A5107847068- Breast Cancer Treatment Studies
- Health Systems, Economic Evaluations, Quality of Life
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Hip and Femur Fractures
- Palliative Care and End-of-Life Issues
- Frailty in Older Adults
- Nonmelanoma Skin Cancer Studies
- Peripheral Artery Disease Management
- Cancer Treatment and Pharmacology
- Traumatic Brain Injury and Neurovascular Disturbances
- Global Cancer Incidence and Screening
- Family and Disability Support Research
- Autism Spectrum Disorder Research
- Cardiac, Anesthesia and Surgical Outcomes
- Patient-Provider Communication in Healthcare
- Language Development and Disorders
- Healthcare Policy and Management
- Maternal and Perinatal Health Interventions
- Family and Patient Care in Intensive Care Units
- Mobile Health and mHealth Applications
- Breast Lesions and Carcinomas
- Health disparities and outcomes
- Thermal Regulation in Medicine
- Cutaneous Melanoma Detection and Management
University of Limerick
2015-2024
Google (United States)
2024
Cincinnati Children's Hospital Medical Center
2020
University of Edinburgh
1997-2014
Mater Misericordiae Hospital
1988-2007
International Breast Cancer Study Group
2004
Calvary Mater Newcastle Hospital
2003
University of Newcastle Australia
1996
University College London
1995
University of Glasgow
1985-1988
Purpose Axillary clearance in early breast cancer aims to improve locoregional control and provide staging information but is associated with undesirable morbidity. We therefore investigated whether avoiding axillary surgery older women would result improved quality of life (QL) similar disease-free survival (DFS) overall (OS). Patients Methods Between 1993 2002, ≥ 60 years old clinically node-negative operable whom adjuvant tamoxifen was considered indicated regardless pathologic nodal...
<h3>Importance</h3> Critical illness results in disability and reduced health-related quality of life (HRQOL), but the optimum timing components rehabilitation are uncertain. <h3>Objective</h3> To evaluate effect increasing physical nutritional plus information delivered during post–intensive care unit (ICU) acute hospital stay by dedicated assistants on subsequent mobility, HRQOL, prevalent disabilities. <h3>Design, Setting, Participants</h3> A parallel group, randomized clinical trial with...
This study shows that recent technological advancements in weapons, the policy of detente, and strategic reorientation NATO are increasing relative importance damage-limiting weapons. The resulting increases excludable benefits common-interest awareness permit allies to share defense burdens more efficiently via markets according received than was case 1960s. statistical results support our hypothesis distribution nature benefits, not industrial size, determine allies. Statistical tests...
To compare hemoglobin concentration (Hb), RBC use, and patient outcomes when restrictive or liberal blood transfusion strategies are used to treat anemic (Hb≤90 g/L) critically ill patients of age≥55 years requiring≥4 days mechanical ventilation in ICU.Parallel-group randomized multicenter pilot trial.Six ICUs the United Kingdom participated between August 2009 December 2010.One hundred (51 49 groups).Patients were a (Hb trigger, 70 g/L; target, 71-90 (90 91-110 strategy for 14 remainder ICU...
Background: The study is the first within trial cost analysis of direct versus indirect and individual group modes speech‐and‐language therapy for children with primary language impairment. Aims: To compare short‐run resource consequences four interventions alongside effects achieved measured by standardized scores on a test expressive receptive language. Methods & Procedures: design was integrated randomized controlled using 2×2 factorial (direct/indirect individual/group therapy)...
Summary. We examined hospital discharge records in 1980–81 for singleton third trimester deliveries Scotland. compared 3000 women who had previously experienced induced termination of pregnancy, and 4000 spontaneous abortion with primigravidae their second first having resulted a litebirth. Two aspects low birthweight were examined: delivery before the 37th completed week gestation, hirth weight gestational age. Our comparisons further controlled maternal height, age, sex infant, marital...
Patients who survive an intensive care unit admission frequently suffer physical and psychological morbidity for many months after discharge. Current rehabilitation pathways are often fragmented little is known about the optimum method of promoting recovery. Many patients reduced quality life.The authors plan a multicentre randomised parallel group complex intervention trial with concealment allocation from outcome assessors. required more than 48 h mechanical ventilation deemed fit...
Abstract Background Increasing numbers of patients are surviving critical illness, but survival may be associated with a constellation physical and psychological sequelae that can cause ongoing disability reduced health-related quality life. Limited evidence currently exists to guide the optimum structure, timing, content rehabilitation programmes. There is need both develop evaluate interventions support expedite recovery during post-ICU discharge period. This paper describes construct...
Purpose: Qualitative engagement with stakeholders in the development of interventions can provide insight into strategies to maximize feasibility real-life settings. We engaged (autistic adults, early childhood educators, sector leaders and policy influencers, parents autistic children, speech-language pathologists) inform an educator-led peer-mediated intervention (PMI) for preschoolers who use minimal speech that is feasible implement inclusive education care (ECEC) Method: A qualitative...
To describe the design and baseline population characteristics of an adapted lifestyle intervention trial aimed at reducing weight increasing physical activity in people Indian Pakistani origin high risk developing type 2 diabetes.Cluster, randomised controlled trial.Community-based Edinburgh Glasgow, Scotland, UK.156 families, comprising 171 with impaired glycaemia, waist sizes ≥90 cm (men) ≥80 (women), plus 124 family volunteers.Families were into either intensive 15 dietitian visits...
Abstract Background The evidence-based interventions of exercise and education have been strongly recommended as part prominent clinical guidelines for hip knee osteoarthritis (OA) more than ten years. Despite the wealth strong evidence that exists, implementation in practice is sub-optimal. This paper describes key methodologies used co-design, tailoring, evaluation IMPACT project strategies, to confront this problem across multiple levels (micro, meso, macro) public private healthcare...
A 33-yr-old woman with systemic lupus erythematosus (SLE) and concomitant development of Brown's syndrome is described. This rare complication SLE discussed.
134 patients with malignant lymphoma (follicular lymphoma, 56 patients; lymphosarcoma, 50 reticulum cell sarcoma, 28 patients) have been typed for eight well‐defined antigens of the HL—A system, major histocompatibility system in man. A significant association exists between HL—A12 and this disease group. This is most marked follicular lymphoma. The significance finding discussed.