- Cervical Cancer and HPV Research
- Women's cancer prevention and management
- Global Cancer Incidence and Screening
- Endometrial and Cervical Cancer Treatments
- Colorectal and Anal Carcinomas
- Science and Education Research
- Glioma Diagnosis and Treatment
- Psychology and Mental Health
- Central Venous Catheters and Hemodialysis
- Chemotherapy-related skin toxicity
- Nail Diseases and Treatments
- BRCA gene mutations in cancer
- Nutrition and Health in Aging
- Brain Metastases and Treatment
- Youth, Drugs, and Violence
- Cancer Risks and Factors
- Cancer survivorship and care
- Environmental Sustainability and Education
- Myasthenia Gravis and Thymoma
- Healthcare cost, quality, practices
- Childhood Cancer Survivors' Quality of Life
- Social and Political Issues
- Vascular Malformations and Hemangiomas
- Maternal and Neonatal Healthcare
- Body Contouring and Surgery
Instituto de Medicina Integral Professor Fernando Figueira
2016-2024
AC Camargo Hospital
2010-2011
This phase II clinical trial evaluated the safety and antitumor activity of balstilimab, an anti-PD-1 antibody, in patients with previously-treated, recurrent/metastatic cervical cancer.Eligible were 18 years or older recurrent and/or metastatic cancer who had relapsed after a prior platinum-based treatment regimen for advanced disease. Balstilimab was administered intravenously at 3 mg/kg once every two weeks, up to 24 months. The primary endpoint objective response rate (ORR, RECIST v1.1)...
Docetaxel is a new taxoid antineoplastic drug widely used for advanced breast cancer. Skin and nail toxicity are one of the more frequent nonhematologic adverse reactions. Besides dark pigmentations Beau’s lines, subungual hemorrhage, orange discoloration, acute painful paronychia, onycholysis, hyperkeratosis transverse loss plate described. The type alteration related with number cycles administered there no efficacious preventive measures to avoid its development. Clinicians should...
Coronavirus disease 2019 (COVID-19) and cancer are serious public health problems worldwide. However, little is known about the risk factors of in-hospital mortality among COVID-19 patients with without in Brazil. The objective this study was to evaluate compare according gender topography during year 2020 Brazil.This a secondary data hospitalized adult diagnosis by real-time polymerase chain reaction testing were collected from Influenza Epidemiological Surveillance Information System.This...
Objective To evaluate the performance of 18F-fluorodeoxyglucose positron emission tomography ( 18 F-FDG PET/CT) radiomic features to predict overall survival (OS) in patients with locally advanced uterine cervical carcinoma. Methods Longitudinal and retrospective study that evaluated 50 epidermoid carcinoma (clinical stage IB2 IVA according FIGO). Segmentation 18F-FDG PET/CT tumors was performed using LIFEx software, generating features. We used Mann–Whitney test select associated clinical...
Cervical cancer is the fourth most common in women worldwide. Epidemiological and quality of life (QoL) data patients with cervical from low- middle-income countries are scarce. We aimed to describe sociodemographic clinicopathological characteristics at diagnosis Brazil.EVITA a prospective cohort study newly diagnosed May 2016 December 2017, stages I-IVB, 16 Brazilian sites representing five regions. At baseline, medical evaluation was performed European Organization for Research Treatment...
CONTEXT: Non-small cell lung cancer (NSCLC) progresses to distant metastases in most cases. The frequent sites for are the bones, central nervous system, adrenal glands and liver. Dissemination skin, myocardium, thyroid gland intestine may occur, but is rare. CASE REPORT: We describe a case of squamous carcinoma lungs, with colon thyroid, 66-year-old female patient. lesion was unresectable chemotherapy started. patient evolved intestinal subocclusion, colonoscopy showed presence polyp....
Introdução: O câncer de colo útero (CCU) apresenta alta prevalência e
<h3>Introduction/Background</h3> In Brazil, excluding non-melanoma skin tumours, cervical cancer is the third most common among women. 2022, 16,710 new cases were estimated, which represents 15.38 cases/100,000 regional analysis, second in Northeast (16.10/100,000). Socio-economic factors are closely related to prevalence and incidence of this worldwide. This study sought map profile patients affected by disease between 2016–2021 reference services Pernambuco. <h3>Methodology</h3> was a...
<h3>Introduction/Background</h3> Cervical cancer has a high lethality rate in our state due to the lack of adequate access and knowledge about cancer. In turn, it slow evolution great potential for prevention cure. The most accessible early detection method Brazil is Pap smear and, despite existence numerous public policies encourage screening, there considerable importance diagnosis. aim this study was assess main obstacles cervical screening. <h3>Methodology</h3> Descriptive,...
e17510 Background: Cervical cancer (CC) is the fourth most common malignancy in women worldwide and around 85% of cases are currently diagnosed underdeveloped countries. Effective screening with Pap smear HPV test can reduce incidence CC about 90%. In Brazil, few retrospective/cancer registry studies have described patterns previous to diagnosis. We aim assess rates major study Brazil (EVITA). Methods: Prospective, observational study, within 16 sites representing five Brazilian regions....
e17509 Background: Cervical cancer (CC) is the fourth most common malignancy in women worldwide and third Brazil. It a health problem low middle-income countries (LMIC), where screening programs have failed to achieve its potential 85% of global disease burden is. Therefore, studies aiming describe population patients those are uttermost importance for planning public policies. EVITA major prospective CC cohort study performed Here we present patients’ baseline characteristics diagnostics...
Objetivo: No Brasil, dados clínicos e custos econômicos do câncer de pulmão não pequenas células (CPNPC) são escassos. Portanto, conduzimos este estudo para coletar mundo real sobre padrões tratamento uso recursos CPNPC avançado (CPNPCa) em pacientes instituições privadas brasileiras. Métodos: Coletamos prontuários seis no Brasil. Os elegíveis tinham diagnóstico ou recorrente (estágios IIIB IV) entre janeiro 2011 julho 2014, haviam recebido pelo menos duas linhas quimioterapia. Dados foram...
Objective:To determine risk factors for early death identified the Comprehensive Geriatric Assessment (CGA) in elderly patients with gynecological cancer (EPGC) Methods:Prospective cohort study.Participants a recent diagnosis of were from eight community hospitals and one center Northeast Brazil recruited during their first medical appointment at outpatient oncologic clinic.A basal CGA was done before treatment decision (ADL, Charlson Comorbidity Index-CCI, Karnofsky Performance status -KPS,...
OBJECTIVE: We report the results of a panel Brazilian experts and provide recommendations for management these patients. MATERIAL AND METHODS: The convened composed by 28 local opinion leaders, addressed 59 multiple-choice questions taking into account published scientific literature their own clinical experience. level agreement among members was qualified as (1) consensus, when at least 75% voting members; (2) majority vote (50%-74.9%); or (3) less than vote. RESULTS: There eight 10 on...