- Physical Activity and Health
- Dementia and Cognitive Impairment Research
- Mobile Health and mHealth Applications
- Cerebral Palsy and Movement Disorders
- Technology Use by Older Adults
- Stroke Rehabilitation and Recovery
- Nutritional Studies and Diet
- Health and Medical Studies
- Nutrition and Health in Aging
- COVID-19 and Mental Health
- Health disparities and outcomes
- Balance, Gait, and Falls Prevention
- Frailty in Older Adults
- Context-Aware Activity Recognition Systems
- Social and Behavioral Studies
- Telemedicine and Telehealth Implementation
- Health and Well-being Studies
- Behavioral Health and Interventions
- Ion channel regulation and function
- Emergency and Acute Care Studies
- Social and Demographic Issues in Germany
- Healthcare cost, quality, practices
- Spinal Fractures and Fixation Techniques
- Social Policies and Healthcare Reform
- Sepsis Diagnosis and Treatment
Karlsruhe Institute of Technology
2017-2024
German National Bone Marrow Donor Registry
2023
Klinikum Fulda
2014
Klinikum Kassel
2009
Little is known about the association between physical activity (PA) and cognitive trajectories in older adults.
The increasing prevalence of dementia in the next decades is accompanied by various societal and economic problems. Previous studies have suggested that physical activity positively affects motor cognitive skills individuals with (IWD). However, there insufficient evidence probably related to several methodological limitations. Moreover, date adequate interventions specifically developed for IWD are lacking.
Recommendations for assessing motor performance in individuals with dementia (IWD) are rare, and most existing assessment tools previously applied IWD were initially developed healthy older adults. However, their counterparts differ cognitive capabilities, which needs to be considered when designing studies this population. This article aims give recommendations assessments promote standardisation based on a structured discussion of identified used previous trials.Appropriateness intensively...
Abstract Background There is a high prevalence of gait impairments in individuals with dementia (IWD). Gait are associated increased risk falls, disability, and economic burden for health care systems. Only few studies have investigated the effectiveness physical activity on performance IWD, reporting promising but inconsistent results. Thus, this study aimed to investigate multimodal exercise program (MEP) IWD. Methods In parallel-group randomized controlled trial, we enrolled 319 IWD mild...
Dementia affects physical as well cognitive performance. In individuals with dementia (IWD), decline in performance increases disease progression and is associated higher functional dependence decreased quality of life. It paramount to examine factors that potentially preserve IWD, particularly light conflicting findings on the effectiveness activity interventions mainly due limited number high-quality studies, large heterogeneity methods used, or insufficient reporting methods. The aim this...
In this study derived from the population-based Mayo Clinic Study of Aging, we investigated whether non-exercise physical activity (PA) was associated with global and domain-specific cognitive trajectories (memory, language, visuospatial skills, attention) association differed by apolipoprotein E (APOE) ε4 genotype status. We included 2061 community-dwelling individuals aged ≥ 70 years (50.5% males, 26.7% APOE carriers) who were cognitively unimpaired at baseline on whom serial data...
Abstract We aimed to examine the effects of a 16-week multimodal exercise program (MEP) on activities daily living (ADL) in individuals with dementia (IWD). Furthermore, we investigated participants’ individual response MEP and whether baseline cognitive motor performance explain ADL performance. conducted multicenter randomized controlled trial (RCT) involving 319 participants aged ≥ 65 years mild moderate dementia. were assessed at after intervention using Barthel Index (BI), Erlangen Test...
Abstract The present study examined the longitudinal association and interaction between lack of engaging in physical activity (PA) presence neuropsychiatric symptoms (NPS) with risk incident mild cognitive impairment (MCI). authors conducted a prospective cohort setting population-based Mayo Clinic Study Aging Minnesota, USA, involving 3083 cognitively unimpaired persons aged ≥ 50 years (1570 males; median age, 74 years). Predictors included: light, moderate, vigorous intensity PA within 1...
This study examined associations between physical activity (PA) and neuropsychiatric symptoms (NPS) in older adults free of dementia.This cross-sectional included 3,222 individuals ≥70 years age (1,655 men; mean±SD age=79.2±5.6; cognitively unimpaired, N=2,723; mild cognitive impairment, N=499) from the population-based Mayo Clinic Study Aging. PA (taken as a presumed predictor) midlife (i.e., when participants were 50-65 age) late life year prior to assessment) was assessed with...
The promotion of physical activity in individuals with dementia living nursing homes is crucial for preserving and cognitive functions the associated quality life. Nevertheless, implementation programs this setting challenging, as time expertise home staff are limited. This situation was further exacerbated by COVID-19 pandemic. Mobile health apps may be a sustainable approach to overcome these challenges long term. Therefore, Individualized Cognitive Physical Exercise-App (the InCoPE-App)...
Physical activity interventions can alleviate the course of disease for individuals with dementia (IWD) who have been extraordinarily affected by COVID-19 pandemic. Information and Communication Technology (ICT) provides new opportunities not only to mitigate negative effects pandemic but also sustainably improve everyday life IWD in nursing homes. The aim present study was evaluate ICT-based InCoPE-App, which used assess physical cognitive performance deliver individualized exercise IWD,...
The COVID-19 pandemic has had drastic consequences on everyday life in nursing homes. Limited personnel resources and modified hygiene safety measures (eg, no external exercise instructors, group settings) have often led to interrupted physical treatments. As a consequence, people with dementia benefiting from individualized programs are affected by the pandemic's impact.Our goal is develop an easily applicable mobile application (Individualized Cognitive Physical Exercise [InCoPE] app)...
<sec> <title>BACKGROUND</title> The Covid-19 pandemic has drastic consequences on everyday life in nursing homes. Limited personal resources and high hygiene standards often lead to interrupting physical exercise treatment. As a consequence, individuals with dementia (IWD) profiting from individualized programs, are affected by the pandemic’s impact. </sec> <title>OBJECTIVE</title> Our goal is develop an easily applicable application allowing home employees (NHE) test cognitive function...
Isolierte Verletzungen der zervikalen Halswirbelsäule sind ein seltener Grund für Einsätze im Rettungsdienst. Es wird über den Fall einer schweren Halswirbelsäulenverletzung mit unerwartetem Ausgang berichtet.
<sec> <title>BACKGROUND</title> The promotion of physical activity in individuals with dementia living nursing homes is crucial for preserving and cognitive functions the associated quality life. Nevertheless, implementation programs this setting challenging, as time expertise home staff are limited. This situation was further exacerbated by COVID-19 pandemic. Mobile health apps may be a sustainable approach to overcome these challenges long term. Therefore, Individualized Cognitive Physical...
Physical activity (PA) can have a beneficial effect on cognitive and physical performance in individuals with dementia (IWD), including those residing nursing homes. However, PA interventions homes are usually delivered using group setting, which may limit the effectiveness of intervention due to heterogenous nature IWD. Therefore, purpose this study was identify clusters based values, could be used improve individualization interventions.Based variables 230 IWD, cluster analysis conducted....
PURPOSE: To investigate whether physical exercise (PE) is differentially associated with global and domain-specific cognitive trajectories (memory, language, visuospatial skills, attention) among Apolipoprotein E (APOE) ε4 carriers non-carriers. METHODS: We included 2,060 community-dwelling individuals aged 70 years older (50.5% males, 26.6% APOE carriers). Participants were cognitively unimpaired at baseline, underwent serial testing self-reported assessment of PE engagement in midlife...