Alexei Zverovitch

ORCID: 0000-0002-0567-5440
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • Lung Cancer Diagnosis and Treatment
  • Radiation Dose and Imaging
  • Advances in Oncology and Radiotherapy
  • Radiation Effects in Electronics
  • Radiation Therapy and Dosimetry
  • Radiation Detection and Scintillator Technologies

Google (United States)
2021-2024

Google (United Kingdom)
2020-2021

Over half a million individuals are diagnosed with head and neck cancer each year globally. Radiotherapy is an important curative treatment for this disease, but it requires manual time to delineate radiosensitive organs at risk. This planning process can delay while also introducing interoperator variability, resulting in downstream radiation dose differences. Although auto-segmentation algorithms offer potentially time-saving solution, the challenges defining, quantifying, achieving expert...

10.2196/26151 article EN cc-by Journal of Medical Internet Research 2021-07-12

Over half a million individuals are diagnosed with head and neck cancer each year worldwide. Radiotherapy is an important curative treatment for this disease, but it requires manual time consuming delineation of radio-sensitive organs at risk (OARs). This planning process can delay treatment, while also introducing inter-operator variability resulting downstream radiation dose differences. While auto-segmentation algorithms offer potentially time-saving solution, the challenges in defining,...

10.48550/arxiv.1809.04430 preprint EN other-oa arXiv (Cornell University) 2018-01-01

Organ-at-risk segmentation for head and neck cancer radiation therapy is a complex time-consuming process (requiring up to 42 individual structure, may delay start of treatment or even limit access function-preserving care. Feasibility using deep learning (DL) based autosegmentation model reduce contouring time without compromising contour accuracy assessed through blinded randomized trial oncologists (ROs) retrospective, de-identified patient data.

10.3389/fonc.2023.1137803 article EN cc-by Frontiers in Oncology 2023-04-06

This study aims to address the limitations of traditional methods for calculating linear energy transfer (LET), a critical component in assessing relative biological effectiveness (RBE). Currently, Monte Carlo (MC) simulation, gold-standard accuracy, is resource-intensive and slow dose optimization, while speedier analytical approximation has compromised accuracy. Our objective was prototype deep-learning-based model dose-averaged LET (LET

10.1088/1361-6560/ad4844 article EN cc-by Physics in Medicine and Biology 2024-05-07

Abstract This document reports the design of a retrospective study to validate clinical acceptability deep-learning-based model for autosegmentation organs-at-risk (OARs) use in radiotherapy treatment planning head & neck (H&N) cancer patients.

10.1101/2021.12.07.21266421 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2021-12-08

<sec> <title>BACKGROUND</title> Over half a million individuals are diagnosed with head and neck cancer each year globally. Radiotherapy is an important curative treatment for this disease, but it requires manual time to delineate radiosensitive organs at risk. This planning process can delay while also introducing interoperator variability, resulting in downstream radiation dose differences. Although auto-segmentation algorithms offer potentially time-saving solution, the challenges...

10.2196/preprints.26151 preprint EN 2020-11-30
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