- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Landslides and related hazards
- Rock Mechanics and Modeling
- Geotechnical Engineering and Analysis
- Geotechnical Engineering and Underground Structures
- Soil and Unsaturated Flow
- Civil and Geotechnical Engineering Research
- Climate change and permafrost
- Pneumonia and Respiratory Infections
- Drilling and Well Engineering
- Actinomycetales infections and treatment
- Cancer-related molecular mechanisms research
- Geotechnical and Geomechanical Engineering
- Lung Cancer Diagnosis and Treatment
- Geotechnical Engineering and Soil Stabilization
- Tunneling and Rock Mechanics
- Plant-based Medicinal Research
- Regional Development and Environment
- Tracheal and airway disorders
- High-Velocity Impact and Material Behavior
- Vibration and Dynamic Analysis
- Underground infrastructure and sustainability
- RNA modifications and cancer
- Macrophage Migration Inhibitory Factor
Tongji University
2010-2023
Shanghai Clinical Research Center
2022-2023
Shanghai Pulmonary Hospital
2018-2023
Hebei University of Technology
2022
Hebei Petroleum University of Technology
2022
Infectious diseases caused by nontuberculous mycobacteria (NTM) are increasingly common. This retrospective cohort study examined factors associated with outcomes in patients from Shanghai who had NTM pulmonary disease (NTMPD) January 2014 to December 2018. The causative bacterial species, drug susceptibility test results, treatment outcomes, sputum culture conversion rate, and risk failure were determined. most common species Mycobacterium avium complex (MAC) (50%), M. abscessus (28%),...
To compare non-tuberculous mycobacterial pulmonary disease (NTMPD) diagnosis by metagenomic next-generation sequencing (mNGS) with Bactec growth indicator tube (MGIT) 960.A total of 422 patients suspected NTMPD in Shanghai Pulmonary Hospital between January 2020 and May 2021 were retrospectively analyzed; 194 diagnosed NTMPD. The diagnostic performance mNGS MGIT 960 for was assessed. Receiver operating characteristic (ROC) curves areas under curve (AUCs) compared.The sensitivity 81.4% higher...
Abstract Objective To evaluate the effectiveness and safety of linezolid-containing regimens for treatment M. abscessus pulmonary disease. Methods The records 336 patients with disease who were admitted to Shanghai Pulmonary Hospital from January 2018 December 2020 retrospectively analyzed. A total 164 received a regimen 172 controls did not. effectiveness, safety, antibiotic susceptibility profiles, outcomes, culture conversion, cavity closure, adverse reactions compared in these two...
Investigate the use of endobronchial ultrasonography with a guide sheath (EBUS-GS) combined Gene Xpert MTB/RIF (Xpert) for diagnosis Mycobacterium tuberculosis (MTB) infection in isolated pulmonary nodules.Patients who had nodules and unknown diagnoses at our institution from October 2020 to December 2021 were prospectively examined using EBUS-GS Xpert. The diagnostic values or bronchoalveolar lavage fluid (BALF) acid-fast staining, MGIT 960 culture, pathological examination, caused by MTB...
With the increase in depth of large-scale open-pit mining, many mines have to face problems such as what is effect blasting on rock slope and how ensure stability a high-steep slope. The east Beizhan iron mine Hejing County, Xinjiang, belongs typical high steep mined hanging-wall ore. To study vibrations stability, intelligent vibration detector was used monitor wave corresponding numerical model established. We fitted transmission law by Sodev’s regression formula calculated stress, strain,...
In the process of development and construction open‐pit mine slope in high altitude cold area, freeze‐thaw (F‐T) cycles have an important impact on rock engineering structure. F‐T lead to decrease physical mechanical properties rock, which is closely related stability slope. this paper, influence geomechanical acoustic emission (AE) characteristics tuff specimens under different stress paths was studied by using cycle treatment, situ AE monitoring, uniaxial loading test. The results...
Abstract Background The MeltPro TB assay (MeltPro) is a molecular rapid diagnostic test designed for detecting resistance to antituberculosis drugs. However, the performance of as an initial simultaneously presence Mycobacterium tuberculosis (MTB) and drug has not been evaluated. This study aims assess simultaneous detection MTB in clinical samples from patients with presumptive pulmonary (PTB). Methods A retrospective analysis was conducted on 1283 PTB two centers, out which 875 were...
The prefabricated urban utility tunnels (UUTs) have many advantages such as short construction period, low cost, high quality, and small land occupation. However, there is still a lack of in‐depth analysis the mechanical performance tunnel (UUT) structure with bolted connections under different working conditions. In this paper, force UUT in Tongzhou District, Beijing, was studied conditions using two methods: field monitoring numerical simulation. multichannel strain monitor used for...
This article develops one new test technology, dumbbell method, for evaluation of the early age cracking property Concrete Material under constraint conditions. Its exercise stress risers could lead concrete to crack quickly, providing a quick method evaluate performance material and perform simulated at job site conveniently. By this anti-cracking different can be evaluated quickly in construction site.
With the rapid development of infrastructure construction in western China where hilly and gully areas are distributed, there lots large‐scale filling engineering recent years. In area collapsible loess is widely it inevitable to use as material. Considering collapsibility loess, centrifuge model tests were conducted study settlement fill a valley after subjected rainfall infiltration. To provide comparison, test body on flat ground was conducted, results showed that during stage larger than...
Abstract Objective Investigate the use of endobronchial ultrasonography with a guide sheath (EBUS-GS) combined Gene Xpert MTB/RIF (Xpert) for diagnosis Mycobacterium tuberculosis (MTB) infection in isolated pulmonary nodules. Methods Patients who had nodules and unknown diagnoses at our institution from October 2020 to December 2021 were prospectively examined using EBUS-GS Xpert. The diagnostic values or bronchoalveolar lavage fluid (BALF) acid-fast staining, MGIT 960 culture, pathological...
Abstract By conducting collapsibility test, the changing rule of coefficient remolded loess is obtained. According to numerical simulation method equivalent humidity field with temperature field, converted into change, so calculation wetting settlement realized. The results show that decreases significantly increase compaction degree and initial water content. It increases first then overlying pressure at lower degree, while gradually higher degree. based on theory can accurately simulate test loess.
Abstract Background The MeltPro TB assay (MeltPro) is a molecular rapid diagnostic test designed for detecting resistance to antituberculosis drugs. However, the performance of as an initial simultaneously presence Mycobacterium tuberculosis (MTB) and drug has not been evaluated. This study aims assess simultaneous detection MTB in clinical samples from patients with presumptive pulmonary (PTB). Methods A retrospective analysis was conducted on 1283 PTB two centers, out which 875 were...
Abstract To better predict the deformation of high loess-filled foundation, values parameters each layer in foundation are obtained using changing modulus-iterative method. Based on parameters, during construction was calculated ideal elastoplastic constitutive model and visco-elastoplastic model. Comparison between predicted measured results indicates that suitable for predicting foundation.