A5005566965- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- Transcranial Magnetic Stimulation Studies
- Motor Control and Adaptation
- EEG and Brain-Computer Interfaces
- Glycogen Storage Diseases and Myoclonus
- Muscle activation and electromyography studies
- Psychosomatic Disorders and Their Treatments
- Neuroscience and Neural Engineering
- Functional Brain Connectivity Studies
- Action Observation and Synchronization
- Obsessive-Compulsive Spectrum Disorders
- Neural dynamics and brain function
- Vestibular and auditory disorders
- Neural and Behavioral Psychology Studies
- Neurological and metabolic disorders
- Advanced Neuroimaging Techniques and Applications
- Autoimmune Neurological Disorders and Treatments
- Cerebral Palsy and Movement Disorders
- Attention Deficit Hyperactivity Disorder
- Neurology and Historical Studies
- Mental Health and Psychiatry
- Ophthalmology and Eye Disorders
National Institutes of Health
2016-2025
National Institute of Neurological Disorders and Stroke
2016-2025
Université Bourgogne Franche-Comté
2025
Government of the United States of America
2021-2024
John Wiley & Sons (United States)
2016-2024
Centre for Movement Disorders
2024
Bar-Ilan University
2023
Tel Aviv University
2023
Daiichi Sankyo (United States)
2022
Massachusetts General Hospital
1975-2021
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect expanding understanding this disease and its clinicopathologic correlations. An international consortium behavioral neurology, neuropsychology, movement disorders specialists developed new based on consensus a systematic literature review. Clinical diagnoses (early or late) were identified 267 nonoverlapping CBD cases from published reports brain banks. Combined with...
We applied trains of focal, rapid-rate transcranial magnetic stimulation (rTMS) to the motor cortex 14 healthy volunteers with recording EMG from contralateral abductor pollicis brevis, extensor carpi radialis, biceps brachii and deltoid muscles. Modulation amplitude evoked potentials (MEPs) produced in target muscle during rTMS showed a pattern inhibitory excitatory effects which depended on frequency intensity. With coil situated over optimal scalp position for activating led spread...
1. We used transcranial magnetic stimulation (TMS) to study the role of plastic changes human motor system in acquisition new fine skills. mapped cortical areas targeting contralateral long finger flexor and extensor muscles subjects learning a one-handed, five-finger exercise on piano. In second experiment, we studied different effects mental physical practice same modulation involved task. 2. Over course 5 days, as learned through daily 2-h manual sessions, enlarged, their activation...
The excitability of the human motor cortex during development implicit and declarative knowledge a task was examined. During serial reaction time test, subjects developed test sequence, which reflected by diminishing response times. Motor cortical mapping with transcranial magnetic stimulation revealed that output maps to muscles involved in became progressively larger until explicit achieved, after they returned their baseline topography. These results illustrate rapid functional plasticity...
Journal Article A PHYSIOLOGICAL MECHANISM OF BRADYKINESIA Get access MARK HALLETT, HALLETT From the Department of Neurology, Harvard Medical SchoolBoston, Mass. 02115, USASection Medicine, Peter Bent Brigham HospitalBoston, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar SHAHRAM KHOSHBIN Brain, Volume 103, Issue 2, June 1980, Pages 301–314, https://doi.org/10.1093/brain/103.2.301 Published: 01 1980 history Received: 06 1979
Imagining motor acts is a cognitive task that engages parts of the executive system. While imagery has been intensively studied using neuroimaging techniques, most studies lack behavioral observations. Here, we used functional MRI to compare neuroanatomy execution and objectively assesses performance. With surface electromyographic monitoring within scanner, 10 healthy subjects performed sequential finger-tapping movements according visually presented number stimuli in either movement or an...
1 We studied quiet stance investigating strategies for maintaining balance. Normal subjects stood with natural and feet together, eyes open or closed. Kinematic, kinetic EMG data were evaluated cross-correlated. 2 Cross-correlation analysis revealed a high, positive, zero-phased correlation between anteroposterior motions of the centre gravity (COG) pressure (COP), head COG, linear shoulder knee in both sagittal frontal planes. There was moderate, negative, motion COP ankle angular motion. 3...
<h3>Objective:</h3> To update the 2008 American Academy of Neurology (AAN) guidelines regarding botulinum neurotoxin for blepharospasm, cervical dystonia (CD), headache, and adult spasticity. <h3>Methods:</h3> We searched literature relevant articles classified them using 2004 AAN criteria. <h3>Results recommendations:</h3> Blepharospasm: OnabotulinumtoxinA (onaBoNT-A) incobotulinumtoxinA (incoBoNT-A) are probably effective should be considered (Level B). AbobotulinumtoxinA (aboBoNT-A) is...