A5006118614- Microbial metabolism and enzyme function
- Biochemical Acid Research Studies
- Organ Donation and Transplantation
- Bacteriophages and microbial interactions
- Organ Transplantation Techniques and Outcomes
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
- Microbial infections and disease research
- Renal Transplantation Outcomes and Treatments
- Pancreatitis Pathology and Treatment
- Antioxidant Activity and Oxidative Stress
- Antibiotic Resistance in Bacteria
- Periodontal Regeneration and Treatments
- Gut microbiota and health
- Renal Diseases and Glomerulopathies
- Gout, Hyperuricemia, Uric Acid
- Phagocytosis and Immune Regulation
- Adipokines, Inflammation, and Metabolic Diseases
- Eicosanoids and Hypertension Pharmacology
- Sphingolipid Metabolism and Signaling
- Glutathione Transferases and Polymorphisms
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Urological Disorders and Treatments
- Body Contouring and Surgery
Pomeranian Medical University
2017-2025
University of Szczecin
2018-2025
Malignant tumors are the second most common cause of death worldwide. More attention is being paid to link between body’s impaired oxidoreductive balance and cancer incidence. Much polyphenols derived from plants, as one their properties an antioxidant character: ability eliminate reactive oxygen nitrogen species, chelate specific metal ions, modulate signaling pathways affecting inflammation, raise level activity enzymes while lowering those with oxidative effects. The following three...
Problematic Internet Use is defined as a use of the which leads to various difficulties. The aim this study was check whether associated with health risks, such as: anti-health behaviors, depressive symptoms, abnormal body weight or eating disorders.This cross-sectional included 540 medical school students Polish descent (83.5% females; 16.5% males), whose mean age 22.49 years (SD = 5.20). participants were asked complete questionnaire set, including Test, Juczyński's Health-Related Behavior...
Chronic kidney disease (CKD) leads to irreversible changes in function and structure, with over 90% of patients developing arterial hypertension (HT). Renalase, dopamine, norepinephrine are believed influence HT development CKD progression. This study aims measure renalase, levels evaluate their potential as markers for progression, development, cardiovascular event risk. The involved 117 divided into four groups: 32 hemodialysis (before after treatment), 31 peritoneal dialysis patients, 24...
Alternative therapies against multidrug-resistant bacteria are widely investigated in the postantibiotic era. Polymicrobial biofilms formed by two or more species of fungi pose an additional threat. The removal such complex communities requires effort and a multidirectional approach. In this study, effectiveness bacteriophages vB_SauM-A (A) vB_SauM-D (D) combined with ciprofloxacin was used to combat Staphylococcus aureus presence Candida albicans both liquid culture biofilm. results showed...
Abstract Introduction Antioxidant enzymes protect the human body against harmful effects of oxidative stress. The activity antioxidant changes with age and depends on dietary nutrients such as fats vitamins, which can have a significant impact minimizing or exacerbating Aim To examine effect age, BMI, diet, physical activity, smoking status erythrocyte catalase, glutathione reductase, peroxidase S-transferase, superoxide dismutase, concentrations in healthy women. Material methods This study...
The aim of our study was to evaluate the influence asymptomatic infection and occurrence symptomatic COVID-19 on specific biochemical, renal, immune parameters-renalase, neutrophil gelatinase-associated lipocalin (NGAL) cystatin C (CysC), creatinine-and their weekly fluctuations during a one-month observation period in patients admitted hospital. involved 86 individuals: 30 with diagnosed COVID-19, 28 people confirmed IgG antibodies-the IG(+) group-and individuals without any (IgG, IgE)...
Chronic kidney disease (CKD) is an inflammatory leading to insufficiency and uremia. Renalase a novel flavoprotein with enzymatic activities. Previous studies have shown that chronic may influence renalase serum levels. metabolises catecholamines therefore be involved in the pathogenesis of hypertension other diseases circulatory system. In this study, we examined levels serum, erythrocytes urine from haemodialysis CKD patients. The study enrolled 77 patients 30 healthy subjects normal...
The liver has a huge impact on the functioning of our body and preservation homeostasis. It is exposed to many serious diseases, which may lead chronic failure this organ, becoming global health problem today. Currently, final form treatment in patients with end-stage (acute chronic) organ transplantation. proper function transplanted organs depends cellular processes immune individual factors. An enormous role process acceptance or rejection attributed to, among others, activation...
