Chongxiang Chen

ORCID: 0000-0002-2079-881X
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About
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Research Areas
  • Tracheal and airway disorders
  • RNA modifications and cancer
  • Lung Cancer Diagnosis and Treatment
  • Obstructive Sleep Apnea Research
  • SARS-CoV-2 and COVID-19 Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Esophageal and GI Pathology
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies
  • Neuroscience of respiration and sleep
  • Advanced Glycation End Products research
  • Inflammatory Biomarkers in Disease Prognosis
  • Immune Response and Inflammation
  • Intensive Care Unit Cognitive Disorders
  • Sepsis Diagnosis and Treatment
  • Cancer-related gene regulation
  • Cancer survivorship and care
  • Cancer therapeutics and mechanisms
  • Genetic Associations and Epidemiology
  • Gastrointestinal motility and disorders
  • Respiratory Support and Mechanisms
  • Enhanced Recovery After Surgery
  • Dysphagia Assessment and Management
  • Alcohol Consumption and Health Effects
  • Sleep and Wakefulness Research

First Affiliated Hospital of Guangzhou Medical University
2019-2025

State Key Laboratory of Respiratory Disease
2019-2025

Guangzhou Medical University
2019-2025

Sun Yat-sen University
2017-2023

Sun Yat-sen University Cancer Center
2017-2023

Guangzhou Development Zone Hospital
2023

State Key Laboratory of Oncology in South China
2019-2021

Third Affiliated Hospital of Guangzhou Medical University
2020

Ovarian cancer is a frequently-occurring reproductive system malignancy in females, which leads to an annual of over 100 thousand deaths worldwide.The electronic databases, including GEPIA, ONCOMINE, Metascape, and Kaplan-Meier Plotter, were used examine both survival transcriptional data regarding the cell division cycle associated (CDCA) gene family among ovarian patients.All CDCA genes expression levels up-regulated tissues relative those non-carcinoma counterparts. Besides, CDCA5/7...

10.21037/atm.2020.01.99 article EN Annals of Translational Medicine 2020-03-01

We report a case of tracheobronchial amyloidosis (TBA) in 55-year-old woman with newly diagnosed primary Sjögren’s syndrome (SS), presenting persistent cough, hemoptysis, and dry mucosal symptoms. Chest CT showed thickened airway walls cystic lung changes, while bronchoscopy revealed nodular lesions exposed vessels. Congo red staining confirmed amyloid deposition κ light-chain dominance, consistent AL amyloidosis. Despite immunosuppressive therapy, persisted, highlighting the challenge...

10.1177/17534666251342145 article EN cc-by-nc Therapeutic Advances in Respiratory Disease 2025-05-01

The objective of this study was to conduct a meta-analysis comparing neurally adjusted ventilatory assist (NAVA) with pressure support ventilation (PSV) in adult ventilated patients patient-ventilator interaction and clinical outcomes.The PubMed, the Web Science, Scopus, Medline were searched for appropriate trials (CTs) NAVA PSV patients. RevMan 5.3 performed asynchrony index (AI), ineffective efforts, auto-triggering, double asynchrony, premature breathing pattern (Peak airway (Pawpeek),...

10.21037/atm.2019.07.60 article EN Annals of Translational Medicine 2019-08-01

Artificial intelligence (AI) technology has been used for finding lesions via gastrointestinal endoscopy. However, there were few AI-associated studies that discuss bronchoscopy.To use convolutional neural network (CNN) to recognize the observed anatomical positions of airway under bronchoscopy.We designed study by comparing imaging data patients undergoing bronchoscopy from March 2022 October using EfficientNet (one CNNs) and U-Net.Based on inclusion exclusion criteria, 1527 clear images...

10.1177/20406223231181495 article EN cc-by-nc Therapeutic Advances in Chronic Disease 2023-01-01

Septic shock is one of the major healthcare problems, affecting millions people around world every year. The object this study to find best kind regimen vasopressors treatment in septic shock.The PubMed, and Web Science were used included studies. Stata 15.1 was performed systemic review network meta-analysis.After searching screening articles, finally we articles about 31 randomized controlled trials (RCTs), 11 arms (dopamine, dopexamine, epinephrine, norepinephrine, norepinephrine +...

