James Dunning

ORCID: 0000-0002-1194-0108
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About
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Research Areas
  • Myofascial pain diagnosis and treatment
  • Acupuncture Treatment Research Studies
  • Musculoskeletal pain and rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Shoulder Injury and Treatment
  • Sympathectomy and Hyperhidrosis Treatments
  • Pain Mechanisms and Treatments
  • Pain Management and Placebo Effect
  • Temporomandibular Joint Disorders
  • Botulinum Toxin and Related Neurological Disorders
  • Laser Applications in Dentistry and Medicine
  • Sports injuries and prevention
  • Spinal Fractures and Fixation Techniques
  • Phonocardiography and Auscultation Techniques
  • Shoulder and Clavicle Injuries
  • Music Therapy and Health
  • Migraine and Headache Studies
  • Cardiac Health and Mental Health
  • Spinal Dysraphism and Malformations
  • Hip disorders and treatments
  • Ophthalmology and Eye Disorders
  • Pregnancy-related medical research
  • Heart Rate Variability and Autonomic Control
  • Elbow and Forearm Trauma Treatment
  • Medical research and treatments

American Academy of Arts and Sciences
2013-2025

Universidad Rey Juan Carlos
2017-2024

Salford Royal Hospital
2015

Nova Southeastern University
2015

Montgomery Botanical Center
2008

University of Birmingham
2008

University of Missouri
2002

MRC Biostatistics Unit
1999

Papworth Hospital
1999

Birmingham City Hospital
1999

Objective: The purpose of this study was to examine the psychometric properties neck disability index (NDI) and numeric pain rating scale (NPRS) in patients with (NP) without concomitant upper extremity (UE) symptoms. Design: A secondary analysis 107 NP UE Test-retest reliability, construct validity, area under curve (AUC), minimum detectable change (MDC), clinically important difference (MCID) were calculated.Results: NDI exhibited excellent reliability (ICC = 0.88; [0.63 0.95]), while NPRS...

10.1080/09593985.2018.1471763 article EN Physiotherapy Theory and Practice 2018-06-01

Randomized clinical trial.To compare the short-term effects of upper cervical and thoracic high-velocity low-amplitude (HVLA) thrust manipulation to nonthrust mobilization in patients with neck pain.Although HVLA are common interventions for management pain, no studies have directly compared both pain.Patients completed Neck Disability Index, numeric pain rating scale, flexion-rotation test measurement C1-2 passive rotation range motion, craniocervical flexion deep flexor motor performance....

10.2519/jospt.2012.3894 article EN Journal of Orthopaedic and Sports Physical Therapy 2011-09-30

Although commonly utilized interventions, no studies have directly compared the effectiveness of cervical and thoracic manipulation to mobilization exercise in individuals with cervicogenic headache (CH). The purpose this study was compare effects CH. One hundred ten participants (n = 110) CH were randomized receive both 58) or 52). primary outcome intensity as measured by Numeric Pain Rating Scale (NPRS). Secondary outcomes included frequency, duration, disability Neck Disability Index...

10.1186/s12891-016-0912-3 article EN cc-by BMC Musculoskeletal Disorders 2016-02-06

Objective Perform a clinimetric analysis of the visual analogue scale (VAS) and active pain-free mouth opening (PFMO) in patients with muscular temporomandibular disorder (mTMD).

10.1080/08869634.2025.2464227 article EN cc-by-nc-nd CRANIO® 2025-02-10

Self-reported disability and pain intensity are commonly used outcomes in patients with cervicogenic headaches. However, there is a paucity of psychometric evidence to support the use these self-report for individuals treated Therefore, it unknown if measures reliable, responsive, or result meaningful clinically important changes this patient population.A secondary analysis randomized clinical trial (n = 110) examining effects spinal manipulative therapy without exercise Reliability,...

10.1177/0333102418772584 article EN Cephalalgia 2018-04-19

Study Design Randomized, single-blinded, multi-center, parallel-group trial. Objectives To compare the effects of adding electrical dry needling into a program manual therapy, exercise and ultrasound on pain, function related-disability in individuals with plantar fasciitis (PF). Background The isolated application needling, exercise, has been found to be effective for PF. However, no previous study investigated combined effect these interventions this population. Methods One hundred eleven...

10.1371/journal.pone.0205405 article EN public-domain PLoS ONE 2018-10-31

Cardiovascular diseases are the leading cause of death and comorbidity worldwide. High blood pressure resting heart rate risk factors (or vital signs) critical to cardiovascular health, patient safety, medical management. Physiotherapists play a fundamental role in factor identification, early diagnosis, subsequent management disease. To date there is limited research Europe investigating level knowledge skills possessed by physiotherapists regarding disease screening. Three studies...

10.1186/s12891-022-05696-w article EN cc-by BMC Musculoskeletal Disorders 2022-08-04

We have used flash photolysis of caged Ca 2+ and membrane capacitance measurements to probe exocytosis in chromaffin cells at low concentrations intracellular ([Ca ] i ) (<10 μM). observed a small pool granules that is more sensitive [Ca than the previously described “readily releasable pool.” Upon activation PKC, this “highly -sensitive pool” enhanced size greater extent readily but eliminated upon expression C-terminal deletion mutant (Δ9) synaptosome-associated protein 25 kDa...

