Objectives Resilience, the ability to bounce back after adverse events may be an important factor in active aging. The 10-item version of Connor–Davidson Resilience Scale (CD-RISC10) seems suitable for aging research owing its low participant burden; however, psychometric properties have not been comprehensively reported older people. For example, no estimate exists test–retest reliability scale when used with adults. Hence, this study evaluated CD-RISC10 a large population-based sample...

Intrinsic capacity (IC) defined by the WHO refers to composite of five domains capacities. So far, developing and validating a standardized overall score concept have been challenging partly because its conceptual framework has unclear. We consider that person's IC is determined domain-specific indicators suggesting formative measurement model. To develop an applying approach assess validity. The study sample (n = 1908) consisted 57-88-year-old participants from Longitudinal Aging Study...

Whether increased life expectancy is accompanied by functional capacity in older people at specific ages unclear. We compared similar validated measures of maximal physical performance 2 population-based cohorts born and assessed 28 years apart.Participants the first cohort were 1910 1914 age 75 80 years, respectively (N = 500, participation rate 77%). Participants second 1938 or 1939 1942 1943 726, 40%). recruited using a population register all community-dwelling persons target area...

Social distancing during the COVID-19 pandemic reduced possibilities for activities of choice potentially threatening quality life (QoL). We defined QoL resilience as maintaining high and studied whether walking speed, absence loneliness, living arrangement, stress-coping ability predict among older people.Community-dwelling 75-, 80-, 85-year-old persons (n = 685) were interviewed examined in 2017-2018 followed up social 2020. assessed using OPQOL-brief scale set a cut-off 'constant high'...

In 2015, the World Health Organisation (WHO) introduced concept of intrinsic capacity (IC) as part a new public health model for healthy ageing. IC refers to overall combination an individual's physical and mental capacities, is promoted positive approach wellbeing older adults. However, there still insufficient evidence that implementing leads better care Moreover, current operationalisations lead confusion redundant research. this commentary, we discuss whether has added value geriatrics,...

Abstract Background Among older people, community mobility was reduced at the beginning of COVID-19 pandemic, but longer-term changes are unclear. Aims To study lower extremity performance and car driving as predictors in adults’ life-space mobility, autonomy participation outdoors, risk developing restricted from 2017 to 2022. Methods Life-space (scoring range 0-120) outdoors 0–20) were assessed community-dwelling individuals ( n = 657) 2017–2018 (baseline age 75, 80, or 85 years), during...

Objective Energy-saving sedentary behaviour may be an evolutionarily selected trait that is no longer advantageous. We investigated the associations between genetic liability to and incidence of most common cardiovascular disease (CVD). Methods constructed validated a genome-wide polygenic score for leisure screen time (PGS LST) as measure behaviour. performed survival analyses higher PGS LST register-based CVDs using FinnGen cohort (N=293 250–333 012). Replication exploratory were conducted...

Finland's national vitamin D fortification policy has significantly improved the population's sufficiency. This study investigates association between serum concentration and muscle health, considering impact of menopause aging in Finnish cohorts. The comprised two cohorts: 237 middle-aged women (aged 47-55 years) from Estrogenic Regulation Muscle Apoptosis (ERMA) its follow-up, 908 older adults 75, 80, 85 Active Aging (AGNES) study. Vitamin was assessed through 25-hydroxyvitamin (25(OH)D)...

Abstract Objective To evaluate cohort differences in cognitive performance older men and women born assessed 28 years apart. Methods Data this study were drawn from two age-homogeneous cohorts measured the same laboratory using standardized tests. Participants first 1910 1914 1989–1990 (Evergreen project, n = 500). second 1938 or 1939 1942 1943 2017–2018 II, 726). both at age 75 80 recruited population register. Cognitive was Digit Span test Wechsler Memory Scale (WMS), Symbol Adult...

Abstract Background Living alone is a risk factor for health decline in old age, especially when facing adverse events increasing vulnerability. Aim We examined whether living associated with higher post-fracture mortality risk. Methods Participants were 190 men and 409 women aged 75 or 80 years at baseline. Subsequent fracture incidence followed up 15 years. Extended Cox regression analysis was used to compare the associations between arrangements during first year non-fracture time. All...

