- Advanced biosensing and bioanalysis techniques
- Photonic and Optical Devices
- Analytical Chemistry and Sensors
- Advanced Biosensing Techniques and Applications
- Mechanical and Optical Resonators
- Gas Sensing Nanomaterials and Sensors
- Plasmonic and Surface Plasmon Research
- Advanced MEMS and NEMS Technologies
- Electrochemical sensors and biosensors
- Molecular Junctions and Nanostructures
- Semiconductor materials and devices
- Force Microscopy Techniques and Applications
- Semiconductor Lasers and Optical Devices
- ZnO doping and properties
- Microfluidic and Capillary Electrophoresis Applications
- Nanowire Synthesis and Applications
- Monoclonal and Polyclonal Antibodies Research
- Biosensors and Analytical Detection
- Chemokine receptors and signaling
- Semiconductor Quantum Structures and Devices
- Transition Metal Oxide Nanomaterials
- Structural Analysis of Composite Materials
- Copper Interconnects and Reliability
- Electrowetting and Microfluidic Technologies
- Glycosylation and Glycoproteins Research
Consejo Superior de Investigaciones Científicas
1991-2011
Centro Nacional de Microelectrónica
1992-2009
Universidad de Antioquia
2008-2009
Center for Research and Advanced Studies of the National Polytechnic Institute
2005
Centro Nacional de Biotecnología
2004
Universitat Autònoma de Barcelona
1991
Integrated optical sensors have become important in recent years since they are the only technology which allows direct detection of biomolecular interactions. Moreover, silicon microelectronics mass production as well fabrication nano-/macrosystems on same platform by hybrid integration sources, sensors, photodetectors and complementary metal-oxide semiconductor electronics.
The characteristics of a novel magneto-optic surface-plasmon-resonance (MOSPR) sensor and its use for the detection biomolecules are presented. This physical transduction principle is based on combination activity magnetic materials surface-plasmon resonance metallic layers. Such can produce sharp enhancement effects that strongly depends optical properties surrounding medium, allowing biosensing applications. Experimental characterizations MOSPR have shown an increase in limit by factor 3...
In this paper, we analyze the magnetoplasmonic (MP) features and sensing capabilities of Au/Fe/Au trilayer structures, as transducers magneto-optic surface plasmon resonance (MOSPR) biosensor. This biosensor, which can surpass sensitivity standard SPR sensor, is based on a MP modulation technique generated by simultaneous stimulation polaritons (SPP) transversal magneto-optical Kerr effect (TMOKE). We study activity trilayers function thickness position Fe layer. first demonstrate that kind...
Biomolecular interactions over the surface of a microcantilever can produce its bending motion via changes stress, which is referred to nanomechanical response. Here, we have studied interaction forces responsible for during formation self-assembled monolayer thiolated 27-mer single-stranded DNA on gold-coated side and subsequent hybridization with complementary nucleic acid. The immobilization probe gives mean stress 25 mN/m 23 nm microcantilevers length thickness about 200 μm 0.8 μm,...
The fabrication, characterization and packaging of novel microfluidic-optical integrated biosensors for label-free biochemical detection is presented in this paper. device consists a three-dimensional embedded microchannel network fabricated using enhanced CMOS compatible SU-8 multilevel polymer technology on top wafer containing Mach-Zehnder Interferometer (MZI) nanophotonic biosensor devices. PMMA housing provides connection to the macro-world ensures robust leakage-free flow operation...
A new hydrogen‐sensitive detector based on a Schottky diode has been fabricated. The devices have characterized by dark current‐voltage and capacitance‐voltage measurements, as function of temperature gas phase composition. At 150°C, the detection limit for hydrogen is 6 ppm in nitrogen environment 200 air.
Silicon based antiresonant reflecting optical waveguides (ARROW's) have been designed in order to obtain a high sensitive transducer for sensing applications. The sensor has an integrated Mach-Zehnder interferometer configuration. that form its structure verify two conditions: monomode behavior and surface sensitivity. In this paper, we present theoretical modeling of the propagation characteristics sensitivity ARROW structure.
In this work we present the fabrication and characterization of immunosensors based on polystyrene (PS)-multiwalled carbon nanotube (MWCNT) composites.The electrochemical properties sensors have been investigated show that surface area is increased upon addition MWCNT-PS layer.Furthermore, a plasma activation process used to partially remove PS expose MWCNTs.This results in huge increase opens up possibility binding biomolecules MWCNT wall.The MWCNTs functionalized covalently with model...
ABSTRACT Use of SPR-based biosensors is an established method for measuring molecular interactions. Their application to the study GPCRs nonetheless limited detergent-solubilized receptors that can then be reconstituted into a lipid environment. Using chemokine receptor CXCR4 and its specific ligand CXCL12, we outline here highly reproducible biosensor based on presentation surface lentiviral particles; approach simple does not require use antibodies achieve correct orientation sensorchip...
The development of an evanescent field sensor with integrated Mach-Zehnder interferometric (MZI) configuration requires the fabrication optical waveguides two main characteristics: (1) monomode behavior and (2) high surface sensitivity for sensing biomolecular interactions in a direct way (without labels). In this paper, we present experimental study optimization different parameters that will be basis highly sensitive sensor. After optimization, MZI has been fabricated some applications are...