A5037558313- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Blind Source Separation Techniques
- Vestibular and auditory disorders
- Visual perception and processing mechanisms
- Advanced MRI Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Neurological disorders and treatments
- Speech and Audio Processing
- Neural and Behavioral Psychology Studies
- Face Recognition and Perception
- Parkinson's Disease Mechanisms and Treatments
- Muscle activation and electromyography studies
- Neuroscience and Music Perception
- Hearing Loss and Rehabilitation
- Action Observation and Synchronization
- Atomic and Subatomic Physics Research
- Advanced MEMS and NEMS Technologies
- Gaze Tracking and Assistive Technology
- Photoreceptor and optogenetics research
- Direction-of-Arrival Estimation Techniques
- Cognitive Science and Education Research
- Neuroscience and Neural Engineering
- Epilepsy research and treatment
Aarhus University
2017-2024
University of Konstanz
2011-2023
Command Hospital Air Force
2012-2020
Texas Tech University
2019
Université Claude Bernard Lyon 1
2009-2013
Centre de Recherche en Neurosciences de Lyon
2011-2013
Inserm
2007-2013
Centre National de la Recherche Scientifique
2011-2013
Gènes, synapses et cognition
2013
Centre d'Exploration et de Recherche Médicale par Emission de Positons
2011
We observed robust coupling between the high- and low-frequency bands of ongoing electrical activity in human brain. In particular, phase theta (4 to 8 hertz) rhythm modulates power high gamma (80 150 band electrocorticogram, with stronger modulation occurring at higher amplitudes. Furthermore, different behavioral tasks evoke distinct patterns theta/high across cortex. The results indicate that transient low- high-frequency brain rhythms coordinates distributed cortical areas, providing a...
The spatial distribution of functional connectivity between brain areas and the disturbance introduced by focal lesions are poorly understood. Based on rationale that damaged tissue is disconnected from physiological interactions among healthy areas, this study aimed to map functionality according their with other areas.Magnetoencephalography recordings spontaneous cortical activity during resting state were obtained 15 consecutive patients 14 control subjects. Neural in was estimated using...
Many tomographic source localization algorithms used in biomagnetic imaging assume, explicitly or sometimes implicitly, that the activity at different brain locations are either independent correlation structure between sources is known. Among these a class of adaptive spatial filters known as beamformers, which have superior spatiotemporal resolution abilities. The performance beamformers robust to weakly coherent sources. However, extremely sensitive presence strongly A frequent mode...
We recorded the electrocorticogram directly from exposed cortical surface of awake neurosurgical patients during presentation auditory syllable stimuli. All were unanesthetized as part a language-mapping procedure for subsequent left-hemisphere tumor resection. Time-frequency analyses showed significant high-gamma (gammahigh: 70-160 Hz) responses left superior temporal gyrus, but no reliable response inferior frontal gyrus. Alpha suppression (alpha: 7-14 and event-related potential exhibited...
Significance To survive, organisms must constantly form predictions of the future based on past regularities. When are violated, action may be needed. Different scales environmental regularity need to encompass both subsecond repetitions and complex structures spanning longer timescales. How different parts brain monitor these temporal regularities produce prediction error signals is unclear. Utilizing subdural electrocorticographic electrodes with an auditory paradigm involving local global...
While functional imaging studies allow for a precise spatial characterization of resting state networks, their neural correlates and thereby fine-scale temporal dynamics remain elusive. A full understanding the mechanisms at play requires input from electrophysiological studies. Here, we discuss human non-human primate data that explore default-mode network. Beyond promising findings obtained with non-invasive approaches, emerging evidence suggests invasive recordings in humans will be...
NUTMEG is a source analysis toolbox geared towards cognitive neuroscience researchers using MEG and EEG, including intracranial recordings. Evoked unaveraged data can be imported to the for in either time or time-frequency domains. offers several variants of adaptive beamformers, probabilistic reconstruction algorithms, as well minimum-norm techniques generate functional maps spatiotemporal neural activity. Lead fields calculated from single overlapping sphere head models other software....
Beamforming is a popular method for functional source reconstruction using magnetoencephalography (MEG) and electroencephalography (EEG) data. Beamformers, which were first proposed MEG more than two decades ago, have since been applied in hundreds of studies, demonstrating that they are versatile robust tool neuroscience. However, certain characteristics beamformers remain somewhat elusive there currently does not exist unified documentation the mathematical underpinnings computational...
The specificity of neural responses to visual objects is a major topic in neuroscience. In humans, functional magnetic resonance imaging (fMRI) studies have identified several regions the occipital and temporal lobe that appear specific faces, letter-strings, scenes, or tools. Direct electrophysiological recordings cortical areas epileptic patients largely confirmed this modular organization, using either single-neuron peri-stimulus time-histogram intracerebral event-related potentials...
An object that differs markedly from its surrounding—for example, a red cherry among green leaves—seems to pop out effortlessly in our visual experience. The rapid detection of salient targets, independently the number other items scene, is thought be mediated by efficient search brain mechanisms. It not clear, however, whether actually an “effortless” bottom-up process or it also involves regions prefrontal cortex generally associated with top-down sustained attention. We addressed this...
Although bicycling and walking involve similar complex coordinated movements, surprisingly Parkinson's patients with freezing of gait typically remain able to bicycle despite severe difficulties in walking. This observation suggests functional differences the motor networks subserving However, a direct comparison brain activity related has never been performed, neither healthy participants nor patients. Such could potentially help elucidating cortical involvement control mechanisms through...
Inaccuracy of EEG electrode coordinates forms an error term in forward model generation and ultimate source reconstruction performance. This arises from the combination both intrinsic measurement noise digitization apparatus manual coregistration when selecting corresponding points on anatomical MRI volumes. A common assumption is that such would lead only to displacement localized sources. Here, we measured positions a 3D-printed full-scale replica head, using three different techniques:...
Beamformers are applied for estimating spatiotemporal characteristics of neuronal sources underlying measured MEG/EEG signals. Several MEG analysis toolboxes include an implementation a linearly constrained minimum-variance (LCMV) beamformer. However, differences in implementations and their results complicate the selection application beamformers may hinder wider adoption research clinical use. Additionally, combinations different sensor types (such as magnetometers planar gradiometers)...