Prisca Chinonso Njoku

ORCID: 0000-0002-0671-0818
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About
Contact & Profiles
Research Areas
  • Prostate Cancer Treatment and Research
  • Protein Kinase Regulation and GTPase Signaling
  • Computational Drug Discovery Methods
  • PARP inhibition in cancer therapy
  • RNA modifications and cancer
  • Cancer, Hypoxia, and Metabolism
  • Cancer Genomics and Diagnostics
  • Synthesis and biological activity
  • Brain Tumor Detection and Classification
  • Cancer Cells and Metastasis
  • Microtubule and mitosis dynamics
  • Cancer-related molecular mechanisms research
  • Cancer-related gene regulation

University of Lagos
2022-2025

University of Toledo
2024

University of Ibadan
2023

University of Benin
2023

Kwara State University
2023

Obafemi Awolowo University
2023

University of Nigeria
2023

Adekunle Ajasin University
2023

Tumor cells disseminate in various distant organs at early stages of cancer progression. These disseminated tumor (DTCs) can stay dormant/quiescent without causing patient symptoms for years or decades. dormant survive despite curative treatments by entering growth arrest, escaping immune surveillance, and/or developing drug resistance. However, these reactivate to proliferate, metastatic progression relapse, posing a threat patients' survival. It's unclear how maintain dormancy and what...

10.1016/j.canlet.2024.216899 article EN cc-by Cancer Letters 2024-04-21

Globally, the advent of new cases cancer has been steadily increasing, with rising mortality and a significant impact on economy.Most malignancy outcomes are linked to early detection, prompt diagnosis, treatment.The need for detection is crucial management.With these increasing numbers, there adoption emerging technologies such as machine learning help improve outcome management.For reasons, in this paper, we reviewed role medical imaging techniques management cancer.In general, technology...

10.4236/oalib.1110014 article EN OALib 2023-01-01

Over the years, there have been studies on significant impact of epigenetic activities that downstream effect gene expression. Amongst these is chemical modification RNA which consists over 100 types modifications. However, leading mRNA N6-methyladenosine (M6A) and it critical to cellular activity, having shown regulate stability, splicing, translocation, translation. The process involved in methylation, makes use proteins such as methyl-transferase complex (METC), serve writer. methylation...

10.1016/j.sciaf.2022.e01347 article EN cc-by Scientific African 2022-08-28

Abstract More than 19 percent of all human cancer cases globally express mutant RAS proteins, which are the most frequently altered oncogenic proteins. Targeting cells becomes difficult because these proteins and that driven by Ras mutation show very aggressive traits. KRAS is expressed among three isoforms mutation, usually occur at position 12. G12C G12D common types have been proven to target for many years. In recent times, studies started a lot food spices possess strong anticancer...

10.21203/rs.3.rs-3079675/v1 preprint EN cc-by Research Square (Research Square) 2023-06-22
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