A5023358043- Multiple Sclerosis Research Studies
- Health and Medical Research Impacts
- Brain Tumor Detection and Classification
- Health Systems, Economic Evaluations, Quality of Life
- Health and Medical Education
- Neurogenesis and neuroplasticity mechanisms
- Global Public Health Policies and Epidemiology
- Cardiac Imaging and Diagnostics
- Ethics and bioethics in healthcare
- Health and Lifestyle Studies
- Psychology of Moral and Emotional Judgment
- Cell Image Analysis Techniques
- Cancer Genomics and Diagnostics
- Pancreatic and Hepatic Oncology Research
- Alzheimer's disease research and treatments
- Cardiac pacing and defibrillation studies
- Olfactory and Sensory Function Studies
- Cancer, Hypoxia, and Metabolism
- Ethics in Clinical Research
- Cardiac electrophysiology and arrhythmias
- Advanced Neuroimaging Techniques and Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Dementia and Cognitive Impairment Research
- Women's cancer prevention and management
- Amyotrophic Lateral Sclerosis Research
Universidad de Santiago de Chile
2019-2023
Fundación Ciencia and Vida
2023
Universidad Bernardo O'Higgins
2023
Pontificia Universidad Católica de Chile
2017-2021
Ministerio de Salud
2019
Ministry of Health
2019
San Sebastián University
2018
Centre Hospitalier du Mans
2014-2015
Multiple Sclerosis patients' clinical symptoms do not correlate strongly with structural assessment done traditional magnetic resonance images. However, its diagnosis and evaluation of the disease's progression are based on a combination this imaging analysis complemented examination. Therefore, other biomarkers necessary to better understand disease. In paper, we capitalize machine learning techniques classify relapsing-remitting multiple sclerosis patients healthy volunteers techniques,...
Obesity is a global health problem. Its worldwide prevalence has tripled between 1975 and 2016, reaching in Chile of 34.4%, according to the National Health Survey 2016-2017. If this condition corresponds risk factor or primary disease widely discussed issue. It recognized as by American Medical Association World Organization, based on its metabolic hormonal features, such dysregulation appetite, abnormal energy balance endocrine dysfunction, among others. main environmental factors are...
Abstract Social cognition, including social perception, empathy and theory of mind, focuses on how people process, store, apply information about other situations, thus guiding interactions. Specific patterns have been described in patients affected by different pathologies, such as Alzheimer's disease, autism schizophrenia. Multiple sclerosis, an immune‐mediated neurodegenerative can affect global cognition 40–70% patients, with impact work family status. sclerosis shown a decrease...
The concept "Biobank" is relatively new in the scientific literature, and not yet consensually defined, even for World Health Organization (WHO). However, use of human samples biomedical research a very old activity. organized development Biobanks different places has grown last decade. experience countries continents been diverse. In this special article we intend to summarize, organize communicate national medical community, (i) Biobank, (ii) international map Research working Chile, (iii)...
Colorectal (CRC) is one of the most common types cancer worldwide. Most tumors develop from an adenoma in a period 10 to 15 years, but some may appear without previous adenomatous lesions. Seventy-five percent colorectal cancers are sporadic, 20% have family component (first or second-degree relatives with CRC) and 5% hereditary predisposition Mendelian pattern. The epidemiological evolution recent years Chile has worrisome treatment costs advanced stages burden for healthcare system. We...
The increase of the elderly population with a significant load non-communicable diseases, accelerates pathological aging and increases risk dementia, generating huge health, social economic cost for any country. Dementia does not have an effective treatment yet, therefore, focus must remain on prevention early diagnosis. stages dementia are known as mild cognitive impairment; at this stage is still possible to mitigate progression disease, however, health systems worldwide face difficulties...
Multiple sclerosis (MS), a neuroinflammatory and demyelinating disease, modifies the normal connectivity among different brain regions involved in specific functions. Functional magnetic resonance imaging (fMRI), based on local changes oxygen level as response to increase neural activity, provides an approach dynamics which give us overview visual, motor cognitive dysfunction their mechanisms.An advanced search was performed using PubMed. Terms 'fMRI', 'visual', 'motor', 'cognitive'...
Radiological biomarkers of cognitive impairment in Multiple Sclerosis (MS) are still scarce. This study aimed to identify subcortical white matter related verbal episodic memory MS patients and healthy controls using a Machine Learning approach.
ABSTRACT Background: Multiple sclerosis exhibits specific neuropathological phenomena driving to both global and regional brain atrophy. At the clinical level, disease is related functional decline in cognitive domains as working memory, processing speed, verbal fluency. However, compromise of social-cognitive abilities has concentrated some interest recent years despite available evidence suggesting risk disorganization social life. Recent studies have used MiniSEA test assess cognition...
With or without a COVID19 pandemic, cancer is and will continue to be one of the greatest health challenges on planet. In Chile, during 2016, this disease was second cause death in country 2019, it first seven Chilean regions, surpassing cardiovascular diseases. advent precision medicine as powerful tool for control, necessary have genomic, proteomic, molecular data general, ideally population scale. This essential decision-making, example public private oncology, cost-effective possible....
For more than a century the training of medical professionals has been organized according to Flexnerian model, which comprises three cycles: basic, clinical and clerkship. On other hand, accelerated development biomedical sciences modified competences first cycle. Additionally, new skills required for practice, such as teamwork innovation tool solve health problems, challenged in recent years classic paradigm education. Therefore, schools have developed multiple strategies deal with it,...
En el contexto de una población que envejece, cáncer representa las primeras causas muerte a nivel mundial, así como también, más importantes carga enfermedad. Diferentes entidades internacionales han provisto directrices los países en relación con la manera debieran organizar manejo este expansivo problema salud. Dichos lineamientos, sido sistematizados través llamados “planes nacionales para control del cáncer”, denominación ampliamente adoptada lo largo planeta. Desde actores relevantes,...
Radiological biomarkers of cognitive impairment in Multiple Sclerosis (MS) is still scarce. This study aimed to identify subcortical white matter related verbal episodic memory MS patients and healthy controls, by using a random forest approach.
Cancer constitutes the second most common cause of death worldwide and is expected to become leading one, even above cardiovascular diseases. The understanding cellular molecular basis cancer has led not only proper development chemotherapy but also target therapies. Although these advances are related with improved survival rates among patients, it poorly impacted its incidences. In this regard, lack knowledge regarding impact that several carcinogenic factors their interactions have on...