Olla A. Khalifa

ORCID: 0000-0002-2783-6962
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Antioxidant Activity and Oxidative Stress
  • Wound Healing and Treatments
  • Periodontal Regeneration and Treatments
  • Selenium in Biological Systems
  • Tissue Engineering and Regenerative Medicine
  • Dietary Effects on Health
  • Diet and metabolism studies
  • Trace Elements in Health
  • Electrospun Nanofibers in Biomedical Applications
  • Immune Response and Inflammation
  • Bioactive Compounds and Antitumor Agents
  • RNA Interference and Gene Delivery
  • Forensic Entomology and Diptera Studies
  • Urological Disorders and Treatments
  • Rabbits: Nutrition, Reproduction, Health
  • Aquaculture Nutrition and Growth
  • DNA and Nucleic Acid Chemistry
  • Liver Disease and Transplantation
  • Mesenchymal stem cell research
  • Liver Disease Diagnosis and Treatment
  • Livestock and Poultry Management
  • Hernia repair and management
  • Reconstructive Surgery and Microvascular Techniques
  • Drug-Induced Hepatotoxicity and Protection

Benha University
2016-2024

Broilers are continuously stressed because of the rapid growth rate and environmental issues associated with industrialized poultry production systems, which lead to higher susceptibility for infection pathogens. It is well known that vitamin E (Vit. E) selenium (Se) supplementation have protective functions in such stressful conditions. This protocol was investigate impact Vit. and/or Se on performance, some serum biochemistry, expression growth-related gene liver tissue broilers. The...

10.1186/s12917-021-02963-1 article EN cc-by BMC Veterinary Research 2021-07-21

In contrast to free radicals, the first line of protection is assumed be vitamin E and selenium. The present protocol was designed assess roles and/or a selenium-rich diet that affected blood iron copper concentrations, liver tissue antioxidant lipid peroxidation, gene expression linked antioxidants in broilers. young birds were classified according dietary supplement into four groups; control, (100 mg Vitamin/kg diet), selenium (0.3 sodium selenite/kg pulse vitamin/kg with 0.3 diet)...

10.1186/s12917-022-03411-4 article EN cc-by BMC Veterinary Research 2022-08-13

Renal replacement therapy, either by transplantation or dialysis, is not accessible in many parts of the world because lack financial and clinical resources. This study was performed to investigate nephroprotective efficiency gum arabic (GA) lemongrass (LG) on adenine-induced chronic kidney disease. Four animal groups (each 10 rats) received normal saline, intraperitoneal injection adenine (300 mg/kg) twice a week, plus oral GA (5.4 g/kg) LG (360 daily for 4 weeks. Compared control group,...

10.1186/s42269-019-0086-x article EN cc-by Bulletin of the National Research Centre/Bulletin of the National Research Center 2019-03-25

Hepatic encephalopathy is a profound systemic consequence of liver insufficiency with neuropsychiatric symptoms, and in severe cases, coma death developed (Vilstrup et al., 2014).The mortality rate HE ranging from 50-90% patients allover the world (Raghavan Marik, 2006).Normally, can detoxify endogenous exogenous ammonia into urea.Once fails, hyperammonemia occurs, passes blood-brain barrier (Felipo Butterworth, 2002).Glutamine synthase catalyze synthesis glutamine which accumulates inside...

10.22587/ajbas.2019.13.4.1 article EN AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES 2019-01-01

This study involves the use of a new multifunctional prosthetic mesh for treatment perineal hernia without complications. The is hybrid platform both synthetic and natural materials, mainly consisting commercial polyester fabric (CPF) to deliver required mechanical integrity. CPF was coated by biodegradable, biocompatible, antimicrobial layer chitosan incorporating phenytoin-loaded pluronic nanomicelles healing promotion ciprofloxacin-alginate polyelectrolyte complex-based microparticles as...

