A5022605562- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Malaria Research and Control
- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Crystallography and molecular interactions
- Chemical Synthesis and Analysis
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
- Chemical Synthesis and Reactions
- Synthesis of Tetrazole Derivatives
- Computational Drug Discovery Methods
- Covalent Organic Framework Applications
- Click Chemistry and Applications
- Synthesis and Catalytic Reactions
- Phenothiazines and Benzothiazines Synthesis and Activities
- Radioactive element chemistry and processing
- Crystal structures of chemical compounds
- HIV/AIDS drug development and treatment
- Metal-Organic Frameworks: Synthesis and Applications
- RNA Interference and Gene Delivery
- Lanthanide and Transition Metal Complexes
- Nanomaterials for catalytic reactions
- Synthesis and Biological Evaluation
- Fluorine in Organic Chemistry
University of Delhi
2016-2025
NOAA Chemical Sciences Laboratory
2019
Banaras Hindu University
2009-2015
University of Copenhagen
2001-2004
Indian Institute of Science Bangalore
1995-2001
University of Allahabad
1992-1993
The University of Texas Medical Branch at Galveston
1985
Bhabha Atomic Research Centre
1968-1975
Peptide nucleic acid (PNA) oligomers were conjugated to cell-penetrating peptides: pAnt, a 17-residue fragment of the Drosophila protein Antennapedia, and pTat, 14-amino HIV Tat. A 14-mer PNA was attached peptide by disulfide linkage or maleimide coupling. The uptake (directly indirectly, via biotin) fluorescein-labeled peptides, PNAs, PNA-peptide conjugates studied fluorescence microscopy, confocal laser scanning fluorometry in five cell types. In SK-BR-3, HeLa, IMR-90 cells, Tlys...
An ecofriendly, magnetically retrievable amine-functionalized SiO2@Fe3O4 catalyst was successfully synthesized and affirmed by several physicochemical characterization tools, such as scanning electron microscopy (SEM), transmission (TEM), Fourier-transform infrared spectroscopy (FT-IR), vibrating sample magnetometry (VSM), energy-dispersive X-ray (EDX), powder diffraction. Thereafter, the catalytic performance of this environmentally benign NH2@SiO2@Fe3O4 investigated in one-pot...
In this work, a new metal-oxide-based metal organic framework composite, Mn3O4@ZIF-67 (MnZNC), has been developed. Initially, ZIF-67 (ZNC) was prepared via the solvothermal approach at room temperature and further integrated with as-prepared Mn3O4 nanoparticles to attain (MnZNC) catalyst characterized by FT-IR, PXRD, SEM, TEM, FESEM, EDX mapping, ICP–MS, XPS, DLS analysis, TGA, BET analysis. The MnZNC used for acetylation reaction of C–O bond alcohol N–H amine under neat conditions produce...
Gene function studies in bacteria lag behind progress genome sequencing, part because current reverse genetics technology based on disruption does not allow subtle control of gene expression for all genes a range species. Essential and clustered regions are particularly problematic. Antisense offers an attractive alternative microbial genomics. Unfortunately, lack RNAi mechanisms conventional oligonucleotides taken up efficiently. However, Escherichia coli, efficient gene-specific antisense...
The recent advancement in the field of sensing ensembles for nitroaromatics.
Tetrazoles are synthetic organic heterocyclic compounds comprising of high nitrogen content among stable heterocycles. Tetrazoles, chiefly 5-substituted 1H-tetrazoles have been used as a bioisosteric replacement for carboxylic acids in medicinal chemistry. Various clinical drugs, including losartan, cefazolin, and alfentanil, contain the tetrazole moiety. There significant developments synthesis 1H-tetrazoles. Researchers still working to develop more efficient ecofriendly methods their...
Herein, we propose a fast and scalable synthesis of triazine based hierarchically conjugated covalent organic polymer under solvent additive free conditions through single step process.
In this review, we have summarised the significant advances made in triazine-based COP synthetic strategies and their catalytic advancements. Synthetic methodologies are discussed a simplistic way to create better understanding for future modification of these methods.
Chalcone derivatives were evaluated for their antifilarial activity on Setaria cervi using glutathione- S -transferase (GST) as a drug target. The compounds 1-(4-benzotriazol-1-yl-phenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (5), and 3-(4-methoxyphenyl)-1-(4-pyrrolidin-1-yl-phenyl) prop-2-en-1-one (7) showed significant suppression ( P < 0.01) in GST of adult female parasite extract at 3 μM concentration vitro . However, was detected along with depletion GSH level. Except Compounds 1 2, all...
CeO2 nanoparticles exposed in (100) and (111) surfaces have been synthesized explored as a heterogeneous catalyst for the first time oxidation of para-xylene to terephthalic acid. The synthesis catalysis reaction was environmental friendly, where water used solvent. Ceria were with controlled size 15 nm high surface area 268 m2 g−1 magnitude. These particles exploited novel aqueous phase bypass all hazardous steps involve manufacture industrially important result shows formation 30–40% acid...