Good sit-to-stand (STS) performance is an important factor in maintaining functional independence. This study investigated whether free-living STS transition volume and intensity, assessed by a thigh-worn accelerometer, associated with characteristics related to independence.Free-living accelerometry was recorded continuously for 3-7 days population-based sample of 75-, 80-, 85-year-old community-dwelling people (479 participants; women n = 287, men 192). The records were used evaluate the...

Objectives: To examine birth cohort differences in depressive symptoms and life satisfaction older men women the mechanisms underpinning possible differences. Methods: Two independent cohorts of Finnish aged 75 80 were assessed 1989-1990 (n = 617) 2017-2018 794). They reported their (CES-D), current satisfaction, evaluation until now. Results: The later-born fewer (8.6 ± 7.1 vs. 13.9 8.3) similar for subdomains symptoms. was more often mostly satisfied with now (90 70%) but not than...

Abstract Background The network approach may provide a framework for understanding intrinsic capacity (IC) as system’s underlying functioning. resilience to resist functional decline arise from the interrelationships among system components, that is, body functions or capacities. We applied analysis investigate whether interplay between different capacities differs according age and self-rated health (SRH) in older adults. Methods study sample consisted of population-based cohort...

We used a polygenic score for hand grip strength (PGS HGS) to investigate whether genetic predisposition higher muscle predicts age-related noncommunicable diseases, survival from acute adverse health events, and mortality.

The World Health Organization has introduced the construct of intrinsic capacity (IC) as an important component healthy ageing and overall well-being in older adults present study aimed to develop domain-specific composite IC scores validate these by examining their longitudinal relation with functioning.

Physiological reserve, as indicated by muscle strength and gait speed, may be especially determinant of survival in people who are exposed to a health stressor. We studied whether the association between strength/speed mortality risk would stronger time period after fracture compared other periods.Participants were population-based sample 157 men 325 women aged 75 80 years at baseline. Maximal 10-m speed maximal isometric grip knee extension tested baseline before fracture. Subsequent...

(1) Background: The purpose of this study was to evaluate the day-to-day variability and year-to-year reproducibility an accelerometer-based algorithm for sit-to-stand (STS) transitions in a free-living environment among community-dwelling older adults. (2) Methods: Free-living thigh-worn accelerometry recorded three seven days 86 (women n = 55) adults, on two occasions separated by one year, long-term consistency behavior. (3) Results: Year-to-year intraclass correlation coefficients (ICC)...

Reduced age-specific mortality and increased muscle strength walking speed of current older adults may have altered the relationships between these factors as more people be above reserve capacity threshold. We compared cross-sectional associations speed, with five-year two population-based cohorts 75- 80-year-old born 28 years apart. Maximal isometric grip knee extension were measured in 2017-2018 (n = 726). Mortality was ascertained from registers. The data same-aged studied 1989-1990...

Information about mobility and physical function may be encoded in the complexity of daily activity pattern. Therefore, pattern metrics could provide novel insight into relationship between behavior health. The purpose present study was to examine association among community-dwelling older adults 75, 80, 85 yr age.A total 309 participants wore accelerometers concurrently on thigh trunk for at least three consecutive days. Five states (lying, sitting, standing, walking, or other than walking)...

We examined whether autonomic nervous system (ANS) and postural control regulation during orthostatic test reflect physical resilience by studying their associations with maximal walking speed mortality.The participants were community-dwelling Finnish men (n = 303) women 386) aged 75, 80, 85 years at baseline. Systolic diastolic blood pressure (BP), heart rate, rate variability (HRV), respiratory sway obtained using a digital sphygmomanometer, single-channel ECG, thigh- chest-worn...

Abstract Background It is unclear how the genetics of sedentary behavior are associated with incident cardiovascular disease (CVD). We investigated associations between genetic liability to behavior, sedentariness, and four main CVD outcomes: any CVD, hypertensive diseases, ischemic heart cerebrovascular diseases. Methods Leisure screen time was used as a proxy for behavior. developed polygenic score leisure (PGS LST) based on over 890,000 variants. tested validity this against self-reported...

To examine the reciprocal associations between walking performance, physical activity (PA), and perceived autonomy in outdoor mobility 322 older adults.