A5020263458- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Ion Transport and Channel Regulation
- Infant Development and Preterm Care
- Urinary Bladder and Prostate Research
- Childhood Cancer Survivors' Quality of Life
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Thermoregulation and physiological responses
- Adipokines, Inflammation, and Metabolic Diseases
- Traumatic Brain Injury Research
National Research Centre
2021-2025
Recently, angiotensin-converting enzyme 2 (ACE2) gene has emerged as a potential candidate for susceptibility to SARS-CoV-2 infection. We investigated whether ACE2 G8790A (rs2285666) polymorphism could be genetic marker COVID-19 and disease severity in Egyptian children adolescents. This was prospective case-control study included 580 cases diagnosed with COVID-19, matched control The genotyped using polymerase chain reaction (PCR) serum level measured by ELISA. A/A genotype A-allele were...
To date, the cytokine profile in children and adolescent with novel coronavirus disease 2019 (COVID-19) has not been reported.We investigated serum levels of a panel key cytokines COVID-19 pneumonia primary focus on "cytokine storm" such as interleukin (IL)-1β, IL-6, IL-17, IL-2, IL-4, IL-10, interferon (IFN-γ), tumor necrosis factor (TNF)-α, two chemokines interferon-inducible protein-10 (IP-10) IL-8. We also studied whether these could be potential markers for illness severity...
Nocturnal enuresis can be frustrating for children and their families as the child ages. Our aim is to evaluate urine aquaporin 2 (AQP-2) a noninvasive biomarker of water balance in with primary monosymptomatic nocturnal (PMNE).Material methods: The study included 90 children; sixty-eight suffering from PMNE aged (9.57 ± 2.16) years 22 healthy good toilet control, matched sex age. All enuretic were subjected complete history taking, clinical evaluation, bed wetting diary. Serum arginine...
Background and Objectives: Metabolic syndrome (MetS), one of the most serious global health issues, is considered chronic inflammatory states.Chemerin, Il-18 Il-1 beta adipocytokines, plays an important role in linking Met S inflammation.Few studies are conducted Egypt to disclose chemerin, as combined biomarkers increase its diagnostic accuracy.So aim our study was evaluate serum chemerin for early detection metabolic due different genetic environmental backgrounds. Methods:The enrolled 171...
Abstract Background Traumatic brain injury (TBI) in children is a significant health burden worldwide. Children aged 0 to 4 years have the highest incidence of TBI among non-elderly. These suffer from long term neurological deficits that compromise their quality life and daily living activities. Objective To determine developmental outcomes infants with TBI. Subjects Methods A prospective descriptive study on was conducted. Developmental by Age Stage Questionnaire 3rd edition (ASQ-3)...