A5035382778- Hemoglobinopathies and Related Disorders
- Blood groups and transfusion
- Iron Metabolism and Disorders
- Blood disorders and treatments
- Biotin and Related Studies
Charité - Universitätsmedizin Berlin
2014-2024
Vivantes Klinikum
2014
Sickle cell disease (SCD) does not occur in the indigenous German population, but with increasing number of immigrants from countries at high risk for hemoglobinopathies, question emerges whether or a newborn screening program (NBS) SCD should be initiated Germany anyhow. We have recently shown that Berlin, city very large immigrant incidence is considerable, our findings are insufficient to make decision country as whole. In this paper we will show body epidemiological data can generated...
Newborn screening is an important public health measure of secondary prevention. With the increasing number target conditions, there a growing demand to optimize laboratory processes save patient material and work cost-effectively. Here, we report adaption commercially available SpotOn Clinical Diagnostics tandem mass spectrometry test kit detect hemoglobin fragments as well substrate-product pairs biotinidase porphobilinogen synthase at once. The presence specific peptides enzyme activities...