Igor N. Khvorostov

ORCID: 0000-0002-1370-6876
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About
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Research Areas
  • Congenital Diaphragmatic Hernia Studies
  • Intestinal Malrotation and Obstruction Disorders
  • Intestinal and Peritoneal Adhesions
  • Hernia repair and management
  • Abdominal Surgery and Complications
  • Appendicitis Diagnosis and Management
  • Tracheal and airway disorders
  • Congenital gastrointestinal and neural anomalies
  • Esophageal and GI Pathology
  • Neonatal Respiratory Health Research
  • Infant Nutrition and Health
  • Pelvic floor disorders treatments
  • Gastrointestinal disorders and treatments
  • Congenital Anomalies and Fetal Surgery
  • Breastfeeding Practices and Influences
  • Acute Lymphoblastic Leukemia research
  • Diverticular Disease and Complications
  • Gynecological conditions and treatments
  • Neuroblastoma Research and Treatments
  • S100 Proteins and Annexins
  • Pancreatitis Pathology and Treatment
  • Gastrointestinal motility and disorders
  • Neonatal Health and Biochemistry
  • Intraperitoneal and Appendiceal Malignancies
  • Immune responses and vaccinations

Russian Children's Clinical Hospital
2024

City Clinical Hospital
2024

Center for Children
2022

Volgograd State Medical University
2007-2022

Ministry of Health of the Russian Federation
2021

Scientific Center of Children's Health
2021

The lecture presents modern information about embryogenesis, associated anomalies, diagnosis, and treatment of various forms anorectal malformations (ARM) in children. During the initial examination ARM children authors recommend following sequence actions for a neonatologist surgeon: catheterization esophagus order to exclude combined esophageal atresia; survey radiography abdominal organs direct or lateral projections concomitant duodenal atresia, dilated intestinal loops primary...

10.46563/1560-9561-2022-25-1-52-60 article EN Russian Pediatric Journal 2022-03-15

Abstract We present a case of tubular esophageal duplication in 3-day-old female newborn (38 weeks, 2,500 g) without concomitant abnormal development. Esophageal was diagnosed based on the clinical picture, direct laryngoscopy, esophagography and computed tomography. The duplicated esophagus resected by thoracoscopy leaving orthotopic place. Isolation from pharynx performed via separate cervical incision. After follow-up period 20 months, child returned to normal growth

10.1055/s-0042-1742594 article EN cc-by European Journal of Pediatric Surgery Reports 2022-01-01

L-asparaginase is one of the most effective drugs in pediatric and adult acute lymphoblastic leukemia treatment. But drug side effects are an important problem. pancreatitis pancreatic necrosis not common (2–18 %) complication, but high chance severe disease with fatal outcome make to bring careful attention oncologists-hematologists, surgeons, intensivists, radiologists. Recognizing multidisciplinary importance this problem, at June 21 st , 2023 Morozov Children’s Clinical hospital a Round...

10.17650/1818-8346-2024-19-2-141-146 article EN cc-by Oncohematology 2024-04-01

A comprehensive study of the state spincter muscle complex in children after surgical correction anorectal malformations was carried out,including MRI structure complex,fecal continence on Rintala scale, manometric studies anal function.The poor development complexwas characterized by a decrease (p < 0,05) average values relative width puborectal (PRWR) to 0,14 ± 0,03, for external sphincter (EASWR) 0,12 0,02, which turned out be 2,4 times lower than patients with excellent and good...

10.19163/1994-9480-2020-2(74)-95-99 article EN Journal of Volgograd State Medical University 2020-02-15

Objective: Chronic appendicitis (CA) is a diagnosis characterized by long-standing right lower quadrant pain. We analyzed clinical, morphological, and immunohistochemical studies of the appendix to confirm adequacy surgery for CA in children with chronic Patients Methods: carried out comparative clinical presentations results morphological remote 55 recurrent pain (CRLQP). Results: Morphological revealed three types changes appendix. Type 1 (n = 21)-chronic inflammation. Inflammatory...

10.1089/lap.2021.0348 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2021-11-17

The chronic recurrent abdominal syndrome (CRAS) in the right lower fossa children is believed not to be independent nosological unit and diagnosed as an exception. We carried out comparative studies of clinical picture, results morphological immunohistochemical remote appendicitis 55 CRAS 35 with acute destructive appendicitis. low prognostic significance appendicular scales for determination indications surgical treatment was established. Morphological examination most cases revealed signs...

10.18821/1560-9561-2017-20-5-270-276 article EN Russian Pediatric Journal 2019-04-30

The result of the surgical treatment a newborn infant with congenital diaphragmatic hernia complicated by pulmonary hypertension and ischemic lesion small intestine is presented. Using technology intestinal exteriorization after conversion thoracoscopic access to laparotomy, plastic surgery left dome diaphragm, moving changed loops into silo sewn edges laparotomy wound allowed avoiding serious complications in postoperative period. 7 days first operation, bowel were immersed abdominal...

