A5101507436- RNA and protein synthesis mechanisms
- Plant tissue culture and regeneration
- Radioactivity and Radon Measurements
- Heat shock proteins research
- Epigenetics and DNA Methylation
- Receptor Mechanisms and Signaling
- Plant Molecular Biology Research
- Microbial bioremediation and biosurfactants
- Arsenic contamination and mitigation
- Cassava research and cyanide
- Crop Yield and Soil Fertility
- Environmental Toxicology and Ecotoxicology
- Chromium effects and bioremediation
- Photosynthetic Processes and Mechanisms
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Rheumatoid Arthritis Research and Therapies
- Genetics and Plant Breeding
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related gene regulation
- Bacterial biofilms and quorum sensing
- Enzyme-mediated dye degradation
- RNA Research and Splicing
- Biomedical Research and Pathophysiology
- Radioactive contamination and transfer
Quaid-i-Azam University
2023-2024
COMSATS University Islamabad
2010-2023
Institute of Biomedical and Genetic Engineering
2023
Pir Mehr Ali Shah Arid Agriculture University
2013-2014
Utrecht University
2013-2014
Glycine-rich RNA-binding proteins (GR-RBPs) are involved in cold shock response of plants as RNA chaperones facilitating mRNA transport, splicing and translation. GR-RBPs bipartite containing a recognition motif (RRM) followed by glycine-rich region. Here, we studied the structural basis nucleic acid binding full-length Nicotiana tabacum GR-RBP1. NMR studies NtGR-RBP1 show that domain, while intrinsically disordered, is responsible for mediating self-association transient interactions with...
Plant-parasitic nematodes infect the roots of crops which bring rigorous economic loss to food industry across globe. Several plant protection agents are being used but they cause severe negative environmental and health impacts. Recently, organic matter has become an important green alternative for several pesticides including nematicides. In present study, identification management stylet bearing associated with Malus pumila from different locations Khanpur, Pakistan, have been presented....
Background: Non-alcoholic fatty liver disease (NAFLD) is becoming quite common in Type II Diabetes Mellitus (TIIDM) as obesity and insulin resistance are within TIIDM it a widespread condition globally. This study evaluated the prevalence of NAFLD patients who also had type diabetes. Methods: The demographic data (name, age, body mass index (BMI), gender, occupation, duration TIIDM, treatment taking for TIIDM), well results tests these enzymes, were recorded. Alanine transaminase (ALT)...
Malathion, an organophosphorus insecticide, used around the world, can be harmful to environment because it doesn’t break down easily, especially in aquatic ecosystems. As accumulates these environments, cause serious damage, disrupting biodiversity and harming water quality. This study assessed genotoxic effects of malathion on blood cells grass carp (Ctenopharyngodon idella). Firstly, LC50 value for 96 hours’ exposure was identified 2.42 ppm. The fish were then subjected three varying...
Recent research has unveiled and confirmed the deleterious age-related changes of immune system which result in diminished ability older adults to effectively respond pathogens infection. This degradation is defined by term immunosenescence. Immunosenescence can also bring with it reduced vaccine efficacy. In an era where population growing exponentially, apparent why such dysfunction concerning. Adding even more pertinence COVID-19 pandemic. Since March 2020, across globe have borne witness...
G-protein couple receptors (GPCRs) are considered as the largest membrane protein family involved in regulation of body homeostasis health and disease. GPCR43 or FFA2 (free fatty acid receptor 2) is implicated diabetes. Efficient methods needed to express GPCRs for structural studies. Small GPCR fragments consisting 1-2 transmembrane domains routinely used NMR In present study, first three segments 1-3 (GPCR43-TM1-3) were cloned expressed with expression enhancement tag, AT4 His tag at C N...
Abstract Background Primary Hyperoxaluria Type 1 (PH1) is an autosomal recessive genetic disorder triggered by a mutation in the alanine glyoxylate aminotransferase (AGXT) gene. Early detection of PH1 pre-requisite as it causes End Stage Renal Disease (ESRD) most patients early stages. An eleven years old girl with history kidney disease and stones phenotypic characteristics was brought to laboratory. A c.568G>A AGXT gene, which responsible for PH1, found homozygous condition. Further...
The COVID-19 pandemic has illuminated a need for accessible, home-based therapies mental health. In an era of social distancing, lockdowns, and declining global health, one promising candidate is transcranial Direct Current Stimulation (tDCS). tDCS non-invasive, portable, targeted brain stimulation technique that uses electrical currents to modulate cortical excitability. It been heavily explored as treatment major depressive disorder (MDD) other health issues in recent years. However,...
Ultraviolet-visible (UV-Vis) spectroelectrochemistry (SEC) is a technique that enables simultaneous probing of the electrochemical behavior system and detection transmitted or reflected light indicative material chemical properties. UV-Vis SEC has found application in study lithium-ion batteries, metal-air electrocatalysis, electrochromic devices, to name few examples. For measurements using visible can be used determine state-of-charge electrode intercalation materials as function applied...