologies
  • TiO2 Photocatalysis and Solar Cells
  • Catalysis and Oxidation Reactions
  • Pickering emulsions and particle stabilization
  • Trace Elements in Health
  • Biosensors and Analytical Detection
  • Supramolecular Self-Assembly in Materials
  • Asymmetric Hydrogenation and Catalysis
  • Iron Metabolism and Disorders

East China Normal University
2024-2025

University of South China
2022

King Abdullah University of Science and Technology
2021

Beijing University of Chemical Technology
2017-2020

Beijing Advanced Sciences and Innovation Center
2018-2020

Hebei GEO University
2019

Materials Science & Engineering
2017-2018

Beijing University of Civil Engineering and Architecture
2017

Beijing University of Technology
2017

State Key Laboratory of Building Safety and Built Environment
2017

Abstract Over the last few decades, excess exploitation of our planet and degradation environment have gone up at an alarming rate. Environmental problems, especially air water pollution, which takes a huge number years to recover, become major concern affecting progress human society. The overwhelming threats driven global research innovation in development advanced technology devices toward cleaner environment. In this context, generation functional one-dimensional (1-D) nanomaterials has...

10.1515/ntrev-2015-0065 article EN Nanotechnology Reviews 2016-01-01

Abstract Deferoxamine (DFO) is an FDA‐approved naturally occurring iron chelator commonly used to treat transfusion‐induced overload. The abundant and flexible hydroxamic acid groups in DFO enable exceptional binding capacity high protein via hydrogen bonding interactions. However, the applications of sequester intracellular deliver proteins inside cells are limited due poor membrane‐permeability. Herein, fabrication a dynamic polymer proposed achieve robust delivery efficient mitochondrial...

10.1002/smll.202412093 article EN Small 2025-02-13

Peptide-polymer conjugates represent a promising class of compounds that can be used to overcome some the limitations associated with peptides intended for therapeutic and diagnostic applications. The efficient generation well-defined peptide/protein-polymer promote development design synthesis functional drugs gene delivery platforms. In this research, sequence defined cell penetrating peptide (i.e., Transportan 10 (TP 10))-based chain transfer agent (TP-CTA) was designed synthesized in an...

10.1021/acsmacrolett.9b00647 article EN ACS Macro Letters 2020-02-04

The ring-opening copolymerization of epoxides with isothiocyanates (ITCs) is explored for the first time. In presence phosphazenium benzoxide, investigated in this work including propylene oxide, ethylene and cyclohexene oxide were successfully copolymerized both an aromatic ITC, phenyl isothiocyanate, two aliphatic ITCs, ethyl isothiocyanate hexyl isothiocyanate. Effects phosphazene bases used, temperature, Lewis acids, triethyl borane diethyl zinc (ZnEt2), on alternating respectively....

10.1021/acs.macromol.1c01460 article EN Macromolecules 2021-10-08

An ultrasensitive metal-labeled amperometric immunoassay (MLAI) method of proteins is reported, on the basis multiple cycles gold label/silver staining and galvanic replacement reactions (GRRs), followed by simultaneous chemical dissolution/cathodic preconcentration silver for in situ microliter-droplet anodic stripping voltammetry (ASV) detection immunoelectrode. Briefly, antibody 1 (Ab1), bovine serum albumin (BSA), antigen, Au nanoparticles functionalized with 2 (Ab2–AuNPs) were...

10.1021/acs.jpcc.5b12004 article EN The Journal of Physical Chemistry C 2016-02-03

A “grafting from” approach for facile access of multifunctional miktoarm star polymers containing peptide arms.

10.1039/c8py01355a article EN Polymer Chemistry 2018-11-20

These functional peptide-based RAFT agents provide researchers a straightforward access to complex bioconjugates for biomedical applications.

10.1039/c7cc05316a article EN Chemical Communications 2017-01-01

The present study provides a robust method for the preparation of RGD peptide-based polymers that has important implications in synthesized biomaterials support cell adhesion.

10.1039/c7py01887h article EN Polymer Chemistry 2018-01-01

Abstract Addressing the concern of heat accumulation in electronic devices, considerable research efforts have been dedicated to develop composites that are thermally conductive yet electrically insulative. Incorporating hexagonal boron nitride (h‐BN) as fillers shows promise enhancing thermal conductivity polymer composites. However, notable challenges arise from difficulties achieving well dispersion and establishing efficient three‐dimensional networks. This work demonstrated an...

10.1002/pc.27980 article EN Polymer Composites 2023-12-02

Abstract The photodegradation of doxorubicin (Dox) in the presence hydroxypropyl‐ β ‐cyclodextrin (HP‐ ‐CD) was studied; degradation rate constant HP‐ ‐CD estimated by Lineweaver‐Burk analysis approximately three times lower than that free Dox aqueous solution, which shows can enhance photostability solution. enhancement may be attributed to inclusion interaction between and doxorubicin. characterization FTIR, DSC, XRD fluorescence titration indicates 1:1 complex is formed

10.1002/cjoc.201090223 article EN Chinese Journal of Chemistry 2010-07-01

ABSTRACT Ethylene–propylene–diene rubber (EPDM)/clay nanocomposites with crosslinking bonding at the interface were fabricated through intercalation method involving double‐bond functional groups. For comparison, an organoclay modified agent without double bonds was also prepared. X‐ray diffraction indicated that EPDM intercalated into galleries of nanoclay due to organic reagent containing bonds. According dielectric relaxation spectra, segmental greatly confined, strong filler/polymer...

10.1002/app.45553 article EN Journal of Applied Polymer Science 2017-08-31

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in liver cancer, with a high rate metastasis and recurrence. Circular RNA_0061395 (circ_0061395) has been shown to be involved advance HCC. However, interaction between circ_0061395 microRNA (miRNA) HCC not studied. Quantitative real-time polymerase-chain reaction (qRT-PCR) was used detect expression related genes cancer tissues cells. The stability verified by RNase R digestion. Through detection cell behavior...

10.1080/15384101.2022.2092177 article EN other-oa Cell Cycle 2022-07-01

Modification with benzenesulphonate on a phase-transition polymer can improve the protein delivery efficacy, reduce cytotoxicity and adsorption.

10.1039/d4bm01440e article EN Biomaterials Science 2024-01-01

Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Chao Chen, Paul A. Charpentier; The effect of TiO2 nanostructures on self-degrading polyurethane foams. AIP Conf. Proc. 31 March 2014; 1590 (1): 251–258. https://doi.org/10.1063/1.4870226 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar...

10.1063/1.4870226 article EN AIP conference proceedings 2014-01-01

The floating screed hot water floor (FSHWF) has been used widely in the residential buildings due to its thermal comfort. delay and attenuation of floor's surface temperature are related structure、material、indoor temperature、initial heating's value. Thus, by analyzing these influence factors getting best adjusting way, FSHWF can be obtained meet requirements users. Therefore, this paper, regulation modes heating is studied, impacts multiple on floors' process analyzed calculation model,...

10.1016/j.proeng.2017.10.077 article EN Procedia Engineering 2017-01-01
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