A5023666752- Antimicrobial Peptides and Activities
- Rabies epidemiology and control
- Animal health and immunology
- Microbial infections and disease research
- Clinical practice guidelines implementation
- Olfactory and Sensory Function Studies
- Nicotinic Acetylcholine Receptors Study
- Ruminant Nutrition and Digestive Physiology
- Biochemical and Molecular Research
- Venomous Animal Envenomation and Studies
- Streptococcal Infections and Treatments
- Advanced Chemical Sensor Technologies
- Pneumocystis jirovecii pneumonia detection and treatment
- Effects of Environmental Stressors on Livestock
- Dermatology and Skin Diseases
- Cancer therapeutics and mechanisms
- Delphi Technique in Research
- Bee Products Chemical Analysis
- Tuberculosis Research and Epidemiology
- Insect and Pesticide Research
- Esophageal and GI Pathology
- Carbohydrate Chemistry and Synthesis
- Essential Oils and Antimicrobial Activity
- Antibiotic Resistance in Bacteria
- Otolaryngology and Infectious Diseases
University of Parma
2016-2021
Tuberculosis remains one of the deadliest infectious diseases in world, and increased number multidrug-resistant extremely drug-resistant strains is a significant reason for concern. This makes discovery novel antitubercular agents cogent priority. We have previously addressed this need by reporting series substituted 2-aminothiazoles capable to inhibit growth actively replicating, nonreplicating persistent, resistant Mycobacterium tuberculosis strains. Clues from structure–activity...
Naja atra subsp. cardiotoxin 1 (CTX-1), produced by Chinese cobra snakes, belonging to Elapidae family, is included in the three-finger toxin family and exerts high cytotoxicity antimicrobial activity too. Using as template mainly tip subsequent β-strand of first "finger" this toxin, different sequences 20 amino acids linear peptides have been designed order avoid toxic effects but maintain or even strengthen partial already seen for complete toxin. As a result, sequence NCP-0 (Naja...
Antibacterial adjuvants are of great significance, since they allow the therapeutic dose conventional antibiotics to be lowered and reduce insurgence antibiotic resistance. Herein, we report that an O-acetylserine sulfhydrylase (OASS) inhibitor can used as a colistin adjuvant treat infections caused by Gram-positive Gram-negative pathogens. A compound binds OASS with nM dissociation constant was tested against six critical pathogens responsible for spreading worldwide, Escherichia coli,...
The bacterium Pseudomonas aeruginosa (PA) and the yeast Candida albicans (CA) are pathogens that cohabit mucosa of respiratory tracts animals humans. Their virulence is largely determined by chemical communication driven quorum sensing systems (QS), cross perception their molecules (QSM) can modulate prevalence one microorganism over other. Aiming to investigate whether some protein components dissolved in mucus layering might interfere with cross-communication these, eventually other...
Snakes are globally considered as pet animals, and millions of ophidians bred in captivity. Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium that can act an opportunistic pathogen man animals frequently present the oral cloacal microbiota healthy ophidians. It cause severe clinical diseases often shows antibiotic resistance. The aim this study was to evaluate prevalence resistance profiles P. isolated from large population sample captive statistical associations with farming...
Grass-seed inhalation is a common problem in canine patients, particular during summer months, migrating upper and lower respiratory tract. Grass awns can harbor bacteria fungi, causing grass seeds foreign body-related disease (GSFBD). Aim of this study was to investigate the aerobic microbial flora isolated from extracted 41 dogs with GSFBD antibiotic susceptibility bacterial strains. Fifty-four were localized diagnostic imaging tests removed by endoscopy The most frequent localizations...
Pseudomonas aeruginosa (PA) may cause suppurative otitis externa with severe inflammation and ulceration in dogs. Multidrug resistance is commonly reported for this organism, creating a difficult therapeutic challenge.The aim of study was to evaluate the vitro antimicrobial activity gel containing 0.5 μg/mL peptide AMP2041, 0.07% chlorhexidine digluconate (CLX), 0.4% Tris 0.1% EDTA on 30 clinical isolates PA from canine externa.Antimicrobial evaluated through minimal bactericidal...
The aim of this trial was to investigate the effects a blend monoglycerides short- and medium-chain fatty acids (SMCFA) on health status growth preweaned male calves from 16 72 days age. in vivo study conducted as complete randomised block design. Twenty Italian Holstein received starter administered ad libitum 6 L milk replacer/day (12% powder concentration) were divided into treated (T) control (C) groups. A preliminary vitro antibiotic activity test SMCFA performed several bacterial...
In recent years, due to the growing phenomenon of antimicrobial resistance, search for alternative strategies antibiotic treatments is increasing and a considerable interest use medical honey in clinical practice has emerged. Honey been used treatment skin lesions, both humans animals. However, knowledge concerning non‑traditional companion animals scarce. The aim this study was assess antibacterial activity standardized (Revamil, BFactory) against bacterial strains isolated from lesions...