A5090193127- Oral Health Pathology and Treatment
- Glioma Diagnosis and Treatment
- Oral microbiology and periodontitis research
- Oral and Maxillofacial Pathology
- Forensic Entomology and Diptera Studies
- Photodynamic Therapy Research Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Nanoplatforms for cancer theranostics
- Blood Coagulation and Thrombosis Mechanisms
- Phytoplasmas and Hemiptera pathogens
- Chronic Disease Management Strategies
- Chromatin Remodeling and Cancer
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Protease and Inhibitor Mechanisms
- Soft tissue tumors and treatment
- dental development and anomalies
- Radiomics and Machine Learning in Medical Imaging
- Dental Health and Care Utilization
- Dental Trauma and Treatments
- Neuroendocrine Tumor Research Advances
- Health Systems, Economic Evaluations, Quality of Life
- Bone Tumor Diagnosis and Treatments
- Dental Implant Techniques and Outcomes
Columbia University Irving Medical Center
2023-2024
Columbia University
2023
Mahatma Gandhi Mission's Dental College and Hospital
2013-2015
Datta Meghe Institute of Medical Sciences
2010
Tobacco use is the major cause of oral cancer, which sixth most common form malignancy globally. Even in absence clinical manifestations, early changes mucosa can be detected microscopically by exfoliative cytology. The present study aimed to and compare cellular tobacco users using cytomorphometry.A total 80 subjects were included: 20 without any habits, chewers, smokers, mishri users. Smears collected from each subject, fixed, stained Papanicolaou stain. All slides evaluated for nuclear...
Loss of cell differentiation and increased cellular proliferative activity during malignant transformation leads to alteration biochemical content cells. This is reflected in the fluorescence profile tissues.(1) To evaluate efficacy autofluorescence clinical detection oral cancer. (2) correlate it with rate proliferation by analyzing argyrophilic nucleolar organizer regions (AgNORs).Autofluorescence status was studied devising a visual enhancement system using ultraviolet light, followed an...
Gingival growths are one of the most frequently encountered lesions in oral cavity. A plethora can be seen having similar clinical presentation, making diagnosis a dilemma. Peripheral odontogenic tumors rare neoplasms to occur on gingiva, common among them being peripheral fibroma (POdF). The POdF is benign, slow-growing, exophytic lesion. Although considered have recurrence potential after excision, actual rate not known due paucity reported cases. Presented here case neoplasm mimicking an...
Mucoepidermoid carcinoma (MEC) is a malignant glandular epithelial neoplasm having an unpredictable behavior and tendency to recur. Numerous parameters have been assessed predict the outcome of this lesion, but deemed inadequate, with exception tumor stage grade. In present study, we attempted correlate proliferative activity MEC its histopathological grade, using argyrophillic nuclear organizer region (AgNOR) count. Thirty cases were included in study. All slides stained hematoxylin eosin...
2056 Background: Somatic mutations in isocitrate dehydrogenase 1 (IDH) are recognized as an important prognostic factor patients with gliomas and associated longer survival. Regardless of initial grade, however, recurrence transformation into higher grade tumors is almost universal. IDH-mutant prone to develop hypermutation after exposure alkylating agents; other solid tumors, may be a predictive biomarker for PD-1 inhibitor response. In this multicenter phase 2, open label, single arm...
Abstract BACKGROUND Somatic mutations in isocitrate dehydrogenase 1 (IDH1) are an important prognostic factor patients with gliomas. IDH-mutant gliomas prone to develop hypermutation after exposure alkylating agents; other solid tumors, may be a predictive biomarker for PD-1 inhibitor response. In this study, we hypothesize that specific subgroup of would clinically benefit from nivolumab as measured by overall response rate (ORR), duration (DOR), median progression-free survival (PFS), and...
This editorial mainly focuses on the implementing Oral and Systemic health in personal healthcare system to improve patient care. It provides proper method of care sector also has been shown different approach that is beneficial adopt Transdisciplinary science policy sector. Moreover, this report shaded light result faced by after role Further, article provided opinion effects health. Bangladesh Journal Medical Science Vol.22 (Special Issue) 2023 p.1-3
Argyrophilic nucleolar organizer regions (AgNORs) is demonstrated to be useful in diagnostic pathology, mainly distinguish benign lesions from their malignant counterparts. We aimed correlate AgNORs pleomorphism with the severity of lesion oral submucous fibrosis (OSMF) and squamous cell carcinoma (OSCC) using a retrospective study on 45 archival tissues.Silver nitrate staining was performed tissues consisting 20 OSMF OSCC. Five biopsies normal mucosa acted as control. One hundred cells per...
Abstract BACKGROUND The vast amounts of genomics, epigenomics and transcriptomics data in glioblastoma (GBM) have yet to translate into better outcomes most patients. One the main challenges is how best integrate these diverse layers omics personalize improve treatment glioblastomas. Cancer master regulators are often transcription factors (TFs), which control expression many genes considered promising antitumor targets. CCAAT/enhancer-binding protein β (C/EBPβ) an abundantly-expressed...
The exploration of new methods and techniques for the diagnosis malignant tumours has always attracted attention scientists. development adjunct tools to facilitate non invasive screening high risk lesions in real time potential significantly improve our ability reduce dismal morbidity mortality oral cancer. Despite easy accessibility cavity examination, there is no satisfactory method adequately screen detect precancers non-invasively. current cancer clinically relies heavily on visual...