Lorenzo Iogna Prat
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Acute Myocardial Infarction Research
- Hormonal Regulation and Hypertension
Ospedale Santa Maria
2020
Ospedale Santa Maria della Misericordia di Udine
2019
University of Udine
2012
Abstract Aims To investigate the efficacy and safety of early transition from hospital to ambulatory treatment in low-risk acute PE, using oral factor Xa inhibitor rivaroxaban. Methods results We conducted a prospective multicentre single-arm investigator initiated academically sponsored management trial patients with PE (EudraCT Identifier 2013-001657-28). Eligibility criteria included absence (i) haemodynamic instability, (ii) right ventricular dysfunction or intracardiac thrombi, (iii)...
Introduction Early discharge of patients with acute low-risk pulmonary embolism requires validation by prospective trials clinical and quality-of-life outcomes. Methods The multinational Home Treatment Patients Low-Risk Pulmonary Embolism the Oral Factor Xa Inhibitor Rivaroxaban (HoT-PE) single-arm management trial investigated early followed ambulatory treatment rivaroxaban. study was stopped for efficacy after positive results predefined interim analysis at 50% planned population. present...
Objectives: Plasma aldosterone (PA) and some haemostatic factors are independent determinants of cardiac abnormalities in hypertension. The aim this study was to examine the relationships between plasma aldosterone, parameters left ventricular function mass essential hypertensive patients. Design methods: In 205 patients (age 48 ± 14 ys, 115 M/90F) we evaluated clinical characteristics, anthropometric parameters, PA, urinary active renin, renin ratio (ARR), levels fibrinogen (FBG), D-dimer,...