David O Sohutskay

ORCID: 0000-0002-1669-7784
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About
Contact & Profiles
Research Areas
  • Wound Healing and Treatments
  • Collagen: Extraction and Characterization
  • Cellular Mechanics and Interactions
  • Neurosurgical Procedures and Complications
  • Electrospun Nanofibers in Biomedical Applications
  • Cancer Cells and Metastasis
  • Breast Implant and Reconstruction
  • Breast Cancer Treatment Studies
  • Parkinson's Disease Mechanisms and Treatments
  • Dermatologic Treatments and Research
  • Atrial Fibrillation Management and Outcomes
  • 3D Printing in Biomedical Research
  • Testicular diseases and treatments
  • Vascular Malformations and Hemangiomas
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac Arrhythmias and Treatments
  • Intracranial Aneurysms: Treatment and Complications
  • Attention Deficit Hyperactivity Disorder
  • Cerebral Venous Sinus Thrombosis
  • Pituitary Gland Disorders and Treatments
  • Tendon Structure and Treatment
  • Multiple Myeloma Research and Treatments
  • Bone Tissue Engineering Materials
  • Schizophrenia research and treatment
  • Facial Nerve Paralysis Treatment and Research

Mayo Clinic in Arizona
2024-2025

Mayo Clinic
2024-2025

Indiana University – Purdue University Indianapolis
2020-2024

Indiana University School of Medicine
2020-2024

WinnMed
2024

Purdue University West Lafayette
2019-2023

Aim: To evaluate dermal regeneration scaffolds custom-fabricated from fibril-forming oligomeric collagen where the total content and spatial gradient of fibrils was specified. Materials & methods: Microstructural mechanical features were verified by electron microscopy tensile testing. The ability to induce rat full-thickness skin wounds determined compared with no fill control, autograft a commercial dressing. Results: Increasing fibril oligomer inhibited wound contraction decreased...

10.2217/rme-2019-0084 article EN Regenerative Medicine 2020-02-01

Mucuna pruriens, the velvet bean, is an herbal supplementsold at many online retailers or supermarkets.The raw plant contains roughly 5% levodopa by volume and commercial preparations typically contain 100 mg more of per capsule.Given this, it unsurprising that appropriate doses prurienssupplementation has in some studiesshown efficacy treatment Parkinson's disease (PD)comparable to pharmaceutical gradepreparations such as carbidopa/levodopa immediate release (IR) extended (ER) 1 .Dopamine...

10.14802/jmd.24067 article EN cc-by-nc Journal of Movement Disorders 2024-05-20

ABSTRACT Evidence describing the use of plerixafor in off‐label population relapsed/refractory germ cell tumors (GCT) is limited. We aim to describe effect rescue versus preemptive on apheresis collection days, yields, and cost. retrospectively collected data 77 consecutive patients (at least 15 years age) with GCT who underwent peripheral blood stem (PBSC) for autologous transplant between January 1, 2020 May 2022. Depending insurance approval, was given either as “rescue” (after a first...

10.1002/jca.22145 article EN cc-by-nc-nd Journal of Clinical Apheresis 2024-09-18

Breast cancer is the most commonly diagnosed type worldwide. Given high survivorship, increased focus has been placed on long-term treatment outcomes and patient quality of life. While breast-conserving surgery (BCS) preferred strategy for early-stage breast cancer, anticipated healing deformation (cosmetic) weigh heavily surgeon selection between BCS more aggressive mastectomy procedures. Unfortunately, surgical following are difficult to predict, owing complexity tissue repair process...

10.1101/2023.04.26.538467 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2023-04-28

OBJECTIVES/GOALS: Difficult-to-heal wounds of the skin are a common and costly medical problem. Dermal replacement strategies have emerged as solution, but challenge is identification optimal scaffold parameters. We present model for assessment clinical potential collagen scaffolds wound healing. METHODS/STUDY POPULATION: In previous animal experiments, we evaluated dermal custom-fabricated from fibril-forming oligomer with controlled fibril density (4, 20, 40mg/cm 3 ) spatial gradients in...

10.1017/cts.2020.58 article EN cc-by-nc-nd Journal of Clinical and Translational Science 2020-06-01
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