A5068578362- Transcranial Magnetic Stimulation Studies
- Visual perception and processing mechanisms
- Hearing Loss and Rehabilitation
- Sleep and related disorders
- Neuroscience and Music Perception
- Vestibular and auditory disorders
- Sleep and Wakefulness Research
- Health disparities and outcomes
- Ophthalmology and Visual Impairment Studies
- Restless Legs Syndrome Research
- Spatial Neglect and Hemispheric Dysfunction
- Retinal Development and Disorders
- Migraine and Headache Studies
- Health Education and Validation
- Stroke Rehabilitation and Recovery
- Multisensory perception and integration
- Noise Effects and Management
- Dementia and Cognitive Impairment Research
- Retinal Diseases and Treatments
- Frailty in Older Adults
- Aging and Gerontology Research
- Telemedicine and Telehealth Implementation
- Health, Nursing, Elderly Care
- Misinformation and Its Impacts
- Language Acquisition and Education
University of Beira Interior
2016-2025
Instituto Politécnico da Guarda
2019
Hospital Padre Américo
2014
University College London
1998-2002
National Hospital for Neurology and Neurosurgery
1998-2002
Our study examined the association between insomnia, and cognitive as well functional outcomes in a cohort of ischemic stroke patients. We evaluated which features were associated with development post-stroke insomnia how it might affect prognosis.157 patients retrospectively during their hospitalization Portuguese Stroke Unit re-assessed two years afterwards, at follow up appointment. collected data including clinical variables, vascular risk factors, developed after stroke, use...
Charcot–Marie–Tooth disease (CMT) comprises a clinically and genetically heterogeneous group of peripheral neuropathies characterized by progressive distal muscle weakness atrophy, foot deformities sensory loss. Following the analysis two consanguineous families affected medium to late-onset recessive form intermediate CMT, we identified overlapping regions homozygosity on chromosome 1p36 with combined maximum LOD score 5.4. Molecular investigation genes from this region allowed...
Background: Through transcranial magnetic stimulation (TMS) it is possible to change cortical excitability of the visual cortex, and influence binocular balance. The main goal our study assess effect stimulation, specifically theta burst (TBS), in a group amblyopic volunteers measuring several parameters: acuity, suppressive imbalance, stereoacuity. Methods: Thirteen aged 19 24 years, randomly split 2 groups, underwent 1 session continuous TBS, stimulating right occipital lobe. first with 8...
In order to assess higher auditory processing capabilities, long-latency evoked potentials (AEPs) were recorded synthesized musical instrument tones in 22 post-comatose patients with severe brain injury causing variably attenuated behavioural responsiveness. On the basis of normative studies, three different types spectro-temporal modulation employed. When a continuous `clarinet' tone changes pitch once every few seconds, N1/P2 are at latencies ~90 and 180 ms, respectively. Their...
Centenarians are a growing population in Europe and present significant variability motor cognitive functions. The aim of our study was to characterize health status, as well functions group Portuguese centenarians. In addition, also aimed at analyzing the relationship between burden diseases affecting elderly. Fifty-two centenarians were evaluated using Mini-Mental State Examination, short version. Walking-related parameters (velocity time spent 3 m walk test), grip strength number...
A solidão e a depressão encontram-se relacionadas com o bem-estar psicológico na velhice. Contudo, esta relação não é clara dada complexidade destas dimensões, nomeadamente da solidão. Este estudo pretende avaliar estas duas dimensões discutir sua em pessoas idosas, considerando aspetos sociodemográficos. Participaram no 213 idades entre os 65 96 anos, sendo média de 75 anos (DP=6.74). Foram utilizados como instrumentos avaliação, um questionário sociodemográfico, Escala Depressão Geriátrica...
Purpose: Translate and adapt the Convergence Insuficiency Symptom Survey (CISS) questionnaire to Portuguese language culture assess psychometric properties of translated (CISSvp). Methods: The CISS was adapted according methodology recommended by some authors. process involved two translations back-translations performed independent evaluators, evaluation these versions, preparation a synthesis version its pre-test. final (CISSvp) applied in 70 patients (21.79 ± 2.42 years) students higher...
After decades of effort, there are no effective clinical treatments to induce the recovery ischemia-injured tissues, and among several strategies that have been explored, repetitive transcranial magnetic stimulation has proven be one most promising, with beneficial effects in limb motor function, aphasia, hemispatial neglect, or dysphagia. Despite evidences, little is known about mechanisms underlying those effects. The present study aimed explore cellular molecular high-frequency (HF-rMS)...
Theta-burst stimulation (TBS) is a safe non-invasive neurostimulation technique used to improve cognitive and neuropsychiatric impairments. Combined outcome evaluation using event-related potentials (ERPs) neuropsychological tests may allow more thorough assessment of TBS treatment efficacy; however, some mixed results have been found, their use remains scarce. Our main objective was evaluate whether session the left dorsolateral prefrontal cortex (DLPFC) can impact upon performance both...
Due to its ability improve the most frequent clinical sequelae left by ischemia, repetitive transcranial magnetic stimulation has been considered a promising therapeutic strategy for stroke. Those improvements are associated with changes in neurons and their synaptic liaisons. However, hypothesis that this technique modulates astrocytes, potentiating neuroprotective capabilities, was also raised. This study aims identify effects triggered high-frequency (HF-rMS) on astrocytes contribute...
The interest in studying a specific population of centenarians who lives the country’s interior region (PT100-BI) emerged during first Portuguese systematic study about (PT100 Oporto Centenarian Study). This Portugal is predominantly rural and one regions with largest number aged people. aim this to provide information on live Beira Interior region, specifically terms their health status services they use. A total 101 (mean age: 101.1 years; SD = 1.5 years), 14 males 87 females, were...
Theta-burst stimulation (TBS) can be a non-invasive technique to modulate cognitive functions, with promising therapeutic potential, but some contradictory results. Event related potentials are used as marker of brain deterioration and evaluate TBS-related performance, its use remains scant. This study aimed bilateral inhibitory excitatory TBS effects upon neurocognitive performance young healthy volunteers, using the auditory P300' Using double-blind sham-controlled study, 51 volunteers...
There is a consensus that elderly individuals are quite vulnerable to adverse drug reactions (ADRs), and headaches one of the most frequent clinical presentations central nervous system problems in general population, which can be an ADR. The purpose our work was analyze reports “headache” associated ADRs sent Portuguese Pharmacovigilance System (PPS), also drugs were more frequently with this reaction. A retrospective analysis suspected ADR involving patients aged 65 years or older received...