A5101771375- Cancer-related gene regulation
- ATP Synthase and ATPases Research
- Prostate Cancer Treatment and Research
- RNA Interference and Gene Delivery
- Epigenetics and DNA Methylation
- Endometrial and Cervical Cancer Treatments
- Advanced biosensing and bioanalysis techniques
- Cytokine Signaling Pathways and Interactions
- Liver physiology and pathology
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Cancer, Hypoxia, and Metabolism
- Mitochondrial Function and Pathology
- TGF-β signaling in diseases
Jilin University
2023-2025
Augusta University Health
2024
Androgen deprivation therapy has been the primary treatment strategy for advanced prostate cancer (PCa). But most patients develop castration resistance over time. For FDA-approved second-generation androgen receptor (AR) antagonists, including enzalutamide (ENZ) and abiraterone (AA), who initially respond to them eventually resistance. The key mechanism ENZ/AA involves AR splice variants (AR-Vs) specifically AR-V7. Current antagonists cannot target AR-V7 due its lack of C-terminal...
Abstract Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) are the second most common cancers in women aged 20–39. While HPV screening can help with early detection of cervical cancer, many patients already medium to late stages when they identified. As a result, searching for novel biomarkers predict CESC prognosis propose molecular treatment targets is critical. TGFA polypeptide growth factor high affinity epidermal receptor. Several studies have shown that improve...
Abstract Septic cardiomyopathy is linked to a dysregulation in mitochondrial integrity and elevated mortality rates, for which an efficacious treatment remains elusive. PDS, panaxadiol saponin extracted from ginseng stem leaf. This study identified the protective effects of PDS DEX LPS-induced explored mechanism them treating perspectives quality control. enhance antioxidant defense by degrading Keap1 activate Nrf2, occurrence protein PGC-1α fusion OPA1, Mfn1, Mfn2 expression, inhibit...
Research on the function of HGH1 in breast cancer remains lacking.