Sofia Llahana

ORCID: 0000-0002-3606-5370
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About
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Research Areas
  • Adrenal Hormones and Disorders
  • Pituitary Gland Disorders and Treatments
  • Hormonal Regulation and Hypertension
  • Hormonal and reproductive studies
  • Growth Hormone and Insulin-like Growth Factors
  • Nursing Roles and Practices
  • Diabetes Management and Education
  • Primary Care and Health Outcomes
  • Childhood Cancer Survivors' Quality of Life
  • Interprofessional Education and Collaboration
  • Sexual function and dysfunction studies
  • Sexual Differentiation and Disorders
  • Ovarian function and disorders
  • Chronic Disease Management Strategies
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Diabetes Management and Research
  • Healthcare Systems and Technology
  • Health and Medical Research Impacts
  • Ovarian cancer diagnosis and treatment
  • Stoma care and complications
  • Medication Adherence and Compliance
  • Nursing education and management
  • Pain Management and Placebo Effect
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Obesity and Health Practices

St George's, University of London
2025

City, University of London
2019-2025

City St George's, University of London
2025

University College London
2011-2024

University College Hospital
2011-2024

University College London Hospitals NHS Foundation Trust
2016-2023

National Health Service
2023

University of Ulster
2001

Male hypogonadism (MH) is a common endocrine disorder. However, uncertainties and variations in its diagnosis management exist. There are several current guidelines on testosterone replacement therapy that have been driven predominantly by single disciplines. The Society for Endocrinology commissioned this new guideline to provide all care providers with multidisciplinary approach treating patients MH. This has compiled using expertise from (medical nursing), primary care, clinical...

10.1111/cen.14633 article EN Clinical Endocrinology 2021-11-22

Pregnancies are rare in women with pituitary adenomas, which may relate to hormone excess from secretory subtypes such as prolactinomas or corticotroph adenomas. Decreased fertility also result deficiencies due compression of the gland by large tumours and/or surgical radiation treatment lesion. Counselling premenopausal adenomas about their chance conceiving spontaneously assisted reproductive technology, and optimal pre-conception treatment, should start at time initial diagnosis. The...

10.1530/eje-21-0462 article EN European Journal of Endocrinology 2021-08-23

Individuals with adrenal insufficiency (AI) are at risk of acute crisis and death, particularly during illness or trauma, may require rapid treatment parenteral glucocorticoid such as hydrocortisone (HC) to manage a crisis. Current guidelines recommend timely self-injection in an evolving Little is known about the patient experience emergency injections. We surveyed people regarding success In 2022 survey was conducted through National Adrenal Diseases Foundation website individuals AI their...

10.1016/j.eprac.2025.02.017 article EN cc-by-nc-nd Endocrine Practice 2025-03-01

Appropriate self-management of glucocorticoid therapy (GC) is crucial for patients with adrenal insufficiency (AI). We aimed to describe patients' self-reported nonadherence GC, evaluate perceived doubts about need concerns adverse effects, and dissatisfaction information received GC.Cross-sectional survey.Patients prescribed GC AI (n = 81) from five European countries.Online survey including the Medication Adherence Report Scale (MARS), Beliefs Medicines Questionnaire(©) (BMQ Specific,...

10.1111/cen.12991 article EN cc-by-nc-nd Clinical Endocrinology 2015-12-08

Objective: Adrenal crisis is a life-threatening complication that requires urgent administration of parenteral hydrocortisone. Current patient education interventions remain ineffective, contributing to preventable hospitalisations and deaths. This study explored the lived experiences individuals with adrenal insufficiency, focusing on factors influencing self-management during crises. Methods: qualitative employed online semi-structured interviews adults insufficiency who had experienced at...

10.1530/ec-24-0651 article EN cc-by-nc-nd Endocrine Connections 2025-04-01

Abstract Context Klinefelter syndrome (KS), most commonly arises from a 47, XXY karyotype. While KS affects around 1 in 450-600 male births, an estimated 50-75% of cases go undiagnosed. Individuals with are at increased risk metabolic, cardiovascular and reproductive comorbidities, increasing mortality risk, psychological burden, significantly diminished health-related quality life (HR-QoL) compared to healthy controls. We provide updated review the recent literature on clinical management...

