- Forensic Toxicology and Drug Analysis
- Plant-based Medicinal Research
- Metabolomics and Mass Spectrometry Studies
- Bioactive Natural Diterpenoids Research
- Analytical Chemistry and Chromatography
- Traditional Chinese Medicine Analysis
- Analytical Methods in Pharmaceuticals
- Neurotransmitter Receptor Influence on Behavior
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Electron Spin Resonance Studies
- Cannabis and Cannabinoid Research
- Natural product bioactivities and synthesis
- Insect and Pesticide Research
- Bacterial Identification and Susceptibility Testing
- Poisoning and overdose treatments
- Chromatography in Natural Products
- Marine Toxins and Detection Methods
- Biological Activity of Diterpenoids and Biflavonoids
- Ion channel regulation and function
- Fungal Plant Pathogen Control
- Neonatal Health and Biochemistry
- Methemoglobinemia and Tumor Lysis Syndrome
- Advanced Chemical Sensor Technologies
- Cassava research and cyanide
National Forensic Institute
2013-2023
Animal and Plant Quarantine Agency
2023
Chungbuk National University
2013
The ERETIC (Electronic REference To access In vivo Concentrations)2 method is a new qNMR experimental technique to measure analytes based on the signal of reference compound without additional hardware equipment. this study, ERETIC2 was validated, and we sought identify whether it would be possible apply specific analysis metabolites in plant. <TEX>$90^{\circ}$</TEX> pulse value (P1) spin-lattice relaxation time (<TEX>$T_1$</TEX>) each were measured for ERETIC2. <TEX>$9^1H$</TEX>...
The purpose of this study was to investigate whether there is an association between grayanotoxin levels in urine and blood patients with mad honey intoxication the consumed, resulting clinical picture. pilot data acquired from analysed National Forensic Service, Daejeon Institute, South Korea first results were published as a preliminary study.This descriptive conducted at university hospital emergency department Turkey. 25 cases diagnosed obtained study. Samples consumed by obtained. Blood...
Intoxications related to "mad honey" are frequently encountered in the Black Sea region of Turkey. Intoxication is established on basis whether honey was consumed when history taken at presentation. The search for a simple and reliable method showing grayanotoxins (GTXs) mad body fluids by patients still research stage. purpose this preliminary study investigate GTX levels blood, urine, with intoxication determine there an association clinical status.This descrptive conducted department...
A sensitive and specific high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the determination of Grayanotoxin I (GTX I) III III) in rat whole blood. Grayanotoxins (GTXs) clindamycin as internal standard (IS) were extracted from blood via solid-phase extraction using PEP cartridges. Chromatographic separation analytes achieved on a Kinetex C18 (100 × 2.1 mm, 2.6 µm) reversed-phase column gradient elution with mobile phase 1% acetic acid water...
Cyanide is a highly toxic agent that has been frequently used for suicide in South Korea. It also various industrial fields, such as metal plating, which many accidental cyanide intoxications have occurred. To overcome the disadvantages of conventional analysis methods, simple and fast method whole blood using ion chromatography (IC) with amperometric detection was developed this study. Whole samples were deproteinized, diluted, analyzed an IC-amperometric system. The limits quantitation 0.1...
Angelica gigas, a popular medicinal herb in Korea, is locally called Danggui; this name similarly used for acutiloba and sinensis, which are also sold the retail market. These three herbs have differing therapeutic effects should be according to their prescribed purposes. In some markets, though, all known by same common rather than scientific can therefore confused with each other. particular, case of powdered products, intentional or unintentional wrong sales activity seller may occur....
In Korea, Angelica gigas is commonly known as Danggui. However, two other species on the market, acutiloba and sinensis, are also called Since three have different biologically active components, thus, pharmacological activities, clear discrimination between them needed to prevent their misuse. A. used not only a cut or powdered product but in processed foods, where it mixed with ingredients. To discriminate species, reference samples were analysed non-targeted using liquid...
For a case study of suspected paraquat intoxication, we developed simple and rapid method <TEX>$^1H$</TEX> qNMR to determine the mili-molar amount in postmortem blood samples. There were no interfering signals from endogenous compounds chemical shift diquat (internal standard). The sample used ranged 0.25 mM 10.0 mM. Diquat, which has similar physicochemical properties with paraquat, was chosen as an internal standard. NMR experimental conditions, relaxation delay time CPMG spin-echo pulse...
A 62-year-old male transferred to a hospital emergency room mentioned that he had drunk liquor extract from ‘Pokeberry’ (Phytolacca americana). The was summited, dehydrobrownine and delphatine, which were found in plants of the genus Delphinium, detected via gas chromatography-mass spectrometry (GCMS). High-resolution quadrupole time-of-flight/mass (QTOF/MS) can be used for toxicant identification without reference materials, exact mass target compound MSMS fragmentation isotope ratios...