A5032447319- Retinal Diseases and Treatments
- Psoriasis: Treatment and Pathogenesis
- Proteoglycans and glycosaminoglycans research
- ATP Synthase and ATPases Research
- Advanced Glycation End Products research
- Mitochondrial Function and Pathology
- Toxoplasma gondii Research Studies
- Complementary and Alternative Medicine Studies
- Cancer Immunotherapy and Biomarkers
- Connexins and lens biology
- Immunotherapy and Immune Responses
- Antimicrobial Peptides and Activities
- Cell death mechanisms and regulation
- Ocular Diseases and Behçet’s Syndrome
- T-cell and B-cell Immunology
- Vitamin D Research Studies
- Biochemical Acid Research Studies
University of Ferrara
2022-2024
University of California, San Diego
2023
Advances in immunotherapy the last decade have revolutionized treatment paradigms across multiple cancer diagnoses. However, only a minority of patients derive durable benefit and progress with traditional approaches, such as vaccines, remains unsatisfactory. A key to overcoming these barriers resides deeper understanding tumor antigen presentation complex dynamic heterogeneity tumor-infiltrating antigen-presenting cells (APCs). Reminiscent ‘second touch' hypothesis proposed by Klaus Ley for...
Papadas, A., Huang, Y., Cicala, Dou, Fields, M., Gibbons, Hong, D., Lagal, D.J., Quintana, V., Rizo, Zomalan, B. and Asimakopoulos, F. (2023) Emerging roles for tumor stroma in antigen presentation anti-cancer immunity. Biochem. Soc. Trans.51: 2017–2028. doi: https://doi.org/10.1042/BST20221083The authors would like to correct a passage of text from the "Dual non-cellular stromal actor: contrast between immunoregulatory proteoglycan versican versus its immunostimulatory proteolytic fragment,...
Hyperglycaemia and increased circulating saturated fatty acids are key metabolic features of type 2 diabetes mellitus (T2DM) that contribute to diabetic retinopathy pathogenesis. Contrarily, tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) has been shown improve or prevent T2DM. This study aimed at investigating the effect TRAIL in an vitro model human retinal pigment epithelium: ARPE-19 cell line, treated with palmitic acid (PA) presence high glucose concentration. PA...