Platelets are actively involved in tissue injury site regeneration by producing a wide spectrum of platelet-derived growth factors such as PDGF (platelet-derived factor), IGF-1 (insulin-like TGF-β1 (transforming factor β), FGF (fibroblast etc. A rotating magnetic field (RMF) can regulate biological functions, including reduction or induction regarding inflammatory processes, cell differentiation, and gene expression, to determine the effect an RMF on regenerative potential platelets. The...
Oxidative stress is characterized by an excessive concentration of reactive oxygen species (ROS) resulting from a disturbance in the balance between ROS production and their removal antioxidant systems (SOD, CAT, GPx). Prolonged intense oxidative can cause various forms damage to cells, which markers are total capacity (TAC), modulator (ROMO1), malondialdehyde (MDA). It has been demonstrated that magnetic fields positively affect human health, for example, reducing stress. Determination...
INTRODUCTION Glomerulonephritis (GN) is a complex disease that affects the function of whole nephron. There are few data on serum levels most common biomarkers kidney and injury in GN, or studies provide ambiguous results. OBJECTIVES The aim study was to evaluate known kidney-specific nonspecific markers renal patients with diagnosed primary secondary without presence nephrotic syndrome (NS) arterial hypertension (AH). PATIENTS AND METHODS included 58 GN 6 congenital defects (CD) AH (CD+AH)....
INTRODUCTIONRenalase is a novel flavin adenine dinucleotide-dependent amine oxidase with catecholamine-degrading activity.The kidneys are the main source of this enzyme.OBJECTIVES In study, we examined concentrations renalase in serum, urine, and erythrocytes patients chronic kidney disease (CKD). PATIENTS AND METHODSWe enrolled 155 white CKD 30 healthy controls.Renalase were measured using an enzyme -linked immunosorbent assay.RESULTS Serum levels higher than controls: median (Q1-Q3), 103...
The purpose of this study was to analyze the strategies and styles coping with stress self-esteem in patients diagnosed prostate cancer. One hundred five cancer participated study. Coping were assessed Mini-Cope questionnaire, Inventory for Stressful Situations, Rosenberg Self-Esteem Scale. Patients’ analyzed using a Pearson correlation analysis. A stepwise linear regression analysis performed determine predictors self-esteem. level positively related task-focused style (r = 0.228)...
Phage-antibiotic combination-based protocols are presently under heightened investigation. This paradigm extends to engagements with bacterial biofilms, necessitating novel computational approaches comprehensively characterize and optimize the outcomes achievable via these combinations. study aimed explore Response Surface Methodology (RSM) in optimizing antibiofilm activity of bacteriophage-antibiotic We employ a combination antibiotics (gentamicin, meropenem, amikacin, ceftazidime,...
Abstract Background Platelet activation is an important side effect of dialysis, resulted in a subsequent release arachidonic acid (AA) from activated platelets. AA involved many pathologic conditions, such as inflammation, asthma, cancer, diabetes, hypertension, and the pathogenesis kidney disease. The aim this study was to define whether dialysis type affects concentration derivatives patients with chronic Methods 117 were qualified group. Based on renal replacement therapy, divided into...
Renalase is an enzyme and a cytokine involved in cell survival. Since its discovery, associations between it both cardiovascular kidney disease have been noted. Recognizing this, we conducted study which followed patients with chronic disease.
Xanthine oxidoreductase (XOR) is a hydroxylase enzyme involved in the metabolism of purines. XOR activity can vary: homodimer protein be converted into two different isoforms XD (antioxidant) and XO (prooxidant). Oxidative stress inflammation that accompanying chronic kidney disease (CKD), dialysis, transplantation, resulted platelet activation. Present study aimed to determine influence applied renal replacement therapy on xanthine its activity.The group consisted 117 patients, divided 4...
Platelets are the first to reach site of tissue damage and secrete substances like platelet growth factors (GFs), which perform many different functions in human body. Many studies suggest that GFs such as transforming GF (TGF), platelet‐derived (PDGF), or insulin‐like GF‐1 (IGF‐1) may be markers survival, disease severity, post‐coronavirus (COVID) complications. The study aimed analyze concentration TGF‐ β , IGF‐1, PDGF‐BB COVID‐19 patients compared control group (GK). consisted 50 (23 men...