- Hemoglobinopathies and Related Disorders
- Multiple Myeloma Research and Treatments
- Chronic Lymphocytic Leukemia Research
- Iron Metabolism and Disorders
- Bone and Joint Diseases
- PI3K/AKT/mTOR signaling in cancer
- Porphyrin Metabolism and Disorders
- Blood groups and transfusion
- CAR-T cell therapy research
- Acute Lymphoblastic Leukemia research
- Lymphoma Diagnosis and Treatment
- Neurological Complications and Syndromes
- Metabolism and Genetic Disorders
- Folate and B Vitamins Research
- Acute Myeloid Leukemia Research
University of California, Davis
2018
University of California Davis Medical Center
2017
Children's Hospital & Medical Center
1979
We studied 47 patients with sickle-cell anemia to determine the effect of alpha-thalassemia on severity their hemolytic anemia. diagnosed objectively by using alpha-globin-gene mapping detect deletions, studying 25 subjects normal four alpha-globin-genes, 18 three, and two. The mean hemoglobin, hematocrit, absolute reticulocyte levels (+/- S.D.) were 7.9 +/- 0.9 g per deciliter (4.9 0.6 mmol liter), 22.9 2.9 cent, 501,000 126,000 cubic millimeter, respectively, in non-thalassemic group; 9.8...
Megaloblastic anemia in childhood is uncommon and usually due to nutritional deficiency rather than congenital metabolic disease.1Individuals who subsist on diets that exclude eggs, meat, dairy products are known as vegans particularly susceptible because of a virtually complete lack dietary vitamin B12. A case profound B12deficiency the exclusively breast-fed infant vegan, manifesting triad megaloblastic with pancytopenia, aminoaciduria, neurologic changes, reviewed alert physicians this...
During the past two years, public attention has been focused on sickle cell anemia as never before. Education programs have launched, screening efforts started, and research expanded with support of private funds. In order to summarize current status knowledge disease, 36 recognized authorities were assembled in November 1971. The program was sponsored jointly by National Foundation-March Dimes Foundation for Research Sickle Cell Disease.<i>Sickle Disease: Diagnosis, Management,...