This study aimed to understand the perceptions and experiences of suicide attempters in order suggest potential initiatives reduce burden rural India. The is based on 46 in-depth interviews with 4 focus group discussions their family members. Interview content analysis revealed information related four anticipated themes: characteristics a attempt are complex; taken public hospitals for first aid treatment; consequences attempts diverse; quality life improved after attempt. There were also...

Background: Although positive childhood experiences (PCEs) have been reported to be crucial for healthy development and better mental physical health outcomes, their epidemiology relationship with adverse (ACE) exposure in low middle-income countries, including India remain underexplored. Aims: The present study aimed ascertain the prevalence predictors of PCE understand between ACE among young adults Delhi-NCR, India. Methods: cross-sectional involved a total 1,573 (18–25 years) both sexes...

Despite growing evidence linking adverse childhood experiences (ACEs) with physical health conditions such as obesity and hypertension, research in low- middle-income countries (LMICs), including India, remains limited. This study aims to examine the relationship between ACE exposure risk of overweight/obesity hypertension among young adults Delhi-NCR, India. The present cross-sectional involved 1702 both sexes. Participants were recruited from two universities ACEs measured using...

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental increasingly recognized as an adult health concern. It linked to behavioral disinhibitions that are studied be associated with mental and physical adversities, including obesity hypertension, due potential common genetic environmental underpinnings. These connections remain underexplored, particularly in the Indian context. Hence, this study aims explore association of ADHD hypertension among young adults Delhi NCR,...

Background Cognitive impairment (CI) is a major public health concern among the geriatric population and affects around 50 million people worldwide. The prevalence of CI ranges from 5.1% to 41%, it considered an initial stage for conditions like acute dementia, Alzheimer’s disease, schizophrenia. However, diagnosing controversial due absence clear clinical criteria, leading memory complaints retained cognitive abilities being used as indicators. While several studies have examined gender...

It is a well-known fact that pro-inflammatory cytokines exert an adverse effect on conceptus and result in pregnancy failure there are mutations reported certain genes regulating the production of these Th-1 type cytokines. In view cytokine gene polymorphisms known to cause high low various proinflammatory anti-inflammatory cytokines, number studies have been performed reveal association between recurrent loss, but surprisingly contradictory results which may be attributed inclusion...

Hypospadias is a common congenital error of genital development, the frequency which increasing. As androgens have significant role in development male urethra, we sought to investigate association between 2 functional polymorphisms, CYP17-A1/A2 and SRD5A2-V89L, are involved biosynthesis testosterone dihydrotestosterone, respectively, relation hypospadias.We examined DNA samples 80 cases 100 controls for SRD5A2-V89L gene polymorphisms. Information pertaining family history, preoperative...

Abstract Objective To evaluate the effect of folate and vitamin B 12 levels on pregnancy progression outcomes. Methods The present study is a prospective follow up 100 pregnant women. Biochemical investigations (plasma homocysteine, folate, levels) were performed all women in first, second, third trimesters. Nonparametric tests used to compare differences median odds ratio analysis for assessment risk between selected biomarkers adverse Results at their first antenatal care visit found be...

Internet addiction (IA) is a growing health concern, especially among young adults. Adverse childhood experiences (ACE) have emerged as an important risk factor associated with IA. However, the relationship between IA and ACE remains understudied in India. The present study aims to explore association of cumulative domain-wise exposure adults Delhi-NCR, cross-sectional was conducted 285 (aged 18-25 years) either sex (64.2% females) residing were screened using YIAT ACE-IQ, respectively....

Purpose: Aging is one of the most important risk factors for a number human diseases. Epigenetic alterations, including changes in DNA methylation patterns, have been reported to be hallmarks aging. Being malleable process, role site-specific aging being extensively investigated; however, much less attention has given alterations global with at population level. The present study aims explore overall and sex-specific variations patterns age. Methods: A total 1,127 adult individuals (792...

Fertility is a way through which human beings biologically replace themselves in order to continue their existence on earth. The present paper therefore attempts study the factors affecting fertility among Jat women of Haryana state. A household survey was conducted 15 villages Palwal district concentration Jats found be highest and 1014 ever married were interviewed. Age at marriage, age, education status, family type, preference for male child most important that affected studied...

The genetics of the complex disorder like Diabetes Type II, which is clinically diagnosed as disease insulin resistance and impaired secretion leading to glucose homeostasis in body, remains a nightmare for geneticists. But recent progress identification most promising marker predisposition diabetes namely, TCF7L2 with its large effect size global presence various ethnically geographically different populations offers some hope robust genetic approach genome-wide association studies seem...

Background: Despite the growing realization regarding importance of adverse childhood experiences (ACEs) in adult health outcomes, this area research has received little scientific attention low- and middle-income countries, including India. Aims: To understand overall domain-specific association exposure to ACEs with current depression, anxiety, stress, well-being among young adults Delhi-NCR. Methods: This cross-sectional study was carried out 1,812 (aged 18–25 years) both sexes (68.7%...

Abstract Objectives The distribution of hypertension, type 2 diabetes, dyslipidemia, and obesity variables were studied among tribal non‐tribal populations with East Asian ancestry from northeast India. Methods Data pertaining to somatometric measurements, blood pressure, lipid profile, fasting glucose collected 1916 participants (Mizo‐422, Liangmai‐352, Meitei‐1142) both sexes older than 18 years. Two‐way ANOVA chi square analysis done understand the inter‐population prevalence differences....

The present study was carried out among two tribal populations residing in Khammam district of Andhra Pradesh, South India. A sample 132 Koyadora and 40 Nayakpod individuals all ages were collected for the purpose screening glucose-6-phosphate dehydrogenase deficiency, haptoglobins, transferrins sickle cell trait.

Recent studies have associated hysterectomies with an increased risk of several health adversities. However, the effect hysterectomy on menopausal symptoms and menopause-related quality life has not been explored much in Indian context. The present study aims to estimate prevalence severity their socio-demographic determinants among North women without hysterectomy. This cross-sectional was conducted 359 aged 40-78 years, which 266 were hysterectomy, 66 had undergone before menopause, 27...

Anthropologists have always used Glucose-6-Phosphate dehydrogenase (G6PD) deficiency and sickle cell haemoglobin to trace human evolution migratory histories of populations. The present study deals with the screening these markers among Warli population Dadra Nagar Haveli. aims enhance knowledge in realm genetics vis-à-vis two loci. Of 79 males studied, 8 (10.1%) were found be G6PD deficient. Regarding Sickle haemoglobin, sample showed no HbSS. However Heterozygotes (HbAS) constitute (12.7%)...