A5003976186- Caveolin-1 and cellular processes
- Liver physiology and pathology
- Cancer, Lipids, and Metabolism
- Pluripotent Stem Cells Research
- Retinopathy of Prematurity Studies
- Congenital heart defects research
- Microtubule and mitosis dynamics
- Glycosylation and Glycoproteins Research
- Neonatal Respiratory Health Research
- Renal and related cancers
- Birth, Development, and Health
- Drug Transport and Resistance Mechanisms
- Lipid metabolism and disorders
Mersin Üniversitesi
2019
Massachusetts Eye Research and Surgery Institute
2019
Dokuz Eylül University
2009-2014
Caveolin-1 is the main component of caveolae membrane structures and has different roles during tumorigenesis in cancer types with varying expression profiles, indicating that role caveolin-1 varies according to tumor type. In this study, we investigated hepatocellular carcinogenesis.We analyzed 96 carcinoma (HCC), 29 cirrhosis, 20 normal liver tissues 9 HCC cell lines by immunostaining western blotting, respectively. After was stably transfected HepG2 Huh7 cells, effects on cellular...
Abstract Background Hepatocyte growth factor (HGF) induced c-Met activation is known as the main stimulus for hepatocyte proliferation and essential liver development regeneration. Activation of HGF/c-Met signaling has been correlated with aggressive phenotype poor prognosis in hepatocellular carcinoma (HCC). MUC1 a transmembrane mucin, whose over-expression reported most cancers. Many oncogenic effects are believed to occur through interaction molecules. To clarify role signaling, we...
c-Met, the receptor for Hepatocyte Growth Factor (HGF), overexpressed and deregulated in Hepatocellular Carcinoma (HCC). Caveolin 1 (CAV1), a plasma membrane protein that modulates signal transduction molecules, is also HCC. The aim of this study was to investigate biological clinical significance co-expression activation c-Met CAV1 We showed were co-localized HCC cells HGF treatment increased association. HGF-triggered caused concurrent rise both phosphorylation expression CAV1. Ectopic...
Purpose: To determine the effect(s) of vascular endothelial growth factor (VEGF), VEGF receptor-2 (VEGFR-2), hepatocyte (HGF), and HGF receptor (c-Met) polymorphisms on progression/regression retinopathy prematurity (ROP) in premature infants.
Amaç: Amniyotik sıvı farklı seviyelerde kendini yenileyebilen hücre gruplarından oluşmaktadır ve bu hücrelerin kök özellikleri henüz tam olarak karakterize edilmemiştir. Son yıllarda amniyotik hücreleri (AFC) rejenaratif tıp için umut veren kaynağı görülmektedir. AFC’ler transfeksiyonel kimyasal stratejiler ile indüklenmiş pluripotent (iPSC)’ler oluşturmak terminal farklılaşmış hücrelerden daha kolay etkili bir şekilde yeniden programlanabilirler. Fakat AFC’lerin potansiyelleri soylarına...