A5060602496- Fungal and yeast genetics research
- Mycotoxins in Agriculture and Food
- Fungal Biology and Applications
- Antifungal resistance and susceptibility
- Plant Pathogens and Fungal Diseases
- Plant Disease Resistance and Genetics
- Biofuel production and bioconversion
- Infectious Diseases and Mycology
- Insect Resistance and Genetics
- Microbial Metabolism and Applications
- Microbial Natural Products and Biosynthesis
- Viral Infectious Diseases and Gene Expression in Insects
- Food Quality and Safety Studies
- Microbial Community Ecology and Physiology
- Enzyme-mediated dye degradation
- Enzyme Production and Characterization
- Mycorrhizal Fungi and Plant Interactions
- Plant and animal studies
- Microbial Metabolic Engineering and Bioproduction
Woosuk University
2020-2022
Daejeon University
2019-2021
Jeonbuk National University
2006-2017
Chonbuk National University Hospital
2011
Abstract The regulator of G protein signaling (RGS) domain proteins generally attenuate heterotrimeric signaling, thereby fine-tune the duration and strength signal transduction. In this study, we characterize functions RgsD, one six RGS present in human pathogenic fungus Aspergillus fumigatus . deletion (Δ) rgsD results enhanced asexual sporulation coupled with increased mRNA levels key developmental activators. Moreover, Δ leads to spore tolerance UV oxidative stress, which might be...
The APSES transcription factor (TF) in Aspergillus species is known to govern diverse cellular processes, including growth, development, and secondary metabolism. Here, we investigated functions of the rgdA gene (Afu3g13920) encoding a putative TF opportunistic human-pathogenic fungus fumigatus deletion resulted significantly decreased hyphal growth asexual sporulation. Consistently, transcript levels key developmental regulators abaA, brlA, wetA were ΔrgdA mutant compared those wild type...
The APSES family proteins are transcription factors (TFs) with a basic helix-loop-helix domain, known to regulate growth, development, secondary metabolism, and other biological processes in Aspergillus species. In the genome of human opportunistic pathogenic fungus fumigatus, five genes predicted encode TFs present. Here, we report characterization one these genes, called mbsA (Afu7g05620). deletion (Δ) resulted significantly decreased hyphal growth asexual sporulation (conidiation),...
In eukaryotes, the MAP kinase signaling pathway plays pivotal roles in regulating expression of genes required for growth, development, and stress response. Here, we deleted mpkB gene (AFLA_034170), an ortholog Saccharomyces cerevisiae FUS3 gene, to characterize its function Aspergillus flavus, a cosmopolitan, pathogenic, aflatoxin-producing fungus. Previous studies revealed that MpkB positively regulates sexual asexual differentiation nidulans. A. deletion resulted approximately 60%...
Filamentous fungi that could be classified into Aspergillus flavus/oryzae were isolated from traditionally fermented meju commercially available in Korea. The samples analyzed for aflatoxin B1 and ochratoxin A contamination by HPLC; however, no toxin was detected. In addition, fungal bacterial metagenomic sequencing performed to analyze the microbial distribution samples. results revealed abundance of bacteria differed considerably depending on production regions fermentation conditions...
본 연구는 강원도 지역에서 채집한, 구름버섯균으로 예상되는 19종의 실험균주의 외부형태와 내부구조의 특징을 파악하여 동정하고, 구름버섯균(Trametes versicolor)의 형태적 특징과 rDNA상의 ITS염기서열간의 상관관계 유무를 확인하기 위하여 Trametes versicolor와 동일 속(Genus)에 속하며 계통학적 유연관계가 가까운 villosa KCTC06866, suaveolens KCTC 26205, hirusta KCTC26200, versicolor KCTC16781 및 KCTC26203의 4종-5균주와 함께 rDNA의 Internal Transcribed Spacers(ITS1 과 ITS2)영역의 염기서열을 비교 분석하였다. 분석결과, 채집된 실험균주는 KCTC26203과의 염기차이가 <TEX>$0{\sim}6$</TEX>개로 매우 유사한 근연한 양상을 나타내었고 계통도를 분석한 결과, 구름버섯으로 예상된 실험균주들과 종들이 단계통군을 이루어 모두...