A5036816340- Nanoparticle-Based Drug Delivery
- Characterization and Applications of Magnetic Nanoparticles
- Iron oxide chemistry and applications
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Kruppel-like factors research
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Microfluidic and Bio-sensing Technologies
- Acute Myeloid Leukemia Research
- Erythrocyte Function and Pathophysiology
- Extracellular vesicles in disease
Krasnoyarsk Scientific Center
2021-2024
National Medical Research Center for Hematology
2021
Ministry of Health of the Russian Federation
2021
Abstract Exosomes are a type of membrane vesicle secreted into the extracellular medium by most cell types. They have great potential for clinical practice as noninvasive biomarkers diagnosis various diseases, prognosis, and monitoring therapy, which stimulates development simple methods isolating exosomes from biological fluids. A novel affine material based on aminosilanized superparamagnetic core‒shell nanoparticles fast isolation urinary is reported. Iron oxide coated with amino...
Iron oxide nanoparticles were synthesized by the coprecipitation method. Two varying Fe3O4/tetraethoxysilane ratios used for silanization: 1:1.3 and 1:4.5. The samples investigated using transmission electron microscopy, ferromagnetic resonance, IR spectroscopy, magnetometry. Magnetic measurements have shown that magnetite core in has a higher magnetization than stoichiometric of same size. increased was caused deviation stoichiometry due to interaction with silicate coating. blocking...
Aim: To develop magnetic nanoparticles (MNPs) based on iron oxide for DNA isolation from blood cells quantitative molecular genetic analyses of the V617F mutation in Januskinase 2 (JAK2) gene. Materials and Methods: MNPs were synthesized by coprecipitation method coated with tetraethyl orthosilicate (TEOS). The size shape complexes estimated using transmission electron microscopy. Twenty samples patients myeloproliferative disorders used MNPs. quality compatibility studies JAK2 investigated...