10.18821/1560-9561-2020-23-4-271-273 article EN Russian Pediatric Journal 2020-08-06

The article presents a case of successful surgical treatment the newborn with rare congenital pathology – thoracoschisis. had been transferred urgently 6 hours after birth from perinatal center. initial examination revealed chest defect measuring 6×3×3 cm in size and located along midclavicular line 4th to 6th ribs through which additional lobe liver prolapsed (Riedel’s lobe). After preoperative preparation, 17 birth, was carried out moving abdominal cavity, closing defects diaphragm thorax....

10.24110/0031-403x-2021-100-2-288-291 article EN PEDIATRIA Journal named after G N SPERANSKY 2021-03-28

Herlin-Werner-Vanderlich syndrome refers to the Müllerian duct anomalies, including uterine didelphys, obstructed hemivagina, and ipsilateral renal agenesis. At first stage of treatment, a reasonable intervention is opening hemivaginal septum by extra-vaginal access under visual control or using vaginoscopy. We identified rare variant defect identified, since longitudinal hemivagina did not prolapse through introinus, which required complex diagnosis surgical aid in newborn. A significant...

10.46563/1560-9561-2021-24-1-56-60 article EN Russian Pediatric Journal 2021-03-12

The analysis of the balance elastase (MMP-2, MMP-9) and TIMP-4 was performed in order to determine their involvement pathogenesis NEC. A progressive duration NEC with sepsis is accompanied by increased serum concentrations MMP-9, MMP-2 TIMP-4. Increases MMP-2>503 ng/ml, MMP-9>812 ng/ml TIMP-4>1404 can be regarded as statistically significant predictors fatal outcome proposed method for determination outcomes newborns characterized high sensitivity (94%) specificity (87%).

10.15406/jpnc.2021.11.00438 article EN cc-by-nc Journal of Pediatrics & Neonatal Care 2021-03-29

We present a case of complete extended tubular esophageal duplication in newborn without concomitant abnormal development. Esophageal is diagnosed based on the clinical picture, direct laryngoscopy, esophagography and contrastenhanced computed tomography. The was removed by thoracoscopy, isolation from pharynx performed via separate dissection neck.

10.30946/2219-4061-2018-8-2-84-88 article EN cc-by-nc-nd Russian Journal of Pediatric Surgery Anesthesia and Intensive Care 2018-10-10

The review presents up-to-date data on pathophysiology, principles of diagnosis, and surgical treatment chronic abdominal syndrome (CAS) with localization in the right iliac region (HASRIR) children. There are summarized histological changes proving relationship between appendix pathology localized pain sensitivity, specificity, information content laparoscopy diagnosis causes periodic were shown to reach 90.9%. Significant macroscopic signs CAS during as follows: adhesions involving...

10.18821/1560-9561-2020-23-3-198-203 article EN Russian Pediatric Journal 2020-07-03

The terminology of chronic abdominal pain, as well further treatment tactics, are still the subject debate. Conservative in some patients with pain is ineffective. Laparoscopic appendectomy a scientifically based surgical intervention for syndrome localization right iliac region children who do not show peritoneal signs and changes laboratory parameters, exception intercurrent pathology by non-invasive methods.

10.19163/1994-9480-2020-2(74)-178-181 article EN Journal of Volgograd State Medical University 2020-02-15

Rectal prolapse (RP) is one of the most expected complications following treatment anorectal malformations that occurs in 3.8% to 60% cases. The main method surgical RP anoplasty with a recurrence rate after surgery up 33%. authors describe indications, technique and results transanal rectal mucosectomy muscular plication (TRMMP) proposed by Dr. Luis De La Torre-Mondragon, MD, Pediatric Colorectal Surgeon Children's Hospital Colorado (CHCO), Aurora, Colorado, United States, for children...

10.24110/0031-403x-2022-101-6-51-57 article EN PEDIATRIA Journal named after G N SPERANSKY 2022-11-29

The article presents a case of successful surgical treatment 3-month-old child with rare pathology – tuberculosis lesion the intrathoracic lymph nodes causing compression left main bronchus. was admitted signs respiratory failure. An X-ray examination revealed emphysema lung. According to data contrast CT, volumetric hypodensive formation detected, which slightly accumulated contrast, capsule up 0,3 cm thick, located in area tracheal bifurcation, bronchus, esophagus, pulmonary bifurcation....

10.24110/0031-403x-2021-100-1-239-243 article EN PEDIATRIA Journal named after G N SPERANSKY 2021-01-24

The analysis of the balance elastase (MMP-2, MMP-9) and TIMP-4 was performed in order to determine its involvement pathogenesis NEC. A progressive duration NEC with sepsis is accompanied by increased serum concentrations MMP-9, MMP-2 TIMP-4. Increases MMP-2>503 ng/ml, MMP-9>812 ng/ml TIMP-4>1404 can be regarded as statistically significant predictors fatal outcome proposed method for determination outcomes newborns characterized high sensitivity (94%) specificity (87%).

10.35630/2199-885x/2021/11/1.17 article EN Archiv Euromedica 2021-03-27
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