A5061663364- Advanced Drug Delivery Systems
- Phytochemicals and Antioxidant Activities
- RNA Interference and Gene Delivery
- Bee Products Chemical Analysis
- Nanoparticle-Based Drug Delivery
- Advancements in Transdermal Drug Delivery
- Natural Antidiabetic Agents Studies
- Sirtuins and Resveratrol in Medicine
- Dermatology and Skin Diseases
- Computational Drug Discovery Methods
- Phytochemistry and biological activity of medicinal plants
- Tea Polyphenols and Effects
- Bioactive Compounds and Antitumor Agents
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Cholinesterase and Neurodegenerative Diseases
- Natural Compound Pharmacology Studies
- Plant-Derived Bioactive Compounds
- Pancreatic function and diabetes
- Curcumin's Biomedical Applications
- Alzheimer's disease research and treatments
- Electrospun Nanofibers in Biomedical Applications
- Skin Protection and Aging
- Medicinal Plant Extracts Effects
- Phytochemicals and Medicinal Plants
Erciyes University
2013-2025
Bozok Universitesi
2023-2024
Düzce Üniversitesi
2019
The study was aimed to evaluate the effectiveness of rosmarinic acid (RA) loaded ethosomes (ETHs) and liposomes (LPs) when subjected transdermal application. RA-loaded ETHs LPs were prepared, optimised, characterised. ex vivo permeation studies formulations using mouse abdominal skin performed. Antioxidant activities inhibitory effects on collagenase elastase enzymes measured. Optimised ethosomal formulation (F3) showed nanometric size range (138 ± 1.11 nm) greatest entrapment (55 1.80%),...
Diabetes mellitus (DM) is a chronic metabolic disease and the subgroup of DM called type II which most common form. The incidence increasing worldwide it focuses on several new approaches to efficiently treatment diabetes. Resveratrol (RSV) known be strong antioxidant has an insulin-like effect in streptozotocin (STZ)-induced diabetic cells. It plays active role at diabetes with reducing oxidative stress, lowering glucose levels protection beta cells are responsible for insulin secretion. In...
Yakın geçmişte Gopinath ve arkadaşları tarafından keşfedilen aspazomlar, askorbil palmitatın oluşturduğu çift tabakalı veziküler sistem olarak tanımlanmaktadır. Askorbil palmitat, askorbik asite göre daha lipofilik, kararlı biyoyararlanımı yüksek olan ester formudur. Vücutta kullanıma kadar lipit hücre zarında depolanabilen ilaç çözünürlüğünü deride permeabiliteyi artırıcı özellikleriyle aspazomları dermal uygulamada ön plana çıkaran önemli avantajlara sahiptir. Yapılan çalışmalara...
Controlled release systems containing natural compounds have been successfully applied in cosmetics as antiaging products to enhance the penetration of active through skin. In this study, we aimed develop novel ethosomal formulations a potent antioxidant, epigallocatechin-3-gallate (EGCG), and evaluate their potential for use by determining antioxidant effects. Ethosomes (ETHs) were prepared via mechanical dispersion characterized vitro terms particle size (PS), zeta (ZP), polydispersity...
Salvia aramiensis Rech. f. is a species that grows only in Hatay, Turkey and used as traditional stomachic tea. Neither the chemical composition nor potential bioactivity of plant has been investigated before. Antioxidant activity (1,1-Diphenyl-2-picrylhydrazyl Radical (DPPH●) 2,2'-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS+●) radical scavenging β-carotene/linoleic co-oxidation) 70% methanol, ethanol extracts, 2% infusion obtained from S. aerial parts were determined. The effect...
This study aims to investigate and compare the effects of insulin embryonic stem-cell (ESC) loaded liposomes (LPs) nanocochleate formulations their PEGylated forms on glucose levels. All were characterized considering particle size, zeta potential, polydispersity index encapsulation efficiencies. In-vitro that releases from was determined using Franz-type diffusion cells. A cytotoxicity test revealed none toxic cells in any concentrations. The diabetic induced with streptozotocin (STZ) then...
The Lime Basra (Citrus aurantifolia Linn., Rutaceae) plant also known as dried lime, and Limoo Omani, is used both a spice in meals an herbal tea the treatment of some diseases Middle East. It was aimed to determine biological activity screening 70% methanol, ethanol extracts infusion which were prepared from fruits. 1,1-diphenyl-2-picrylhydrazyl (DPPH●) 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS+●) radical scavenging activities, ferric reducing activity, cytotoxicity on A...
is rich in phenolic content and has powerful antioxidant antidiabetic activity. However, there are no medicinal products prepared due to this feature. Therefore, study aims characterize an