A5003529311- Gut microbiota and health
- Natural Antidiabetic Agents Studies
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Clostridium difficile and Clostridium perfringens research
- Dermatology and Skin Diseases
- Animal Behavior and Welfare Studies
- Probiotics and Fermented Foods
- Food Security and Socioeconomic Dynamics
- Peptidase Inhibition and Analysis
- Infant Nutrition and Health
- Food and Agricultural Sciences
- Bee Products Chemical Analysis
- Immune Cell Function and Interaction
- Metabolism, Diabetes, and Cancer
- Animal health and immunology
- Biochemical Analysis and Sensing Techniques
- Neuropeptides and Animal Physiology
- Phytochemicals and Antioxidant Activities
- Gastrointestinal motility and disorders
- Polysaccharides Composition and Applications
- Traditional and Medicinal Uses of Annonaceae
- Protein Kinase Regulation and GTPase Signaling
- Digestive system and related health
- Animal Genetics and Reproduction
University of Veterinary Medicine Vienna
2021-2024
California Institute of Technology
1990
Cinnamomum cassia (Family: Lauraceae) is an Ayurvedic medicinal plant used traditionally for the treatment of a number diseases, including diabetes. The hypoglycemic effect this has been established in vivo. However, effects cinnamic acid, isolated from C. cassia, on insulin signaling cascade vitro model have not elucidated. Hence, aim present study was to evaluate anti-diabetic acid glucose transport by L6 myotubes.The mechanism action determined using specific targets pathway, protein...
The mechanism of action Annona squamosa hexane extract in mediating antihyperglycemic and antitriglyceridimic effect were investigated this study.
Postnatally, short-chain fatty acids (SCFA) are important energetic and signaling agents, being involved in host nutrition, gut imprinting immune barrier function. Whether SCFA exert similar effects during the late fetal phase has been insufficiently elucidated. This study aimed to evaluate whether jejunum senses modify muscle tension epithelial permeability related jejunal tissue from porcine fetus gestation. Exposure of a mix (70 µmol/mL) an organ bath for 20 min lowered tension. Moreover,...
Dietary and microbially derived fatty acids (FA) play important roles in gut mucosal inflammatory signaling, barrier function, oxidative stress response. Nevertheless, little information is available about gastrointestinal FA profiles receptor distribution pigs, especially for long-chain (LCFA). Therefore, the present pilot study aimed to (1) investigate profiles; (2) link luminal expression of genes related sensing signaling; (3) assess potential dietary effects on systemic lipid metabolism...
Despite their anti-inflammatory properties, role in barrier function, absorption and microbial balance the gut, knowledge on maturational dietary effects intestinal short-chain fatty acids (SCFA) neonatal piglets is scarce. Moreover, little information exists whether SCFA lactic acid (LA) modulates gut motility at this age. The present study aimed (1) to investigate changes profile with without creep feeding of first 3 wk life; (2) examine LA muscle contractibility jejunal tissue from ex...
Little information is available on age- and creep-feeding-related microbial immune development in neonatal piglets. Therefore, we explored gut-site-specific alterations the microbiome, metabolites, histo-morphology, expression of genes for signaling, as well barrier function suckling newly weaned piglets that were receiving sow milk only or additionally offered creep feed from day life (DoL) 10. The experiment was conducted two replicate batches. Creep intake estimated at litter level....
Abstract Information about the full spectrum of metabolites present in porcine colostrum and factors that influence metabolite abundances is still incomplete. Parity number appears to modulate concentration single colostrum. This study aimed 1) characterize metabolome composition 2) assess effect parity on profiles Sows (n = 20) were divided into three groups: A) sows 1 2 8), B) 3 4 6), C) 5 6 6). Colostrum was collected within 12 h after parturition. A total 125 identified using targeted...
The re-integration of former foodstuffs, such as bakery products (BP), into pig feed reduces the feed-food competition and increases sustainability production. Nevertheless, there are concerns about altered fatty acid profile in BP compared to standard diets their effects on meat quality intestinal microbiome. present study investigated replacing 30% cereal grains with diet performance, microbiome composition metabolites feces fattening pigs, economic aspects characteristics. A total 132...
Weaning often leaves the piglet vulnerable to gut dysfunction. Little is known about acute response of a mucosa primed by milk-oriented microbiome before weaning plant-oriented (POM) after weaning. We evaluated epithelial structure, secretory and permeability in small large intestines piglets receiving milk-based (i.e., preweaning) or plant-based diet postweaning) POM inocula using intestinal loop perfusion assays (ILPA). The were prepared from jejunal colonic digesta four 7 week-old weaned...
1. Plant extracts and oils are supplemented in diets for chickens due to their antimicrobial capacities; however, little information exists whether they influence intestinal motility barrier function.2. The present study aimed determine the effect of increasing levels cinnamon bark oil (CBO; 0%, 0.038%, 0.076% 0.151%) coconut emulsions prepared with soy sunflower lecithin on contractile function enteric wall muscles jejunum ileum jejunal laying hens.3. For testing muscle contraction,...
1. Short-chain fatty acids (SCFA) exert beneficial actions in the gut; nevertheless, information about effect of SCFA on physiological responses small intestine chickens is rare.2. The aim this study was to assess 1) different molar acetate:butyrate ratios (Ac:But; Experiment 1; 78.5% acetate and 7.3% butyrate versus 71.4% 14.0% butyrate) 2) concentrations (Experiment 2; final concentration chambers: 70.5 141 µmol SCFA/ml buffer) jejunal caecal contractibility barrier function laying hens....
Abstract In the immediate time after weaning, piglets often show symptoms of gut inflammation. The change to a plant-based diet, lack sow milk, and resulting novel microbiome metabolite profile in digesta may be causative factors for observed We used intestinal loop perfusion assay (ILPA) investigate jejunal colonic expression genes antimicrobial secretion, oxidative stress, barrier function, inflammatory signaling suckling weaned when exposed “plant-oriented” (POM) representing postweaning...
Background: The Anogeissus latifolia (Combretaceae, Myrtales) bark is used to make Ghatti gum. It an indigenous tree gum India. Considering its toxicity, mutagenicity, and teratogenicity, the USA regularity status regarded ghatti as a safe ingredient in food additives due their bioavailability, extended accessibility, non-toxicity, affordable pricing, plant-based gums mucilages are main components many pharmaceutical formulations. Objective: goal of latest study was create describe new drug...