A5101831383- Epilepsy research and treatment
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroscience and Neuropharmacology Research
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
- Cardiovascular and Diving-Related Complications
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- Heart Rate Variability and Autonomic Control
- Pharmacological Effects and Toxicity Studies
- Anesthesia and Sedative Agents
- Tuberculosis Research and Epidemiology
- Intensive Care Unit Cognitive Disorders
- Coordination Chemistry and Organometallics
- Ophthalmology and Eye Disorders
- Cerebrovascular and Carotid Artery Diseases
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
- Health Systems, Economic Evaluations, Quality of Life
- EEG and Brain-Computer Interfaces
- Venous Thromboembolism Diagnosis and Management
- Otolaryngology and Infectious Diseases
Wayne State University
2017-2021
Neurology, Inc
2021
Detroit Medical Center
2017-2021
Henry Ford Hospital
2021
Children's Hospital of Michigan
2017
Status epilepticus (SE) is defined as ongoing seizures lasting longer than five minutes or multiple without recovery. Benzodiazepines (BZDs) are first-line agents for the management of SE. Our objective was to evaluate BZD dosing in SE patients and its effects on clinical/electrographic outcomes. A retrospective analysis conducted from a prospective database admitted university-based neurocritical care unit. The initial presentation progression refractory (RSE) non-convulsive (NCSE) with...
Coronavirus disease 2019 (COVID-19) has been associated with Acute Ischemic Stroke (AIS). Here, we characterize our institutional experience management of COVID-19 and AIS. Baseline demographics, clinical, imaging, outcomes data were determined in patients AIS presenting within March 2020 to October 2020, November August 2021, based on hospitalization volume. Of 2512 patients, 35 (1.39%, mean age 63.3 years, 54% women) had recognition was frequently delayed after symptoms (median 19.5 days)....
We present a teenage boy with recent onset of seizures, who was erroneously treated large dose an antiseizure medication as result drug mix-up. The ensuing toxicity caused vertical gaze palsy, unusual manifestation related to overdose the agent. Timely recognition error and discontinuation resulted in complete recovery baseline.
Cerebral infections have been reported after endovascular interventions such as embolization and coiling. Such complications are extremely rare only one other case has in a patient who underwent an therapy for ischemic stroke. We report 32-year-old woman, presented to our hospital with headaches lasting four weeks intervention stroke via mechanical thrombectomy. Further investigations revealed cerebral abscess the area of infarct. She was effectively treated antibiotics combination...
Objective: To develop and validate the Transformer-based Risk assessment survival model (TRisk), a novel deep learning model, for prediction of 10-year risk cardiovascular disease (CVD) in both general population individuals with diabetes. Design: Prospective open cohort study design. Setting: Primary secondary care England as provided by Clinical Practice Research Datalink (CPRD) Gold Participants: An 3 million adults aged 25 to 84 years was identified using linked primary electronic health...
Cerebral venous sinus thrombosis (CVT) is usually treated with heparin and warfarin. Newer anticoagulants are now available but the safety efficacy of newer drugs not established.
To evaluate adequacy of BZD dosing and its impact on outcome in patients with Status Epilepticus (SE).
To determine predictors of non-convulsive status epilepticus (NCSE) development in patients with generalized convulsive (GCSE) and complex partial (CPSE).
While Benzodiazepines (BZD) are first-line agents in treatment of Status Epilepticus (SE), antiepileptic drugs (AEDs) continue to be important second-line agents. Our goal is study the efficacy single and combination AEDs for SE.
Objective: We present two cases where Perampanel was used to wean patients in non-convulsive SE (NCSE) from anesthetic drugs. Background: Prolonged status epilepticus (SE) causes internalization of inhibitory gamma-amino-butyric-acid (GABA) receptors. is the first orally-active noncompetitive antagonist excitatory AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic-acid) receptor, a subtype glutamate receptor and approved for focal seizures with or without secondary generalization....
We report a patient with infectious complication of patent foramen ovale (PFO) closure device two years after implantation, leading to septic embolic stroke hemorrhagic conversion. also describe the challenges in management case, particularly deciding timing for safe anticoagulation cardiac surgery.