A5083515343- Doping in Sports
- Hormonal and reproductive studies
- Muscle metabolism and nutrition
- Sexual Differentiation and Disorders
- Genetics and Physical Performance
- Sports, Gender, and Society
- Cardiovascular Effects of Exercise
- CRISPR and Genetic Engineering
- Muscle and Compartmental Disorders
- Virus-based gene therapy research
- Molecular Biology Techniques and Applications
- LGBTQ Health, Identity, and Policy
- Sports Analytics and Performance
University of Brighton
2018-2023
Foro Italico University of Rome
2020
Bridge University
2020
University of Essex
2020
One of the most contentious issues in modern day sport arises when sports are divided into male and female categories. The International Association Athletics Federations' (IAAF) previous policy regulating intersex athletes was suspended by Court Arbitration for Sport (CAS), resulting a new policy. challenge faced governing body athletics is to formulate that upholds both international law Olympic charter stipulates compete without discrimination any kind. Implementation has been delayed...
Abstract Background The pervasiveness of doping and findings anti-doping corruption threaten weightlifting’s position at the 2024 Olympic Games. Analysing practices in weightlifters could identify patterns that assist future detection. Methods We analysed publicly available data on sanctioned athletes/support personnel from International Weightlifting Federation between 2008 2019 announced retrospective Anti-Doping Rule Violations (ADRVs) 2012 Results There were 565 sanctions which 82%...
The coronavirus disease (COVID-19) pandemic has had an unprecedent impact on the world of sport and society at large. Many challenges with respect to integrity previously facing competitive have been accentuated further during pandemic. Threats sporting competition include traditional doping, issues technological fairness, integration transgender intersex athletes in elite sport. enforced lull provides unprecedented opportunity for stakeholders focus unresolved develop implement long-lasting...
Abstract Background The effects of Anabolic Androgenic Steroids (AAS) are largely illustrated through Androgen Receptor induced gene transcription, yet RNA-Seq has to be conducted on human whole blood and skeletal muscle. Investigating the transcriptional signature AAS in may aid detection muscle further understanding hypertrophy. Methods Males aged 20–42 were recruited sampled once: sedentary controls (C), resistance trained lifters (RT) current users (RT-AS) who ceased exposure ≤ 2 or ≥ 10...
Introduction: Recombinant human erythropoietin (rHuEPO) administration studies involving transcriptomic approaches have demonstrated a gene expression signature that could aid blood doping detection. However, current anti-doping testing does not involve collecting whole into tubes with RNA preservative. This study investigated if in long-term storage and left over from standard hematological short-term be used for analysis despite lacking preservation. Methods: Whole samples were collected...
Objective: It remains unknown whether myonuclei remain elevated post anabolic-androgenic steroid (AAS) usage in humans. Limited data exist on AAS-induced changes gene expression. Design: Cross-sectional/longitudinal. Setting: University. Participants: Fifty-six men aged 20 to 42 years. Independent Variables: Non–resistance-trained (C) or resistance-trained (RT), RT currently using AAS (RT-AS), of which if ceased for ≥18 weeks resampled as Returning Participants (RP) previously (PREV). Main...
Abstract Androgens are vital for the maintenance of muscle mass and their anabolic effects primarily exerted through androgen receptor (AR). Accumulating evidence in humans mice suggests that circulating androgens, AR response influenced by ACTN3 ( α- actinin-3), also known as “the gene speed”. One 5 people worldwide α-actinin-3 deficient due to homozygous inheritance a common null polymorphism (577X) . In this study, we show deficiency decreases baseline skeletal muscles humans, both males...
Introduction: The issue of integrating transgender athletes into sport is becoming more prominent with the rising numbers those identifying as in society. Whether it fair for to be included their affirmed gender category across all levels from grassroots elite crux debate. Previous studies have shown muscle mass loss transwomen and strength gain transmen after 1 year gender-affirming treatment (GAT). Wiik et al., 2020 found that retain a disadvantage over cisgender men advantages women GAT....
Abstract Background: The pervasiveness of doping and findings anti-doping corruption threaten weightlifting’s position at the 2024 Olympic Games. Analysing practices in weightlifters could identify patterns that assist future detection. Methods: We analysed publicly available data on sanctioned athletes/support personnel from International Weightlifting Federation between 2008-2019 announced retrospective Anti-Doping Rule Violations (ADRVs) 2008 2012 Results: There were 565 sanctions which...
Abstract Background: The pervasiveness of doping and findings anti-doping corruption threaten weightlifting’s position at the 2024 Olympic Games. Analysing practices in weightlifters could identify patterns that assist future detection. Methods: We analysed publicly available data on sanctioned athletes/support personnel from International Weightlifting Federation between 2008-2019 announced retrospective Anti-Doping Rule Violations (ADRVs) 2008 2012 Results: There were 565 sanctions which...
Abstract Background The pervasiveness of doping and findings anti-doping corruption threaten weightlifting’s position at the 2024 Olympics. Analysing practices weightlifters could identify patterns in that assist future detection. Methods We analysed publicly available data on sanctioned athletes/support personnel from International Weightlifting Federation (IWF) between 2008–2019 retrospective Anti-Doping Rule Violations (ADRVs) 2008 2012 Results There were 565 sanctions which 82% related...