A5038974164- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Biomedical Ethics and Regulation
- Nanoplatforms for cancer theranostics
- Pluripotent Stem Cells Research
- Hydrogels: synthesis, properties, applications
- graph theory and CDMA systems
- Graphene and Nanomaterials Applications
- Reconstructive Facial Surgery Techniques
- Cancer Cells and Metastasis
- Facial Rejuvenation and Surgery Techniques
- Body Contouring and Surgery
- Mesenchymal stem cell research
- Nitric Oxide and Endothelin Effects
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Renal and related cancers
- Intracranial Aneurysms: Treatment and Complications
- Phagocytosis and Immune Regulation
- CRISPR and Genetic Engineering
- Extracellular vesicles in disease
- Mathematical Control Systems and Analysis
- Cybersecurity and Information Systems
Shanghai Ninth People's Hospital
2020-2024
Shanghai Jiao Tong University
2020-2024
Abstract Macrophage immunotherapy is an emerging treatment strategy that modulates the immune system to promote wound healing. The functionality and regeneration of tissue depend on spatially temporally regulating biophysical biochemical microenvironmental with poorly understood mechanisms. Biomaterials are carefully crafted display deliver macrophage regulatory signals in a precise near‐physiological way, serving as powerful artificial microenvironments which explore direct fate...
Abstract Exudate management is critical to improve chronic wound healing. Herein, inspired by a Janus‐structured lotus leaf with asymmetric wettability, Janus electrospun short fiber scaffold fabricated via electrospinning technologies and modeling. This composed of hydrophilic 2D curcumin‐loaded hydrophobic 3D layer‐by‐layer assembly electrostatic interactions which can aggregate the exudate pumping from layer multiple contact points between fibers, simultaneously trigger cascade release...
Conditioned medium (CM) contains variety of factors secreted by cells, which directly regulate cellular processes, showing tremendous potential in regenerative medicine. Here, for the first time, we proposed a novel therapy mediated biodegradable micro-nano electrospun fibers loaded with highly active conditioned adipose-derived stem cells (ADSC-CM). ADSC-CM was successfully into nanofibers biological protection and controllable sustained-release properties emulsion electrospinning protein...
The traditional membrane with single structure cannot satisfy complex clinical applications. Inspired by lotus leaf, a novel Janus has achieved more attention recently. is which two faces opposite properties. This special endows it asymmetric surface wettability, can provide an intrinsic driving force to transport along specified direction, thus achieve unidirectional liquid and selective separation. promising future, been widely used in chemical fields such as self-cleaning, oil/water...
Arterial vasospasm after microsurgery can cause severe obstruction of blood flow manifested as low tissue temperature, leading to necrosis. The timely discovery and synchronized treatment become pivotal. In this study, a reversible, intelligent, responsive thermosensitive hydrogel system is constructed employing both the gel–sol transition sol–gel transition. "reversible (RTS)" loaded with verapamil hydrochloride designed dynamically continuously regulate extravascular microenvironment by...
Over the past few decades, biomaterials have made rapid advances in tissue engineering. In particular, there been several studies on vascularization during skin flap regeneration for plastic surgery. From perspective of function, used to improve flaps are primarily classified into two types: (1) electrospun nanofibrous membranes as porous scaffolds, and (2) hydrogels cell or cytokine carriers. Based their source, various natural, synthetic, semi-synthetic developed with respective...
The frontispiece image depicts how stem cells develop from a single cell into different types of organoids. It represents the content review "Stem for organoids". In this review, culture process and various applications derived organoids were summarized, proposed insightful thoughts engineering in view current shortcomings summarized to achieve further application clinical translation engineered organoid research.
BACKGROUND Facial fold and groove formation is influenced by the ptosis of superficial fat compartments in mid-face region. OBJECTIVE This study aimed to design a facial rejuvenation technique that targets sagging achieves youthful configuration. MATERIALS AND METHODS A total 102 patients underwent suture net restoration. Each specific compartment was carefully lifted held at regional ligaments effectively restore volume distribution. Patient outcomes were evaluated through preoperative...