A5088387212- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Medical Imaging and Analysis
- Urological Disorders and Treatments
- Economic and Financial Impacts of Cancer
- Radiopharmaceutical Chemistry and Applications
- Urinary Bladder and Prostate Research
- Generative Adversarial Networks and Image Synthesis
- Colorectal Cancer Screening and Detection
- Cardiac Imaging and Diagnostics
- Thyroid and Parathyroid Surgery
- Genetic and Kidney Cyst Diseases
- COVID-19 diagnosis using AI
- Health Systems, Economic Evaluations, Quality of Life
- Lung Cancer Diagnosis and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Advanced X-ray and CT Imaging
- Renal and related cancers
- Renal cell carcinoma treatment
- Thyroid Disorders and Treatments
Dana-Farber Brigham Cancer Center
2024
Brigham and Women's Hospital
2024
Dana-Farber Cancer Institute
2024
National Institutes of Health
2020-2023
National Cancer Institute
2020-2021
Griffith University
2015
Chest CT is emerging as a valuable diagnostic tool for clinical management of COVID-19 associated lung disease. Artificial intelligence (AI) has the potential to aid in rapid evaluation scans differentiation findings from other entities. Here we show that series deep learning algorithms, trained diverse multinational cohort 1280 patients localize parietal pleura/lung parenchyma followed by classification pneumonia, can achieve up 90.8% accuracy, with 84% sensitivity and 93% specificity,...
The purpose of this study was to understand the extent, nature and variability current economic burden prostate cancer among Australian men. An online cross-sectional survey developed that combined pre-existing measures new questions. With few exceptions, viable acceptable participants. main outcomes were self-reported out-of-pocket costs diagnosis treatment, changes in employment status household finances. Men recruited from support groups throughout Australia. Descriptive statistical...
The purpose of this study was to prospectively evaluate Prostate Imaging Reporting and Data System version 2.1 (PI-RADSv2.1), which released in March 2019 update 2.0, for prostate cancer detection with transrectal ultrasound-MRI fusion biopsy 12-core systematic biopsy.
Patients diagnosed with high risk localized prostate cancer have variable outcomes following surgery. Trials of intense neoadjuvant androgen deprivation therapy (NADT) shown lower rates recurrence among patients minimal residual disease after treatment. The molecular features that distinguish exceptional responders from poor are not known. To identify genomic and histologic associated treatment resistance at baseline. Targeted biopsies were obtained 37 men intermediate- to high-risk before...
Abstract Purpose: For high-risk prostate cancer, standard treatment options include radical prostatectomy (RP) or radiotherapy plus androgen deprivation therapy (ADT). Despite definitive therapy, many patients will have disease recurrence. Imaging has the potential to better define characteristics of response and resistance. In this study, we evaluated multiparametric MRI (mpMRI) before after neoadjuvant enzalutamide ADT. Patients Methods: Men with localized intermediate- cancer underwent a...
ABSTRACT Localized prostate cancer is distinctively characterized by intratumoral heterogeneity, and tumors with more complex evolutionary paths display aggressive characteristics. In clinical trials of intense neoadjuvant androgen deprivation therapy (inADT), patients complete or near-complete responses experience durable remissions. However, the molecular characteristics distinguishing exceptional responders nonresponders at baseline have not been established. Here, we present integrated...
e17567 Background: Patients diagnosed with prostate cancer undergo computed tomography (CT) for pretreatment staging to rule out bone metastases. However, detection and classification of lesions on CT is challenging subject inter-reader variability. We present a cascaded deep learning algorithm automatic in patients cancer. Methods: scans from 56 histopathologically proven were included. An expert radiologist annotated the extent individual (N = 4217) labelled all regions as either benign or...
<p>Contains supplementary methods and 3 tables.</p>
<p>Contains supplementary methods and 3 tables.</p>
<div>AbstractPurpose:<p>For high-risk prostate cancer, standard treatment options include radical prostatectomy (RP) or radiotherapy plus androgen deprivation therapy (ADT). Despite definitive therapy, many patients will have disease recurrence. Imaging has the potential to better define characteristics of response and resistance. In this study, we evaluated multiparametric MRI (mpMRI) before after neoadjuvant enzalutamide ADT.</p>Patients Methods:<p>Men with...
<div>AbstractPurpose:<p>For high-risk prostate cancer, standard treatment options include radical prostatectomy (RP) or radiotherapy plus androgen deprivation therapy (ADT). Despite definitive therapy, many patients will have disease recurrence. Imaging has the potential to better define characteristics of response and resistance. In this study, we evaluated multiparametric MRI (mpMRI) before after neoadjuvant enzalutamide ADT.</p>Patients Methods:<p>Men with...
Abstract Background and purpose: Both multiparametric magnetic resonance imaging (mpMRI) prostate specific membrane antigen (PSMA)-targeting positron emission tomography (PET) have shown promise in early localization of cancer (PCa) recurrence after primary external beam radiotherapy. Detecting brachytherapy for PCa using MRI is significantly hampered by susceptibility artifacts secondary to brachy seeds. Here, we compare the efficacy 18 F-DCFPyL (2-(3-{1-carboxy-5-[(6-...
Abstract Background and purpose: Both multiparametric magnetic resonance imaging (mpMRI) prostate specific membrane antigen (PSMA)-targeting positron emission tomography (PET) have shown promise in early localization of cancer (PCa) recurrence after primary external beam radiotherapy. Detecting brachytherapy for PCa using MRI is significantly hampered by susceptibility artifacts secondary to brachy seeds. Here, we compare the efficacy 18 F-DCFPyL (2-(3-{1-carboxy-5-[(6-...
Abstract Background and purpose: Both multiparametric magnetic resonance imaging (mpMRI) prostate specific membrane antigen (PSMA)-targeting positron emission tomography (PET) have shown promise in early localization of cancer (PCa) recurrence after primary external beam radiotherapy. Detecting brachytherapy for PCa using MRI is significantly hampered by susceptibility artifacts secondary to brachy seeds. Here, we compare the efficacy 18 F-DCFPyL (2-(3-{1-carboxy-5-[(6-...
Abstract Background and purpose: Both multiparametric magnetic resonance imaging (mpMRI) prostate specific membrane antigen (PSMA)-targeting positron emission tomography (PET) have shown promise in early localization of cancer (PCa) recurrence after primary external beam radiotherapy. Detecting brachytherapy for PCa using MRI is significantly hampered by susceptibility artifacts secondary to brachy seeds. Here, we compare the efficacy 18 F-DCFPyL (2-(3-{1-carboxy-5-[(6-...