A5077385818- Marine Ecology and Invasive Species
- Planarian Biology and Electrostimulation
- Marine Biology and Environmental Chemistry
- Developmental Biology and Gene Regulation
- Animal Genetics and Reproduction
- Classical Antiquity Studies
- Genetics, Aging, and Longevity in Model Organisms
- Cephalopods and Marine Biology
- Marine Biology and Ecology Research
- Fish Biology and Ecology Studies
- Insect and Arachnid Ecology and Behavior
- Historical, Religious, and Philosophical Studies
- Congenital limb and hand anomalies
- Marine and coastal plant biology
- Fish Ecology and Management Studies
- Marine and environmental studies
- Genetics, Bioinformatics, and Biomedical Research
- Environmental DNA in Biodiversity Studies
- Nicotinic Acetylcholine Receptors Study
- Protist diversity and phylogeny
- Single-cell and spatial transcriptomics
- Religion, Ecology, and Ethics
- Marine Invertebrate Physiology and Ecology
- Congenital heart defects research
- Technology Assessment and Management
Marine Biological Laboratory
2017-2025
Washington University in St. Louis
2023-2025
Institut Jacques Monod
2016-2024
Centre National de la Recherche Scientifique
2024
Université Paris Cité
2016-2024
University of Maryland, College Park
2015-2016
Sorbonne Université
2016
Sorbonne Paris Cité
2016
Tulane University
2010-2012
Louisiana State University Health Sciences Center New Orleans
2007
Abstract Development of sexual characters and generation gametes are tightly coupled with growth. Platynereis dumerilii is a marine annelid that has been used to study germline development gametogenesis. P. germ cell clusters found across the body in juvenile worms, eventually form gametes. Like other segmented grows by adding new segments at its posterior end. The number reflect growth state worms therefore useful measurable metric growth‐reproduction crosstalk. To understand how correlates...
Many annelids can regenerate missing body parts or reproduce asexually, generating all cell types in adult stages. However, the putative stem populations involved these processes, and diversity of generated by them, are still unknown. To address this, we recover 75,218 single transcriptomes highly regenerative asexually-reproducing annelid Pristina leidyi. Our results uncover a rich type including specific as well novel types. Moreover, characterise transcription factors gene networks that...
Cell lineage, cell cycle, and fate are tightly associated in developmental processes, but vivo studies at single-cell resolution showing the intricacies of these associations rare due to technical limitations. In this study on marine annelid Platynereis dumerilii, we investigated lineage 4d micromere, using high-resolution long-term live imaging complemented with a live-cell cycle reporter. is origin mesodermal lineages germline many spiralians. We traced within demonstrate that embryonic...
Abstract Annelids are a broadly distributed, highly diverse, economically and environmentally important group of animals. Most species can regenerate missing body parts, many able to reproduce asexually. Therefore, annelids generate all adult cell types in stages. However, the putative stem populations involved these processes, as well diversity generated by them, still unknown. Here, we recover 75,218 single transcriptomes Pristina leidyi , regenerative asexually-reproducing freshwater...
Gonads are specialized gamete-producing structures that, despite their functional importance, generated by diverse mechanisms across groups of animals and can be among the most plastic organs body. Annelids, segmented worms, a group in which gonads have been documented to able regenerate, but little is known about what factors influence gonad development or how these regenerate. In this study, we aimed identify that presence size investigate regeneration small asexually reproducing annelid,...
The marine annelid
Gametogenesis is the process by which germ cells differentiate into mature sperm and oocytes, essential for sexual reproduction. The sex-specific molecular programs that drive spermatogenesis oogenesis can also serve as sex identification markers. Platynereis dumerilii a research organism has been studied in many areas of developmental biology. However, investigations often disregard sex, P. juveniles lack dimorphism. mechanisms gametogenesis segmented worm are largely unknown. In this...
The imperial cone uses small-molecule mimicry, imitating the pheromones of its worm prey in a hunting strategy.
Platynereis dumerilii is a marine segmented worm (annelid) with externally fertilized embryos and it can be cultured for the full life cycle in laboratory. The accessibility of larvae combined breadth established molecular functional techniques has made P. an attractive model studying development, cell lineages, type evolution, reproduction, regeneration, nervous system, behavior. Traditionally, these worms have been kept rooms dedicated their culture. This allows regulation temperature...
Gametogenesis is the process by which germ cells differentiate into mature sperm and oocytes, essential for sexual reproduction. The sex-specific molecular programs that drive spermatogenesis oogenesis can also serve as sex identification markers. Platynereis dumerilii a research organism has been studied in many areas of developmental biology. However investigations often disregard sex, P. juveniles lack dimorphism. mechanisms gametogenesis segmented worm are largely unknown. In this study,...
Abstract Many animals rely on sexual reproduction to propagate by using gametes (oocytes and sperm). Development of characters generation are tightly coupled with the growth an organism. Platynereis dumerilii is a marine segmented worm which has been used study germline development gametogenesis. 4 Primordial Germ Cells (PGCs) that arise early in these cells thought give rise germ cell clusters found across body juvenile worms. The eventually form gametes. stages how PGCs become numerous not...
ABSTRACT Regeneration, regrowing lost and injured body parts, is an ability that generally declines with age or developmental transitions (i.e. metamorphosis, sexual maturation) in many organisms. Regeneration also energetically a costly process, trade-offs occur between regeneration other processes such as somatic growth, reproduction. Here we investigate the interplay of regeneration, reproduction, segmented worm Platynereis dumerilii . P. can regenerate its whole posterior axis, along...
Abstract Regeneration of missing body parts can be observed in diverse animal phyla, but it remains unclear to which extent these capacities rely on shared or divergent principles. Research into this question requires detailed knowledge about the involved molecular and cellular principles suitable reference models. By combining single-cell RNA sequencing mosaic transgenesis marine annelid Platynereis dumerilii , we map profiles lineage restrictions during posterior regeneration. Our data...