10.1073/pnas.242624699 article EN Proceedings of the National Academy of Sciences 2002-11-21

Objectives: To compare the effects of adding electrical dry needling into a manual therapy (MT) and exercise program on pain, stiffness, function, disability in individuals with painful knee osteoarthritis (OA). Materials Methods: In total, 242 participants (n=242) OA were randomized to receive 6 weeks needling, MT, (n=121) or MT (n=121). The primary outcome was related-disability as assessed by Western Ontario McMaster Universities (WOMAC) Osteoarthritis Index at 3 months. Results:...

10.1097/ajp.0000000000000634 article EN cc-by-nc-nd Clinical Journal of Pain 2018-06-01

Thoracic spine thrust manipulation has been shown to improve patient-rated outcomes for individuals with neck pain. However, there is limited evidence of its effectiveness in patients cervical radiculopathy.To compare the immediate and short-term effects thoracic those a sham radiculopathy.In this multicenter randomized controlled trial, participants radiculopathy were receive either (n = 22) or 21) spine. Outcomes measured at baseline, immediately after treatment, follow-up 48 72 hours...

10.2519/jospt.2019.8150 article EN Journal of Orthopaedic and Sports Physical Therapy 2019-04-25

Background Currently, there is conflicting clinimetric data on the patient-rated tennis elbow evaluation (PRTEE) and a paucity of evidence regarding reliability, validity, responsiveness numeric pain rating scale (NPRS), function (TEFS) in patients with lateral tendinopathy.

10.1080/09593985.2025.2450090 article EN cc-by-nc Physiotherapy Theory and Practice 2025-01-10

Degenerative cervical myelopathy (DCM) is a clinical syndrome characterized by progressive compression of the spinal cord. DCM often looks like common symptoms aging or bilateral carpal tunnel in its early stages, requiring careful differential diagnosis. Identifying real challenge as no validated screening tools are available for making Potentially, individuals with may experience misdiagnosis substantial diagnostic delays, an enhanced risk irreversible neurological consequences if not...

10.1080/10669817.2025.2465728 article EN cc-by-nc-nd Journal of Manual & Manipulative Therapy 2025-03-04

Background: Chemotherapy-induced peripheral neuropathy (CIPN) affects 20-85% of individuals exposed to neurotoxic chemotherapeutic agents. Perineural electrical dry needling (PEDN) and neural mobilization (NM) interventions may be beneficial in the management chronic neurogenic pain; however, there is a paucity research on efficacy both for CIPN. Methods: Three patients were referred an outpatient physical therapy clinic with neuropathic pain associated Each underwent PEDN NM twice weekly...

10.3390/jcm14072318 article EN Journal of Clinical Medicine 2025-03-28

There are a number of biochemical, biomechanical, endocrinological and neurovascular mechanisms underpinning the anti-nociceptive anti-inflammatory effects dry needling (DN). While myofascial trigger points likely play role in peripheral pain, diagnostic tool for localizing them has not been validated, DN studies that have targeted to elicit localized twitch responses reported mixed results. Therefore, mechanism responsible DN-mediated analgesia may be more complicated. activates...

10.4172/2329-9096.1000327 article EN cc-by International Journal of Physical Medicine & Rehabilitation 2016-01-01

The popping produced during high-velocity, low-amplitude (HVLA) thrust manipulation is a common sound; however to our knowledge, no study has previously investigated the location of cavitation sounds upper cervical spine. primary purpose was determine which side spine cavitates C1-2 rotatory HVLA manipulation. Secondary aims were calculate average number pops, duration manipulation, and single cavitation.Nineteen asymptomatic participants received two manipulations targeting right left...

10.1186/1471-2474-14-24 article EN cc-by BMC Musculoskeletal Disorders 2013-01-15

Neck pain is one of the most common musculoskeletal disorders in clinical practice. However neck may mask more serious pathology. Although uncommon physiotherapy practices, it possible to encounter rare and extremely life-threatening conditions, such as craniovertebral congenital anomalies. Basilar invagination an abnormality where odontoid peg projects above foramen magnum commonest malformation craniocervical junction. Its prevalence general population estimated be 1 %. Furthermore, a...

10.1186/s12891-015-0847-0 article EN cc-by BMC Musculoskeletal Disorders 2016-01-11

BACKGROUND CONTEXTSpinal manipulation, spinal mobilization, and exercise are commonly used in individuals with cervicogenic headache (CH). Dry needling is being increasingly the management of CH. However, questions remain about effectiveness these therapies how they compare to each other.PURPOSEThe present study aims combined effects manipulation dry mobilization on pain disability CH.STUDY DESIGN/SETTINGRandomized, multicenter, parallel-group trial.PATIENT SAMPLEOne hundred forty-two...

10.1016/j.spinee.2020.10.008 article EN cc-by-nc-nd The Spine Journal 2020-10-13

High-velocity low-amplitude thrust spinal manipulation (SM) is a recommended and commonly used manual therapy intervention in physiotherapy. Beliefs surrounding the safety effectiveness of SM have challenged its use, even advocated for abandonment. Our study aimed to investigate knowledge beliefs by Italian physiotherapists compared with similar practitioners other countries.

10.1186/s12998-022-00449-x article EN cc-by Chiropractic & Manual Therapies 2022-09-12
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