A5033325662- Multiple Myeloma Research and Treatments
- Protein Degradation and Inhibitors
- Hematopoietic Stem Cell Transplantation
- Neutropenia and Cancer Infections
- Chronic Lymphocytic Leukemia Research
- Malaria Research and Control
- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Chronic Myeloid Leukemia Treatments
- Blood donation and transfusion practices
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- T-cell and B-cell Immunology
- Eosinophilic Disorders and Syndromes
- Lymphadenopathy Diagnosis and Analysis
- Complement system in diseases
- Histiocytic Disorders and Treatments
- Cancer Risks and Factors
- Platelet Disorders and Treatments
- Acute Myeloid Leukemia Research
- Renal Diseases and Glomerulopathies
- Global Health and Epidemiology
- CNS Lymphoma Diagnosis and Treatment
- Hemoglobinopathies and Related Disorders
- Hematological disorders and diagnostics
King Abdullah International Medical Research Center
2020-2024
National Guard Health Affairs
2019-2024
King Abdulaziz Medical City
2017-2024
King Saud bin Abdulaziz University for Health Sciences
2017-2024
Saudi Center for Organ Transplantation
2024
King Faisal Specialist Hospital & Research Centre
2014
University of Ottawa
2011
Ottawa Hospital
2011
Background Multiple myeloma (MM) is a plasma cell malignancy with significant unmet medical needs, particularly in the treatment of relapsed and refractory disease. This study aims to describe disease characteristics, various regimens, outcomes among patients Relapsed/Refractory Myeloma (RRMM) Greater Gulf region. Methods A regional, retrospective was conducted countries collect real-world data from records 148 RRMM who 1–3 times past two years before collection period (July 2022 February...
The development of hematopoietic stem cell transplantation (HSCT) programs can face significant challenges in most developing countries because such endeavors must compete with other government health care priorities, including the delivery basic services. While this is may be a limiting factor, these should prioritize needed expertise to offer state art treatments transplantation, by providing financial, technological, legal, ethical and support. This would prove beneficial successful...
BACKGROUND AND OBJECTIVES: There is limited information regarding the outcome of patients treated for leukemia during pregnancy. This study was performed on all cases pregnancy identified in our institution database. PATIENTS METHODS: It a retrospective from existing Thirty two were among cohort acute and chronic between January 1991 July 2003. RESULTS: Among ( n = 21), 10 (47.6%) received chemotherapy pregnancy, seven had live birth three spontaneous abortion. No teratogenicity or...
Background Multiple myeloma (MM) is the second-most common cancer among hematological malignancies. Patients with active disease may experience several comorbidities, including renal insufficiency and asthma, which lead to treatment failure. The of relapsed or refractory MM (RRMM) has been associated multiple factors, causing a decline in progression-free survival as well overall subsequent lines therapy. Data about characteristics this group patients Greater Gulf region are lacking....
Erdheim-Chester disease (ECD) is a rare type of non-Langerhans cell histiocytosis, with only 550 cases reported worldwide. ECD characterized by diffuse histiocytic infiltration multiorgans. The age presentation this typically between 40 and 70 years. Bone the most common symptom, as unique radiological findings long bone sclerosis occur in 96% cases. Furthermore, BRAF V600E mutation detected 60% In manuscript, we are describing case ECD; patient younger than has no pain or any skeletal...
Peripheral blood stem cell (PBSC) collection from donors through apheresis has become the main source of cells for hematopoietic transplantation. This procedure requires a high flow venous access. A peripheral catheter (PVC), compared to central (CVC), is considered provide safer However, initially at our institution, King Abdul-Aziz Medical City - Riyadh, CVC was frequently used (72%). quality improvement multidisciplinary team been formed conduct systematic performance analysis evaluate...
The Saudi Lymphoma Group had previously published recommendations on the management of major subtypes lymphoma. However, effect currently ongoing coronavirus disease 2019 (COVID-19) pandemic has patients with lymphoma been paramount. Therefore, decided to provide clinical practice guidelines for diagnosis, and follow-up various types during COVID-19 pandemic.
Acquired thrombotic thrombocytopenic purpura (aTTP) is a life-threatening microangiopathy usually characterized by microangiopathic hemolytic anemic, thrombocytopenia, and end-organ ischemia associated with disseminated microvascular platelet-rich thrombi severe deficiency (activity <10%) of A Disintegrin-like And Metalloprotease ThromboSpondin Type 1 Motif No. 13 (ADAMTS13). It medical emergency, if left untreated, acute mortality as high 90%. This review article narrative based on...
Introduction: The rapidly expanding treatment landscape for Chronic Lymphocytic Leukemia (CLL) calls appropriate patient and selection sequencing with existing agents. Data describing CLL management are fragmented across different regions, marked cross-country differences in practices outcomes. Therefore, we have established the observational study CREEK, retrospective real-world evidence key data from Middle East North Africa, Asia, Latin America. This interim analysis aimed to describe...
7 Background: There has been a shift towards the utilization of outpatient delivery intensive chemotherapy due to potential improvements in quality life measures and resource utilization. Herein, we aim report findings five-year improvement project comparing outcomes healthcare costs inpatient post-induction amongst patients with hematological neoplasms. Methods: Using Plan-Do-Study-Act (PDSA) methodology, multidisciplinary team was established determine appropriate strategies for delivering...
<sec> <title>BACKGROUND</title> Multiple myeloma (MM) is the second-most common cancer among hematological malignancies. Patients with active disease may experience several comorbidities, including renal insufficiency and asthma, which lead to treatment failure. The of relapsed or refractory MM (RRMM) has been associated multiple factors, causing a decline in progression-free survival as well overall subsequent lines therapy. Data about characteristics this group patients Greater Gulf region...
Multiple myeloma (MM) is neoplasm of the plasma cells derived from postgerminal B-cell lineage and it ranges premalignant conditions like monoclonal gammopathy unknown significance smoldering MM (SMM) to malignant diseases such as overt MM. With advances in science technology, understanding disease has increased paving way for advanced therapeutic options better patient outcomes. Thus, this article a narrative review summarizing recent epidemiology, clinical presentation, risk...
Introduction: Autologous stem cell transplantation (ASCT) prolongs progression free survival (PFS) in newly diagnosed multiple myeloma (MM) patients the era of novel therapy. However, outcome MM from Middle East and North Africa (MENA) is much less known due to paucity SCT centers. Methods: This a retrospective analysis all that underwent ASCT at our center. All data were retrieved electronic medical records. Baseline patient characteristics, disease treatment related variables reported...