A5008602511- Prion Diseases and Protein Misfolding
- Neurological diseases and metabolism
- Animal Disease Management and Epidemiology
- Epigenetics and DNA Methylation
- Zoonotic diseases and public health
- Trace Elements in Health
- Bacterial Identification and Susceptibility Testing
- Cancer-related gene regulation
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
Norwegian University of Life Sciences
2019-2021
National University of San Marcos
2011
The emergence of CWD in Europe 2016 and the first natural infection wild reindeer warranted disease management. This led to testing 2424 hunted or culled during 2016-2018, from infected subpopulation Nordfjella mountain range Southern Norway. To identify any association between PRNP variation susceptibility, we characterized open reading frame gene 19 positive 101 age category- sex-matched negative controls. Seven variant positions were identified: 6 single nucleotide variants (SNVs) a 24...
Abstract Infection patterns linked to age and sex are crucial predict the population dynamic effects of diseases in long‐lived species. How such demographic infection arise is often multifactorial, although cause commonly seen as a combination immune status well variation pathogen exposure. Prion particularly interesting, they do not trigger an adaptive response; hence, differences exposure behavior could be prime determinant pattern infection. In cervids, fatal prion disease, chronic...
Susceptibility to prion diseases is largely determined by the sequence of protein gene (PRNP), which encodes (PrP). The recent emergence chronic wasting disease (CWD) in Europe has highlighted need investigate PRNP diversity European deer species, better predict their susceptibility CWD. Here we report a large genetic survey six British including red (Cervus elaphus), sika nippon), roe (Capreolus capreolus), fallow (Dama dama), muntjac (Muntiacus reevesii), and Chinese water (Hydropotes...
We report the first detection of methicillin-resistant Staphylococcus aureus isolates in pigs Peru. The belong to a livestock-associated lineage previously reported North America and Europe, CC398, highly virulent USA300-like ST8-IV variant, which is predominant community-associated Latin America.
Susceptibility of cervids to Chronic Wasting Disease (CWD), a prion disease, can be modulated by variations in the protein gene (PRNP), encoding cellular (PrPC). In diseases, PrPC is conformationally converted pathogenic conformers (PrPSc), aggregates which comprise infectious prions. CWD has recently been observed its contagious form Norwegian reindeer (Rangifer tarandus) and novel, potentially sporadic forms, here called 'atypical CWD', moose (Alces alces) red deer (Cervus elaphus). To...