Ganesh M. Nawkar

ORCID: 0000-0002-1693-097X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Light effects on plants
  • Photosynthetic Processes and Mechanisms
  • Plant Molecular Biology Research
  • Endoplasmic Reticulum Stress and Disease
  • Heat shock proteins research
  • Redox biology and oxidative stress
  • Plant Stress Responses and Tolerance
  • Insect and Pesticide Research
  • Insect Resistance and Genetics
  • Autophagy in Disease and Therapy
  • Genetics, Aging, and Longevity in Model Organisms
  • Ubiquitin and proteasome pathways
  • Cell death mechanisms and regulation
  • CRISPR and Genetic Engineering
  • Genetics and Neurodevelopmental Disorders
  • Plant Genetic and Mutation Studies
  • RNA and protein synthesis mechanisms
  • Microbial Inactivation Methods
  • RNA Research and Splicing
  • Plant Gene Expression Analysis
  • Plant Reproductive Biology
  • RNA modifications and cancer

University of Lausanne
2023

Gyeongsang National University
2011-2021

Significance In nature, plants are inevitably exposed to adverse conditions such as salinity, drought, and extreme temperatures. Recent reports suggest that environmental stresses critically affect the protein-folding capacity of endoplasmic reticula (ER), leading ER stress. As growth development significantly depend on light environment, crosstalk between signaling stress response explained in current research can be a unique feature plants. Our results increases sensitivity ELONGATED...

10.1073/pnas.1609844114 article EN Proceedings of the National Academy of Sciences 2017-02-06

In Arabidopsis thaliana, CONSTANS (CO) plays an essential role in the regulation of photoperiodic flowering under long-day conditions. CO protein is stable only afternoon long days, when it induces expression FLOWERING LOCUS T (FT), which promotes flowering. The blue-light photoreceptor FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (FKF1) interacts with and stabilizes by unknown mechanism. Here, we provide genetic biochemical evidence that FKF1 inhibits CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1)-dependent...

10.1038/s41467-017-02476-2 article EN cc-by Nature Communications 2017-12-18

Phototropic bending of plants towards a light source allows them to position their photosynthetic tissues optimize capture. In light-grown (deetiolated) Arabidopsis seedlings, phototropic the hypocotyl is inhibited by with high red:far-red ratio (HRFR) and levels blue (HBL). This occurs via activation phytochrome B (phyB) cryptochrome 1 (cry1) photoreceptor signaling pathways. Both phyB cry1 act upstream PHYTOCHROME INTERACTING FACTOR (PIF) transcription factors, which are required for in...

10.1101/2025.04.09.647958 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-04-15

Summary Investigation of the endoplasmic reticulum‐associated degradation (ERAD) system in plants led to identification ERAD‐mediating RING finger protein (EMR) as a plant‐specific ERAD E3 ligase from Arabidopsis . EMR was significantly up‐regulated under reticulum (ER) stress conditions. The purified bacteria displayed high activity, and tobacco leaf‐produced mediated mildew resistance locus O‐12 (MLO12) proteasome‐dependent manner. Subcellular localization coimmunoprecipitation analyses...

10.1111/nph.15279 article EN New Phytologist 2018-06-22

The P3 proteins are plant-specific ribosomal P-proteins; however, their molecular functions have not been characterized. In a screen for components of heat-stable high-molecular weight (HMW) complexes, we isolated the protein AtP3B from heat-treated Arabidopsis suspension cultures. By size-exclusion chromatography (SEC), SDS-PAGE and native PAGE followed by immunoblotting with anti-AtP3B antibody, showed that was stably retained in HMW complexes following heat shock. level mRNA increased...

10.1111/pce.12742 article EN Plant Cell & Environment 2016-03-23

BAG (Bcl-2 athanogene) family proteins are conserved in a wide range of eukaryotes, and they have been proposed to play crucial role plant programmed cell death (PCD). During the past decade, with help advanced bioinformatics tools, seven homologs genes identified Arabidopsis genome; these involved pathogen attack abiotic stress conditions. In this study, gene expression members under environmental stresses was analyzed using Botany Array Resource (BAR) browser tool silico data were...

10.1007/s00709-016-0961-3 article EN cc-by PROTOPLASMA 2016-03-22

In plants, light direction is perceived by the phototropin photoreceptors, which trigger directional growth responses known as phototropism. The formation of a activation gradient across photosensitive organ initiates this response. However, optical tissue properties that functionally contribute to phototropism remain unclear. work, we show intercellular air channels limit transmittance through various organs in several species. Air enhance scattering Arabidopsis hypocotyls, thereby...

10.1126/science.adh9384 article EN Science 2023-11-23

A novel Arabidopsis thaliana inhibitor of apoptosis was identified by sequence homology to other known (IAP) proteins. IAP-like protein (AtILP) contained a C-terminal RING finger domain but lacked baculovirus IAP repeat (BIR) domain, which is essential for anti-apoptotic activity in family members. The expression AtILP HeLa cells conferred resistance against tumor necrosis factor (TNF)-α/ActD-induced through the inactivation caspase activity. In contrast AtILP, did not inhibit caspase-3,...

10.1074/jbc.m111.262204 article EN cc-by Journal of Biological Chemistry 2011-09-17

Interaction between light signaling and stress response has been recently reported in plants. Here, we investigated the role of CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), a key regulator signaling, endoplasmic reticulum (ER) Arabidopsis. The cop1-4 mutant Arabidopsis plants were highly sensitive to ER induced by treatment with tunicarmycin (Tm). Interestingly, abundance nuclear-localized COP1 increased under conditions. Complementation wild-type or variant types revealed that nuclear...

10.3390/ijms221910772 article EN International Journal of Molecular Sciences 2021-10-05

Summary In light-limiting conditions, aerial organs of most plants reorient their growth towards the light to improve photosynthesis, through a process known as phototropism 1-3 . The blue receptors phototropin control phototropic responses light-induced protein kinase activity 4 Current models posit that asymmetric activation these sensory across unilaterally illuminated organ leads distribution hormone auxin ultimately leading re-orientation 4,5 However, tissue properties required generate...

10.1101/2023.02.22.529488 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-02-22
Coming Soon ...