10.21037/atm.2019.09.134 article EN Annals of Translational Medicine 2019-10-01

The objective of this study was to determine the causal relationship between habitual alcohol consumption with meals and lung cancer.Public genetic summary data from two large consortia [the Neale Lab International Lung Cancer Consortium (ILCCO)] were used for analysis. As instrumental variables meals, on variants retrieved Lab. Additionally, other [Global Lipid Genetics (GLGC), Tobacco, Alcohol (TAG), Genetic Investigation Anthropocentric Traits (GIANT)] utilized whether could causally...

10.21037/atm-20-3063 article EN Annals of Translational Medicine 2021-02-01

Background: Given the rarity of tracheobronchopathia osteochondroplastica (TO), many young doctors in primary hospitals are unable to identify TO based on bronchoscopy findings. Objectives: To build an artificial intelligence (AI) model for differentiating from other multinodular airway diseases by using bronchoscopic images. Design: We designed study comparing imaging data patients undergoing January 2010 October 2022 EfficientNet. Bronchoscopic images 21 with at Anhui Chest Hospital 2019...

10.1177/17534666241253694 article EN cc-by-nc Therapeutic Advances in Respiratory Disease 2024-01-01

Anthropometric measurements are simple and reachable tools for self-evaluating screening patients with a high risk of obstructive sleep apnea (OSA). However, the accumulated relationship obesity on anthropometric characteristics OSA is not well understood. The aim study was to show time-dependent trend compare overall regional between two ethnicities.A cumulative meta-analysis performed assess metrics in without Asians Caucasians. We searched PubMed, Web Science, Embase, Scopus up Jun 2020....

10.21037/jtd-20-1799 article EN Journal of Thoracic Disease 2021-03-01

The objective of this network meta-analysis was to determine the most useful first-line therapeutic strategy for patients with advanced (IIIB/IV or relapsed) non-small cell lung cancer (NSCLC) epidermal growth factor receptor (EGFR) Leu858Arg EGFR 19del mutations.PubMed, Web Science, Medline, and reports top three world conferences (WCLC, ESMO, ASCO) were searched appropriated randomized controlled studies (RCTs) discussing use various generations tyrosine kinase inhibitors (TKIs; gefitinib,...

10.1177/20406223221125706 article EN cc-by-nc Therapeutic Advances in Chronic Disease 2022-01-01

Aim. To analyze whether the change of laboratory tests (postoperative day 1 (POD1) minus pre-operation) could be predictive factors for postoperative infection in patients who have undergone McKeown esophagogastrectomy. Methods. We retrospectively investigated clinical data 358 esophagogastrectomy, and divided them into noninfection groups. SPSS 22.0 software was performed analysis. Results. In two groups, smoking status (66.7% vs. 42.3%; <mml:math...

10.1155/2019/9718705 article EN BioMed Research International 2019-10-22

Background: Several studies show that autophagy plays an important part in the biological processes of lung adenocarcinoma. Therefore, this work aimed to establish one scoring system on basis expression profiles differentially expressed autophagy-related genes (DEARGs) patients with adenocarcinoma.Methods: The Cancer Genome Atlas (TCGA) was applied retrieve adenocarcinoma data. overall survival (OS)-associated DEARGs were selected for DEARG scale. Moreover, online database Kaplan-Meier...

10.21037/tcr.2020.02.07 article EN Translational Cancer Research 2020-03-01

Abstract With the wide application of one-key sequence control in intelligent substations, testing sequential and error prevention logic has become an important work before production. Due to limitation methods, most tests are conducted during on-site commissioning, which a large workload, lower efficiency, high probability missed testing. Therefore, this paper proposes full-automatic test system for substation based on GOOSE/SV signal simulation. It can automatically verify monitoring...

10.1088/1742-6596/2488/1/012049 article EN Journal of Physics Conference Series 2023-05-01
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