A5015329970- Advanced Chemical Sensor Technologies
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Pesticide Exposure and Toxicity
- Inhalation and Respiratory Drug Delivery
- Pesticide and Herbicide Environmental Studies
- Air Quality and Health Impacts
- Bee Products Chemical Analysis
- Carcinogens and Genotoxicity Assessment
- Insect and Pesticide Research
- Analytical Chemistry and Chromatography
- Phytochemicals and Antioxidant Activities
- Fungal Plant Pathogen Control
- Effects and risks of endocrine disrupting chemicals
- Cancer, Stress, Anesthesia, and Immune Response
- Salivary Gland Disorders and Functions
- Infection Control and Ventilation
- Aerosol Filtration and Electrostatic Precipitation
- Heavy Metals in Plants
- Microbial Metabolism and Applications
- Air Quality Monitoring and Forecasting
- Potato Plant Research
- Dyeing and Modifying Textile Fibers
- Ubiquitin and proteasome pathways
- Sexual Differentiation and Disorders
Institute for Medical Research and Occupational Health
2017-2024
Philip Morris International (Switzerland)
2021-2022
Abstract In this 28 day-study, we evaluated the effects of herbicide glyphosate administered by gavage to Wistar rats at daily doses equivalent 0.1 acceptable operator exposure level (AOEL), 0.5 consumer intake (ADI), 1.75 (corresponding chronic population-adjusted dose, cPAD), and 10 mg kg −1 body weight (bw) 100 times AOEL). At end each treatment, liver weights were measured compared with their baseline values. DNA damage in leukocytes tissue was estimated alkaline comet assay. Oxidative...
The isolation of keratin from poultry feathers using subcritical water was studied in a batch reactor at temperatures (120–250 °C) and reaction times (5–75 min). hydrolyzed product characterized by FTIR elemental analysis, while the molecular weight isolated determined SDS-PAGE electrophoresis. To determine whether disulfide bond cleavage followed depolymerization protein molecules to amino acids, concentration 27 acids hydrolysate analyzed GC/MS. optimal operating parameters for obtaining...
We studied the potential role of exposure to various metal(oid)s (As, Cd, Cr, Hg, Ni, and Pb) in prostate cancer. Two cohorts were established: Croatian cohort, consisting 62 cases 30 controls, Serbian 41 61 controls. Blood/serum samples collected. Levels investigated metal(oid)s, parameters oxidative stress, prostate-specific antigen (PSA) determined collected samples. A comparison measured between 103 cancer patients 91 control men from both showed significantly higher blood SOD, GPx...
The effect of maternal smoking as a source exposure to toxic metals Cd and Pb on superoxide dismutase (SOD) glutathione peroxidase (GPx) activity, metallothionein (MT), Cd, Pb, Cu, Fe, Mn, Se Zn concentrations were assessed in umbilical cord blood placenta 74 healthy mother-newborn pairs after term delivery. Sparse discriminant analysis (SDA) was used identify elements with the strongest impact SOD, GPx MT measured compartments, which then quantified by multiple regression analysis. SOD...
In vitro screening for pharmacological activity of existing drugs showed chloroquine and hydroxychloroquine to be effective against severe acute respiratory syndrome coronavirus 2. Oral administration these compounds obtain desired pulmonary exposures resulted in dose-limiting systemic toxicity humans. However, drug delivery enables direct rapid higher local tissue concentrations target tissue. this work, inhalable formulations thermal aerosolization were developed, their physicochemical...
The ongoing outbreak of coronavirus disease 2019 (COVID-19), triggered by the rapid community spread severe acute respiratory syndrome 2 (SARS-CoV-2), has brought forward need for speedy testing and manufacturing face masks global use. Overwhelmed fast-growing demand disposable masks, many governments have recommended use of, elaborated design criteria for, reusable that are meant to slow down transmission SARS-CoV-2 in general population. Using aerosol particle size spectrometers, we...
Inhalation as a route for administering drugs and dietary supplements has garnered significant attention over the past decade. We performed real-time analyses of aerosols using secondary electrospray ionization (SESI) technology interfaced with high-resolution mass spectrometry (HRMS), primarily developed exhaled breath analysis goal to detect main aerosol constituents. Several commercially available inhalation devices containing caffeine, melatonin, cannabidiol, vitamin B12 were tested....
Disruption of element homeostasis may contribute to increased susceptibility men cancer development. Whether environmental low-level metal exposure could the pathogenesis testicular is unknown. Comparison level 18 elements in whole blood, serum and urine parameters oxidative stress/antioxidant status between with germ cell tumors (TGCT) healthy showed significant difference groups most parameters. The results linear discriminant analysis a discrimination rate 96% indicated blood Ca, Co, Cu,...
Garlic is a valuable source material for medicines due to its known antitumor, hypolipidaemic, antioxidant, and immunomodulatory effects. This study compares the protective effects of conventionally grown (CG) in vitro propagated garlic (PG) against hydrogen peroxide-induced cytotoxicity HepG2 cells their antioxidant activity. used this was obtained by planting cloves or transplants PG directly field. At end vegetation period, CG were sampled extracts prepared experiment. Compared bulbs,...
Inhalation as a route for administering drugs and dietary supplements has garnered significant attention over the last decade. We performed real-time analysis of aerosols using secondary electrospray ionization (SESI) technology interfaced with high-resolution mass spectrometry (HRMS), primarily developed exhaled breath goal to detect main aerosol constituents. Several commercially available inhalation devices containing caffeine, melatonin, cannabidiol, vitamin B12 were tested. Chemical...