10.1210/clinem/dgaf261 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2025-05-02

Patients report persisting impairment in quality of life (QoL) after treatment for pituitary disease. At present, there is no questionnaire to assess (a) whether patients with disease are bothered by these consequences, and (b) their needs support. To develop validate a disease-specific which incorporates patient perceived bother related the consequences disease, Items Leiden Bother Needs Questionnaire (LBNQ-Pituitary) were formulated based on results recent focus group study (n = 49 items)....

10.1007/s11102-016-0707-4 article EN cc-by Pituitary 2016-01-25

Adrenal crisis is the leading cause of death in patients with adrenal insufficiency, and prevention requires immediate parenteral hydrocortisone administration. However, most do not receive their home emergency injection. Our study aimed to investigate barriers enablers using injections managing crises. This mixed-methods observational utilized an online survey distributed through two U.S.-based patient advocacy groups. A total 688 respondents completed survey, including 485 (70%)...

10.3389/fendo.2025.1544502 article EN cc-by Frontiers in Endocrinology 2025-04-22

Oestrogen antagonizes the action of growth hormone (GH). For women with combined GH and oestrogen deficiency, transdermal oestradiol is more favourable in this regard compared to oral oestradiol. Oral contraceptive pills containing ethinylestradiol (EE) are commonly used young GHD there little information on impact form oestrogen.A case note review deficiency (GHD) attending a tertiary endocrine clinic comparing dose serum insulin-like factor 1 concentrations type exogenous oestrogen.All...

10.1111/j.1365-2265.2011.04277.x article EN Clinical Endocrinology 2011-11-19

Abstract Purpose Successful treatment outcomes of adults with hypothalamic-pituitary disorders necessitate the adoption intricate self-management behaviors, yet current scales for evaluating adherence and satisfaction are inadequate this patient group. This research introduces a novel adherence, knowledge questionnaire (TASK-Q) developed specifically to identify patients’ unmet needs in better assessing managing these disorders. Methods The study was conducted three phases: (1) generating...

10.1007/s11102-024-01425-9 article EN cc-by Pituitary 2024-07-08

The aim of this study was to identify the job title, work setting, qualifications and training paediatric diabetes specialist nurse (PDSN) as well examine composition multidisciplinary team. It also aimed determine who is involved in education explore teaching methods, approaches, tools materials that PDSN uses educational process.A survey design used. Questionnaires, which combined quantitative qualitative were sent 80 participants from eight opportunistically selected regions United...

10.1046/j.1365-2648.2001.01665.x article EN Journal of Advanced Nursing 2001-02-28

This paper is a report of nationwide study diabetes specialist nurses (DSNs) which explored experiences engendered during their role development and factors influencing this process.The the clinical nurse specialists, including that DSN, has been described as advanced, flexible multifaceted. They experience process before being able to function with maximum effectiveness, although limited work exists in literature explores was underpinned by Hamric Taylor's model includes seven phases:...

10.1002/edn.169 article EN cc-by-nc-sa European Diabetes Nursing 2011-04-01

Most patients with Adrenal insufficiency (AI) require lifelong glucocorticoid replacement. They need to increase glucocorticoids during physical illness or major stressful situations and parenteral hydrocortisone in the event of an adrenal crisis. Patients AI have impaired quality life high mortality; approximately 1 6-12 are hospitalised at least once/year from a potentially preventable Adoption self-management behaviours crucial; these include adherence medication, following "sick day...

10.3389/fendo.2023.1207715 article EN cc-by Frontiers in Endocrinology 2023-06-30

Abstract Background Congenital adrenal hyperplasia (CAH) encompasses a rare group of autosomal recessive disorders, characterised by enzymatic defects in steroidogenesis. Heterogeneity management practices has been observed internationally. The International Adrenal Hyperplasia registry (I‐CAH, https://sdmregistries.org/ ) was established to enable insights into CAH and outcomes, yet its global adoption endocrine centres remains unclear. Design We sought (1) assess current amongst clinicians...

10.1111/cen.15043 article EN cc-by Clinical Endocrinology 2024-03-17

A study into the determinants influencing Vitamin D supplementation among women of Bengali descent in UK Background: The prevalence deficiency is widespread, particularly South Asian residing temperate climates such as United Kingdom. Contributory factors encompass dietary habits and conservative dressing practices. Aims: This aims to delineate knowledge, perceptions, UK. Methods: employed semi-structured interviews with origin at a general practice London. deductive thematic analysis was...

10.12968/pnur.2024.35.5.166 article EN Practice Nursing 2024-05-02
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