10.5455/ovj.2022.v12.i1.15 article EN cc-by-nc Open Veterinary Journal 2022-01-01

Platelet rich plasma (PRP) and platelet fibrin (PRF) are considered excellent concentrated sources of growth factors (PDGF, TGF-β, VEGF, bFGF) cytokines fundamental for wound healing.The aim this study was to evaluate compare the effect PRP PRF on second intention healing through clinical vision, histopathological examination, changes in interleukin 10 (IL10) transforming factor-β (TGF-β) genes expression.Fifteen adult dogs were used study: induction a 3 cm diameter total thickness cutaneous...

10.21608/bvmj.2021.92616.1465 article EN Benha Veterinary Medical Journal 2021-10-01

The current protocol investigated how nucleotides and/or β-glucan affect antioxidant-related gene expression, hepatic tissue lipid peroxidation in chickens, and meat quality. newly hatched chicks were divided into four groups based on the nutritional supplements they received: first was a control group, second supplemented with 200 mg per kg of diet, third 1-gram kilogram fourth complemented both β-glucan. results demonstrated that expression substantially (P < 0.05) upregulated broiler...

10.21608/bvmj.2024.272774.1794 article EN cc-by Deleted Journal 2024-04-01

Synthetic Oligodeoxynucleotides (ODN) expressing CpG motifs (CpG-ODN) mimic the immunostimulatory activity of bacterial DNA and are commonly used to activate Toll Like Receptor 9 (TLR9) for therapeutic applications. CpG-ODN can counteract DNA-damaging chemotherapy radiation therapy on immune cell enhance immunity in preclinical mouse models. We hypothesized that these actions cells expressed by modulation repair genes. conducted a PCR array analysis genes expression splenocytes obtained from...

10.3844/ajbbsp.2016.159.170 article EN American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology 2016-03-01

This study was done on 81 rats to evaluate the post mortem interval PMI depending expression of Gapdh mRNA and protein response immunostaining.

10.5958/0973-9130.2019.00330.x article EN Indian Journal of Forensic Medicine & Toxicology 2019-01-01

WAT is where triglyceride stored primarily storage, while BAT specified for energy spending and has the ability to offset obesity [5,6] .There are two types isolated from subcutaneous fat: cultured/relatively homogeneous adipose-derived stromal/stem cells (ASCs), cultured/ heterogeneous stromal vascular fraction (SVF) [7] .Choukroun et al [8] was first report that Platelet Rich Fibrin (PRF) can be used in maxillofacial surgery.Platelet-rich fibrin formed when platelet cytokines, platelets...

10.21608/omx.2022.120106.1149 article EN Egyptian Journal of Oral & Maxillofacial Surgery 2022-04-01

Chronic wound healing is a severe problem in veterinary practice, therefore, new agent for recommended.Synthetic oligodeoxynucleotides containing one or more CpG motifs (CpG-ODN) are used to stimulate the immune system and improve skin healing.Ten clinically healthy animals were estimate compare rate of healing.The arranged into two groups (five each).The estimation was carried out by clinical observation signs 21 days, based on presence sepsis unhealthy granulation tissue...

10.21608/bjas.2022.253615 article EN Benha Journal of Applied Sciences 2022-04-01

Abstract A new trend of regenerative medicine was introduced recently in the field second intension wound healing. The PRP and PRF represented a corner stone this clinical practice, were it admit many factors for acceleration healing, enhancement epithelization neovascularization. are considered as great concentrated source growth (PDGF, TGF-β, VEGF, bFGF) cytokines which fundamental fro Nine adult dogs used study; we induced 3cm diameter full thickness cutaneous injury at right chest...

10.21203/rs.3.rs-179329/v1 preprint EN cc-by Research Square (Research Square) 2021-02-22

This research was undertaken in order to determine the impact of nutritional vitamin E on genetic expression Interferon-gamma (IFN-γ) and Interleukin-1β (IL-1β) as proinflammatory Interleukin-4 (IL-4) Interleukin-10 (IL-10) anti-inflammatory cytokines spleen liver, hemagglutination inhibition antibody titers (HI titers) against Newcastle Disease Virus (NDV), total protein, albumin, globulin, growth efficiency broiler chickens.Seventy-two one-day-old Cobb chicks had been allocated randomly...

10.21608/bvmj.2021.75450.1405 article EN Benha Veterinary Medical Journal 2021-07-01
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